Effect of isotretinoin use on hematological parameters and biochemical values

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dc.contributor.authorKaragöz, Yalçın
dc.contributor.authorTosun, Mustafa
dc.date.accessioned2023-07-26T11:59:08Z
dc.date.available2023-07-26T11:59:08Z
dc.date.issued2022
dc.departmentDÜ, İşletme Fakültesi, Sağlık Yönetimi Bölümüen_US
dc.description.abstractAim: The aim of this study was to investigate the general effects of oral isotretinoin on hematological parameters and biochemical values, and to identify whether these values vary according to age and gender. Material and Methods: The study included 143 patients diagnosed with moderate or severe acne in the age range of 15-47 years. Patients were monitored retrospectively. Hematological parameters and biochemical values were recorded before treatment, then at the end of the first and third months of the treatment. Results: The serum lipid levels, creatinine, cholesterol, triglyceride and AST values of liver enzymes, and renal function values were found to increase after the onset of treatment. Hematological parameters including LYM, HGB, HCT, RDW, MCV, PLT, MPV and PCT parameters were seen to increase after the onset of treatment, while the NEU parameter decreased. The values of other hematological parameters did not change. Discussion: Although the use of oral isotretinoin has been shown to cause changes in hematological parameters and serum lipid levels, liver and renal function values, these changes usually remain within normal limits and continue with treatment.en_US
dc.identifier.doi10.4328/ACAM.20921
dc.identifier.endpage359en_US
dc.identifier.issn2667-663X
dc.identifier.issue4en_US
dc.identifier.startpage355en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20921
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13642
dc.identifier.volume13en_US
dc.identifier.wosWOS:000729257500001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorKaragöz, Yalçın
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectIsotretinoin; Acne; Hematological Parameters; Biochemical Valuesen_US
dc.subjectTrans-Retinoic Acid; Acne; Apoptosis; Therapyen_US
dc.titleEffect of isotretinoin use on hematological parameters and biochemical valuesen_US
dc.typeArticleen_US

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