Prevalence of High-Risk Human Papillomavirus Types and Their Association with Cervical Squamous Cell Carcinoma, and High-and Low-Grade Squamous Intraepithelial Lesions in Turkish Women

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dc.authorscopusid55955431000
dc.authorscopusid57218497894
dc.authorscopusid15766595100
dc.authorscopusid55871120703
dc.authorscopusid56495523600
dc.authorscopusid7003794103
dc.contributor.authorErkinüresin, Taşkın
dc.contributor.authorKartal, Esra
dc.contributor.authorÜstünyurt, Emin
dc.contributor.authorDemirci, Hakan
dc.contributor.authorKilitçi, Asuman
dc.contributor.authorÖnal, Binnur
dc.date.accessioned2023-07-26T11:51:23Z
dc.date.available2023-07-26T11:51:23Z
dc.date.issued2023
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.description.abstractBackground: This study aimed to investigate human papillomavirus (HPV) type prevalence in our region and the relationship between uterine cervical HPV types and squamous cell carcinoma (SCC)/intraepithelial lesions. Methods: HPV test results were obtained from patient file archives of the Gynecology and Obstetrics Clinic. Pathology report results were obtained from the digital records of the Pathology Laboratory and the patient file archives of the Gynecology and Obstetrics Clinic in 2018. Results: The most frequently detected was HPV16 (29.2%), followed by HPV51 (13.1%), HPV56 (11%), HPV31 (9.2%), HPV52 (8.4%), and HPV68 (8.2%). HPV16 was positive in 50% of patients diagnosed with SCC, 54.9% of patients with HSIL, 27% of patients with LSIL, and 25% of cases diagnosed as benign (P<0.001). HPV18 was positive in 25% of patients diagnosed with SCC, 11% of patients with HSIL, 4.7% of patients with LSIL, and 5.2% of cases diagnosed as benign (P=0.019). Conclusion: The most frequent hrHPV genotype was HPV16, followed by HPV51, HPV 56, and HPV 31. There is an increase in the frequency of HPV51 and HPV56. HPV51, not included in HPV vaccines and is the second most frequent, should be included in these vaccines. In addition, although the frequency of HPV18 has decreased, HSIL and SCC generation is still high together with HPV16. © 2023 Erkinüresin et al.en_US
dc.identifier.endpage621en_US
dc.identifier.issn2251-6085
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85149111902en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage612en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12552
dc.identifier.volume52en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÖnal, Binnur
dc.language.isoenen_US
dc.publisherTehran University of Medical Sciencesen_US
dc.relation.ispartofIranian Journal of Public Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCervical carcinomaen_US
dc.subjectCytologyen_US
dc.subjectEpithelial abnormalityen_US
dc.subjectHigh-risk human papillomavirusen_US
dc.subjectType prevalenceen_US
dc.titlePrevalence of High-Risk Human Papillomavirus Types and Their Association with Cervical Squamous Cell Carcinoma, and High-and Low-Grade Squamous Intraepithelial Lesions in Turkish Womenen_US
dc.typeArticleen_US

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