Extrahepatic manifestations of chronic viral hepatitis: possible associated complications must not be forgotten in daily clinical practice
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Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş ve Amaç: Hepatit etkeni virüsler kronik karaciğer hastalıklarına yol açmanın yanısıra ekstrahepatik bulgular olarak adlandırılan diğer organ ve dokularda da bozukluklara neden olabilirler. Tedavide ekstrahepatik tutulumları da gözardı etmemek gereklidir. Gereç ve Yöntem: stanbul Tıp Fakültesi Gastroenteroloji Bilim Dalında 1997-2010 yılları arasında takipli toplam 2870 hastada klinik olarak semptomatik ekstrahepatik tutulumu olan 52 hastanın (%2) demografik özellikleri retrospektif olarak değerlendirildi. Bulgular: Elli iki hastadan 27si (%52) hepatit C, 24ü (%46) hepatit B ve 1 (%2) hasta da hem hepatit B hem de hepatit C idi. Bunlardan 25i (%48) erkekti, ortalama yaş 5113 (18-78) yıldı. Otuz iki hasta (%61) sirotik evrede, 20 hasta (%39) ise presirotik evrede idi. Sonuç: Ekstrahepatik tutulumlar genelliklatlanmaktadır. Klinisyenler ekstrahepatik bulguların tanısında daha duyarlı olmalıdırlar.
Background and Aims: Hepatitis viruses induce not only chronic liver diseases but also the impairment of other organs and tissues as extrahepatic manifestations. It is necessary to consider possible complications associated with extrahepatic diseases in the treatment. Materials and Methods: We retrospectively evaluated the demographic features of 52 (2%) patients who had clinically symptomatic extrahepatic manifestations from among 2870 chronic viral hepatitis patients in the Gastroenterology Department of the Istanbul Medical Faculty between 1997 and 2010. Results: Twenty-seven of the 52 patients (52%) had hepatitis C, 24 (46%) hepatitis B, and 1 (2%) both hepatitis B and C. Of these, 25 (48%) were males, and the mean age was 51±13 (range, 18 to 78) years. Thirty-two patients (61%) were cirrhotic, while 20 (39%) were in the precirrhotic stage. Conclusions: Extrahepatic involvement is generally overlooked, and clinicians should be more sensitive to the diagnoses of these manifestations.
Background and Aims: Hepatitis viruses induce not only chronic liver diseases but also the impairment of other organs and tissues as extrahepatic manifestations. It is necessary to consider possible complications associated with extrahepatic diseases in the treatment. Materials and Methods: We retrospectively evaluated the demographic features of 52 (2%) patients who had clinically symptomatic extrahepatic manifestations from among 2870 chronic viral hepatitis patients in the Gastroenterology Department of the Istanbul Medical Faculty between 1997 and 2010. Results: Twenty-seven of the 52 patients (52%) had hepatitis C, 24 (46%) hepatitis B, and 1 (2%) both hepatitis B and C. Of these, 25 (48%) were males, and the mean age was 51±13 (range, 18 to 78) years. Thirty-two patients (61%) were cirrhotic, while 20 (39%) were in the precirrhotic stage. Conclusions: Extrahepatic involvement is generally overlooked, and clinicians should be more sensitive to the diagnoses of these manifestations.
Açıklama
Anahtar Kelimeler
Gastroenteroloji ve Hepatoloji
Kaynak
Akademik Gastroenteroloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
11
Sayı
3
