Assessment of platelet indices in patients with neurodegenerative diseases: Mean platelet volume was increased in patients with Parkinson's disease

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dc.contributor.authorKoçer, Abdulkadir
dc.contributor.authorYaman, Aslı
dc.contributor.authorNiftaliyev, Elvin
dc.contributor.authorDürüyen, Hümeyra
dc.contributor.authorEryılmaz, Mehmet
dc.contributor.authorKoçer, Emel
dc.date.accessioned2020-04-30T13:32:08Z
dc.date.available2020-04-30T13:32:08Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPlatelets induce chronic inflammation which is a key step in atherosclerosis and may be involved in the progression of neurodegenerative diseases (NDD). We aimed to measure the mean platelet volume (MPV) and platelet count (PLC) in NDD patients. The present study was designed to investigate the platelet function by measuring MPV and PLC in NDD. A total of 182 outpatients with Alzheimer's (AD) or Parkinson's diseases (PD) were included. The control group consisted of 104 healthy subjects. Platelet count was similar between groups. MPV values of PD patients were higher than those of AD patients and controls (P<0.001). MPV correlated negatively with Heohn and Yahr scale (HYS) score (P<0.001). Increased MPV in patients with PD may point to a platelet dysfunction. High-grade inflammation presents with low levels of MPV as seen in PD patients with high HYS scores. © 2013 Abdulkadir Koçer et al.en_US
dc.identifier.doi10.1155/2013/986254en_US
dc.identifier.issn1687-7063
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1155/2013/986254
dc.identifier.urihttps://hdl.handle.net/20.500.12684/105
dc.identifier.volume2013en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofCurrent Gerontology and Geriatrics Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAssessment of platelet indices in patients with neurodegenerative diseases: Mean platelet volume was increased in patients with Parkinson's diseaseen_US
dc.typeArticleen_US

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