Azometin içeren yeni polimerik mikrokürelerin sentezi ve antimikrobiyal özellikleri
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Dosyalar
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Düzce Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Tez çalışmasında, polimer bağlı tris(2-aminoetil)amin, o-ftalaldehit ve metal tuzlarının reaksiyonu ile yeni azometin içeren polimerik mikroküreler (AMP-Phatal, AMP-Phatal-Pt, AMP-Phatal-Ni, AMP-Phatal-Mn, AMP-Phatal-Cu ve AMP-Phatal-Co) elde edildi. Polimerlerin yapıları spektroskopik teknikler (element analizi, FT-IR, SEM-EDX, TG-DTA, UV-GB, GPC ve manyetik duyarlılık ölçümü) ile belirlendi. Polimerik mikrokürelerin antimikrobiyal aktiviteleri hastalık etkeni patojenik bakterilere ve mayaya karşı Well-difüzyon yöntemi ile değerlendirildi.
In thesis work, new azomethine containing polymeric microspheres (AMP-Phatal, AMP-Phatal-Pt, AMP-Phatal-Ni, AMP-Phatal-Mn, AMP-Phatal-Cu and AMP-Phatal-Co) were obtained with the reaction of tris(2-aminoethyl)amine polymer-bound, o-phthalaldehyde and metal salts. The structures of the polymers were determined by spectroscopic techniques (elemental analysis, FT-IR, SEM-EDX, TG-DTA, UV-GB, GPC and magnetic sensitivity measurement). The antimicrobial efficacy of the polymers were evaluated using the Well diffusion method against some pathogenic bacteria and yeast.
In thesis work, new azomethine containing polymeric microspheres (AMP-Phatal, AMP-Phatal-Pt, AMP-Phatal-Ni, AMP-Phatal-Mn, AMP-Phatal-Cu and AMP-Phatal-Co) were obtained with the reaction of tris(2-aminoethyl)amine polymer-bound, o-phthalaldehyde and metal salts. The structures of the polymers were determined by spectroscopic techniques (elemental analysis, FT-IR, SEM-EDX, TG-DTA, UV-GB, GPC and magnetic sensitivity measurement). The antimicrobial efficacy of the polymers were evaluated using the Well diffusion method against some pathogenic bacteria and yeast.
Açıklama
Anahtar Kelimeler
Kimya, Chemistry, Antimikrobiyal aktivite, Antimicrobial activity, Polimerik mikroküre, Polymeric microshepere, Schiff bazları, Schiff bases
