Synthesis of novel polymers containing Schiff base as potential antimutagenic and antimicrobial agents

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dc.authorscopusid25230320600
dc.authorscopusid57223896901
dc.authorscopusid56417386800
dc.authorscopusid55771966200
dc.authorscopusid9839684700
dc.authorscopusid7003921401
dc.contributor.authorNartop, D.
dc.contributor.authorTokmak, E.
dc.contributor.authorÖzkan, E. H.
dc.contributor.authorKızıl, H. E.
dc.contributor.authorÖğütcü, H.
dc.contributor.authorAğar, G.
dc.contributor.authorAllı, S.
dc.date.accessioned2021-12-01T18:39:00Z
dc.date.available2021-12-01T18:39:00Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractIn this research study, two novel polymers including Schiff base were prepared by condensation reaction of polystyrene-A-NH2 with 5-nitro-2-thiophenecarboxaldehyde/or 5-(2-nitrophenyl)-2-furancarboxaldehyde. The synthesized polymers were evaluated using the elemental analysis, infrared spectroscopy (IR), gel permeation chromatography (GPC), thermal gravimetric analysis (TG/DTA). In addition, the antimicrobial and antimutagenic study of the polymers were reported. The antibacterial and antifungal activity were investigated using the diffusion method against pathogenic bacterial strains. PA-TC and PA-FC polymers exhibited the highest antimicrobial activity against the S. typhi H. and P. vulgaris, respectively. PA-FC polymer revealed the highest antifungal activity against C. albicans. The antimutagenic effects were evaluated using the sister chromatid exchange (SCE) and micronucleus (MN) methods against the sodium azide (NaN3) in human lymphocyte cells. The results demonstrated that the PA-FC polymer have strong antimutagenic properties, especially in the concentration of 20 µg/mL. © 2020 by SPC (Sami Publishing Company)en_US
dc.identifier.doi10.26655/jmchemsci.2020.4.6
dc.identifier.endpage372en_US
dc.identifier.issn26514702
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85106368600en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage363en_US
dc.identifier.urihttps://doi.org/10.26655/jmchemsci.2020.4.6
dc.identifier.urihttps://hdl.handle.net/20.500.12684/9955
dc.identifier.volume3en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSami Publishing Companyen_US
dc.relation.ispartofJournal of Medicinal and Chemical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAntimutagenic effecten_US
dc.subjectPolymers containingen_US
dc.subjectPolystyrene-A-NH2en_US
dc.subjectSchiff baseen_US
dc.subjectSodium azideen_US
dc.titleSynthesis of novel polymers containing Schiff base as potential antimutagenic and antimicrobial agentsen_US
dc.typeArticleen_US

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