Amanita phalloides ekstraklarının antimikrobiyal etkisinin araştırılması
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Dosyalar
Tarih
2022
Yazarlar
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Dergi ISSN
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Yayıncı
Düzce Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
En zehirli mantar türlerinden olan Amanita phalloides isimli şapkalı mantar türünün kloroform, aseton, metanol ve distile su ile hazırlanan ekstraklarının, Candida parapsilosis, Candida albicans, Metisilin duyarlı Staphylococcus aureus (MSSA), Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa ve Metisilin dirençli Staphylococcus aureus(MRSA) türlerine karşı antimikrobiyal etkisi araştırıldı. Yöntem olarak in vitro disk difüzyon yöntemi kullanıldı. Bulgulara go¨re; en yüksek antibakteriyel aktivitesi MRSA ve MSSA tu¨rlerine kars¸ı bulunmakla birlikte digˆer bakterilere kars¸ı da farklı seviyelerde antibakteriyel aktivite go¨sterdiği saptandı. Sonuç olarak; sadece Amanita phalloides'in distile su ile hazırlanan ekstraktının bakterilere karşı etkisi olduğu fakat antifungal etki göstermediği saptandı.
The antimicrobial effect of Amanita phalloides extracts, one of the most poisonous mushroom species, prepared with chloroform, acetone, methanol and distilled water were investigated against Candida parapsilosis, Candida albicans, Methicillin-susceptible Staphylococcus aureus (MSSA), Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Methicillin-resistant Staphylococcus aureus (MRSA) species. In vitro disc diffusion method was used as a method. According to the findings; While the highest antibacterial activity was against MRSA and MSSA species, it was determined that it showed different levels of antibacterial activity against other bacteria. As a result; It was determined that only the extract of Amanita phalloides prepared with distilled water had an effect against bacteria but did not show an antifungal effect.
The antimicrobial effect of Amanita phalloides extracts, one of the most poisonous mushroom species, prepared with chloroform, acetone, methanol and distilled water were investigated against Candida parapsilosis, Candida albicans, Methicillin-susceptible Staphylococcus aureus (MSSA), Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Methicillin-resistant Staphylococcus aureus (MRSA) species. In vitro disc diffusion method was used as a method. According to the findings; While the highest antibacterial activity was against MRSA and MSSA species, it was determined that it showed different levels of antibacterial activity against other bacteria. As a result; It was determined that only the extract of Amanita phalloides prepared with distilled water had an effect against bacteria but did not show an antifungal effect.
Açıklama
Anahtar Kelimeler
Eczacılık ve Farmakoloji, Pharmacy and Pharmacology
