TÜRKİYE’DE EN ÇOK REÇETELENEN ?-LAKTAM (SEFALEKSİN, SEFAZOLİN, SEFOPERAZON, SEFAKLOR, SEFUROKSİM, AMPİSİLİN) GRUBU ANTİBİYOTİKLERİ İÇEREN ATIKSULARIN FENTON PROSESİ İLE ARITILABİLİRLİĞİNİN ARAŞTIRILMASI
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Dosyalar
Tarih
2019
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Sulara karışan kirleticiler, gelişen sanayileşme ve teknoloji ile birlikte her gün çeşitlilik gösterdiğinden bu kirleticilerin kontrol edilmesinde kullanılan analiz teknolojileri sınırlı ve bazı alanlarda etkisiz kalmaktadır. Ülkemiz ve dünya genelinde yaygın kullanımları nedeniyle ve çevrede oluşturduğu mikroorganizma rezistansı için en tehlikeli kirletici türü olarak antibiyotik bileşikleri kabul edilmiştir. Gelişen dünyada geniş kullanıma sahip antibiyotikler, hastahanelerde ve veterinerlikte çok sık kullanılmaktadırlar. Klasik arıtma yöntemleri (fiziksel, kimyasal, biyolojik) ile giderilemeyen antibiyotikler alıcı ortamlarda çevresel sorunlara neden olmaktadır. Antibiyotiklerin çevreye girişi; vücuttan atılma sıklığına, kullanılan doz ve miktarına, atık su arıtma tesisindeki mikroorganizmaların metabolik dönüştürme yeteneğine ve katılara tutunma eğilimine bağlıdır. Yüksek antibiyotik konsantrasyonları yüzeysel sularda suda yaşayan organizmalara toksik etki yapmakta, düşük antibiyotik konsantrasyonları ise antibiyotik direnci oluşturmaktadır. Bu nedenle antibiyotiklerin çevreye kontrolsüz girişleri engellenmelidir. Bu çalışmada, Kuzey Avrupa’da ve ülkemiz genelinde geniş kullanım alanına sahip endokrin bozucu özellikteki antibiyotik bileşiklerinden ?-laktam grubu (sefazolin, sefaleksin, sefoperazon, sefuroksim, sefaklor ve ampisilin) antibiyotikleri içeren atıksuların, fenton prosesi kullanılarak arıtımı incelenmiştir. Seçilen antibiyotikler ultra saf suda çözünerek, sentetik atıksu örnekleri 300 mg/L konsantrasyonunda (her antibiyotik bileşiği konsantrasyonu: 50 mg/L) hazırlanmıştır. Yapılan deneysel çalışmalar sonucunda, pH:4, [Fe/H2O2]:1/10 olarak belirlenen optimum koşullar sağlandığında, >%80 KOİ, >%60 TOK giderim verimleri elde edilmiştir. Bu sonuçlar doğrultusunda ileri arıtma proseslerinden fentonun, seçilen antibiyotiklerin gideriminde etkili bir yöntem olduğu anlaşılmıştır.
The pollutants involved in the waters vary with each passing day with the industrialization and technology, so analysis technologies used to control these pollutants are limited and in some areas ineffective. Antimicrobial compounds have been accepted as the most dangerous pollutant species for the microorganism resistance caused by their widespread use in our country and around the world. Antibiotics that are widely used in the developing world are frequently used in hospitals and veterinary medicine. Antibiotics that cannot be removed by classical treatment methods (physical, chemical, biological) cause environmental problems in receiving environments. Introduction of antibiotics to the environment; It depends on the frequency of excretion, the dosage and amount used, the ability of the microorganisms in the wastewater treatment plant to metabolically transform and the tendency to hold on to the solids. High antibiotic concentrations have a toxic effect on aquatic organisms in superficial waters and low antibiotic concentrations constitute antibiotic resistance. For this reason, uncontrolled access of antibiotics to the environment should be prevented. In this study, the treatment of wastewater containing ?-lactam group (cefazolin, cephalexin, cefoperazone, cefuroxime, cefaclor and ampicillin) antibiotics with endocrine disrupting antibiotic compounds in Northern Europe and throughout the country was investigated by using the fenton process. The selected antibiotics were dissolved in ultra-pure water and the synthetic wastewater samples were prepared at a concentration of 300 mg/L (each antibiotic compound concentration: 50 mg/L). As a result of the experimental studies, the optimum conditions of pH: 4, [Fe/H2O2]: 1/10 were obtained, and >80% COD, >60% TOC removal efficiencies were obtained. According to these results, it is understood that fenton is one of the advanced treatment processes and it is an effective method for removing selected antibiotics.
The pollutants involved in the waters vary with each passing day with the industrialization and technology, so analysis technologies used to control these pollutants are limited and in some areas ineffective. Antimicrobial compounds have been accepted as the most dangerous pollutant species for the microorganism resistance caused by their widespread use in our country and around the world. Antibiotics that are widely used in the developing world are frequently used in hospitals and veterinary medicine. Antibiotics that cannot be removed by classical treatment methods (physical, chemical, biological) cause environmental problems in receiving environments. Introduction of antibiotics to the environment; It depends on the frequency of excretion, the dosage and amount used, the ability of the microorganisms in the wastewater treatment plant to metabolically transform and the tendency to hold on to the solids. High antibiotic concentrations have a toxic effect on aquatic organisms in superficial waters and low antibiotic concentrations constitute antibiotic resistance. For this reason, uncontrolled access of antibiotics to the environment should be prevented. In this study, the treatment of wastewater containing ?-lactam group (cefazolin, cephalexin, cefoperazone, cefuroxime, cefaclor and ampicillin) antibiotics with endocrine disrupting antibiotic compounds in Northern Europe and throughout the country was investigated by using the fenton process. The selected antibiotics were dissolved in ultra-pure water and the synthetic wastewater samples were prepared at a concentration of 300 mg/L (each antibiotic compound concentration: 50 mg/L). As a result of the experimental studies, the optimum conditions of pH: 4, [Fe/H2O2]: 1/10 were obtained, and >80% COD, >60% TOC removal efficiencies were obtained. According to these results, it is understood that fenton is one of the advanced treatment processes and it is an effective method for removing selected antibiotics.
Açıklama
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Kaynak
Uludağ Üniversitesi Mühendislik Fakültesi Dergisi
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Scopus Q Değeri
Cilt
24
Sayı
1
