Blood cell indices in High-Grade Squamous Intraepithelial Lesions

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dc.contributor.authorGamsızkan, Zerrin
dc.contributor.authorCoşkun, Sinem Kantarcıoğlu
dc.contributor.authorErdemir, Gökhan
dc.contributor.authorYavuzcan, Ali
dc.date.accessioned2023-07-26T11:54:48Z
dc.date.available2023-07-26T11:54:48Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalıen_US
dc.description.abstractLow patient motivation and relatively long procedures can sometimes limit the gains of the PAP test. At this point, the clinician may need additional stimulating tests to persuade patients to perform screening tests. The aim of this study was to determine the predictive value of hematological parameters for the high-grade squamous intraepithelial lesion (HG-SIL). Ninety-one patients possessing HG-SIL with complete blood counts and 111 healthy patients with normal cervical cytology were reviewed retrospectively. The age, WBC, and RBC count were significantly different in patients with HG-SIL than in controls. A cutoff value was found 42.5 for age (42% sensitivity and 58 % specificity, AUC: 0.604), 8.65 for WBC (44% sensitivity and 68% specificity, AUC: 0.570), and 4.47 for RBC (65% sensitivity and 58% specificity, AUC: 0.628) in ROC curve analysis. The results of the study show that the age of the patients, RBC, and WBC counts are important in precancerous intraepithelial lesions. Clinicians should warn female patients in the risk group to have regular gynecological examinations and screenings.en_US
dc.identifier.doi10.5455/medscience.2021.10.355
dc.identifier.endpage824en_US
dc.identifier.issn2147-0634
dc.identifier.issue2en_US
dc.identifier.startpage820en_US
dc.identifier.trdizinid529854en_US
dc.identifier.urihttp://doi.org/10.5455/medscience.2021.10.355
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/529854
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12927
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorGamsızkan, Zerrin
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.titleBlood cell indices in High-Grade Squamous Intraepithelial Lesionsen_US
dc.typeArticleen_US

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