A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis

dc.contributor.authorCoşkun, Gökhan
dc.contributor.authorTorun, Serkan
dc.contributor.authorAkbaş, Türkay
dc.contributor.authorAkin, Gul
dc.contributor.authorÖnbaş, Ömer
dc.date.accessioned2024-08-23T16:08:20Z
dc.date.available2024-08-23T16:08:20Z
dc.date.issued2022en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors. Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi- ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed. Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con- ditions that disrupt phagocytic activity of macrophages and predispose to IA.en_US
dc.identifier.doi10.14744/etd.2021.58812
dc.identifier.endpage620en_US
dc.identifier.issn2149-2247
dc.identifier.issue6en_US
dc.identifier.startpage618en_US
dc.identifier.trdizinid1173257en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1173257
dc.identifier.urihttps://hdl.handle.net/20.500.12684/15257
dc.identifier.volume44en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleA Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitisen_US
dc.typeArticleen_US

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