Seroprevalence of HBsAg and Anti-HCV among HIV Positive Patients

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dc.authoridkumbasar karaosmanoglu, hayat/0000-0002-7716-3006
dc.authoridAltuntas, Ozlem/0000-0002-6508-7368
dc.contributor.authorSahin, Meyha
dc.contributor.authorAydin, Ozlem Altuntas
dc.contributor.authorKaraosmanoglu, Hayat Kumbasar
dc.contributor.authorYildirim, Mustafa
dc.date.accessioned2021-12-01T18:49:32Z
dc.date.available2021-12-01T18:49:32Z
dc.date.issued2021
dc.department[Belirlenecek]en_US
dc.description.abstractObjectives: The study aimed to investigate the seroprevalence of hepatitis B surface antigen (HBsAg) and hepatitis C virus (anti-HCV) in human immunodeficiency virus (HIV) infected patients and to evaluate the results according to risk factors in our hospital in Istanbul, which was one of the centers where HIV-infected patients were followed up the most in our country. Materials and Methods: The medical files of 611 HIV-infected patients who were followed up in our infectious diseases and clinical microbiology outpatient clinic between 1999 and 2016, were analyzed to determine the seroprevalence of HBsAg and anti-HCV retrospectively. HIV-monoinfected patients, HIV+HBV-coinfected patients, and HIV+HCV-coinfected patients were examined separately in terms of demographic characteristics and risk factors, and compared with each other. Results: Of the patients 86.6% were male. The mean age of the patients was 37.0 +/- 11.2 (16-83). More than one-third of patients were 30-39 years old. Of the patients 43.7% were men who had sex with men (MSM). Of the patients, 5.8% were HBsAg-positive and 14.7% (236) of patients were positive for isolated anti-HBc IgG. The HBV-DNA positivity ratio was determined as 8.7% in the isolated anti-HBc IgG positive group. Of the patients 2% were anti-HCV positive, and 0.9% were HCV-RNA positive. The prevalence of HIV/HCV coinfection was statistically significantly higher in intravenous (IV) drug users than HIV-monoinfected patients (p<0.001). Conclusion: It is not sufficient to evaluate HBsAg alone in HIV-infected individuals. Anti-HBc IgG and HBV-DNA should also be evaluated. Anti-HCV antibody must be tested especially in patients with IV drug addiction.en_US
dc.identifier.doi10.4274/vhd.galenos.2020.2019.0043
dc.identifier.endpage30en_US
dc.identifier.issn1307-9441
dc.identifier.issn2147-2939
dc.identifier.issue1en_US
dc.identifier.startpage24en_US
dc.identifier.urihttps://doi.org/10.4274/vhd.galenos.2020.2019.0043
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10738
dc.identifier.volume27en_US
dc.identifier.wosWOS:000647688100005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofViral Hepatit Dergisi-Viral Hepatitis Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatitis B virusen_US
dc.subjecthepatitis C virusen_US
dc.subjecthuman immunodeficiency virusen_US
dc.subjectHuman-Immunodeficiency-Virusen_US
dc.subjectHepatitis-B-Virusen_US
dc.subjectInfected Patientsen_US
dc.subjectRisk-Factorsen_US
dc.subjectC Virusen_US
dc.subjectPrevalenceen_US
dc.subjectCoinfectionen_US
dc.titleSeroprevalence of HBsAg and Anti-HCV among HIV Positive Patientsen_US
dc.typeArticleen_US

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