Yazar "Teberik, Kuddusi" seçeneğine göre listele
Listeleniyor 1 - 20 / 33
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Assessment of Central Corneal Thickness, Intraocular Pressure and Retinal Nerve Fiber Layer Thickness at Women with Polycystic Ovary Syndrome(Duzce Univ, 2017) Teberik, Kuddusi; Sağlam, Hakan; Başbuğ, Alper; Karaaslan, Musa; Kaya, Murat; Sungur, Mehmet AliObjective: To compare intraocular pressure, central cornea thickness, anterior chamber depth, axial length and thickness of retina nerve fiber layer between women with polycystic ovary syndrome and healthy at the same age segment. Methods: Between August 2015-January 2016, 46 women who have polycystic ovary syndrome and 53 healthy women have been included to the study. After a complete ophthalmologic examination, intraocular pressure, central cornea thickness, anterior chamber depth, axial length and retinal nerve fiber layer thickness were investigated. In the statistical analysis of the data, Independent Samples t test was utilized to compare the groups. Results: While mean age was 23.4 +/- 4.5 (16-35) in the group with polycystic ovary syndrome, average age level was found as 24.0 +/- 6.1 (18-54) among the controls (P=0.549). Intraocular pressure values were measured and determined as 17.7 +/- 2.6 mmHg in the group with polycystic ovary syndrome, while the values were 15.2 +/- 2.4 mmHg in the controls (P <0,001). Although it was 79.4 +/- 10.2 mu m in the group with polycystic ovary syndrome, retinal nerve fiber layer thickness in the nasal quadrant was found to be 73.8 +/- 10.9 mu m among the controls (P <0.001). Conclusion: We found that the increased levels seen in intraocular pressure and retinal nerve fiber layer thickness in the nasal quadrants of the patients with polycystic ovary syndrome were statistically significance. Hence, we recommend that the patients with polycystic ovary syndrome should be specially analyzed as to eye assessment.Öğe Association of ABO blood groups and Rh factor with retinal and choroidal thickness(Sage Publications Ltd, 2019) Teberik, Kuddusi; Eski, Mehmet TahirPurpose: To evaluate if ABO blood group and Rh factor have an effect on retinal and choroidal thickness. Methods: This study was designed prospectively. Retinal nerve fiber layer, retinal, and choroidal thicknesses were measured with spectral-domain optical coherence tomography. Retinal and choroidal thickness measurements (one subfoveal, three temporal, and three nasal) were obtained at 500-mu m intervals up to 1500 mu m with the caliper system. Results: In this study, 109 male and 151 female, 260 individuals in total were included. There were 125 subjects in group A, 29 in group B, 34 in group AB, and 72 in group O. Rh factor was positive in 194 subjects and negative in 66. There was no significant difference between the groups regarding age (p = 0.667). The groups did not show any statistical difference in retinal nerve fiber layer thickness. There was significant difference found for mean retinal thickness at temporal 1000 mu m when four groups were compared (p = 0.037). No statistically significant difference was detected for the remaining retinal and choroidal sectoral regions. The groups did not statistically significantly differ concerning Rh factor (p > 0.05). Conclusion: Although we found a significant difference in retinal thickness in the temporal retina between group B with group A and group O, we suggest that both blood group and Rh factor have no effect on retinal and choroidal thickness.Öğe Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema(2018) Teberik, Kuddusi; Eski, Mehmet Tahir; Kaya, MuratObjectives: To determine the correlation between central corneal thickness (CCT) and central macularthickness (CMT), and fasting plasma glucose levels and HbA1c levels before diabetic macular edema (DME)in type 2 diabetes mellitus (DM) patients without diabetic retinopathy.Methods: Forty-four eyes of subjects diagnosed with type 2 DM, and 45 healthy control subjects participatedin this study. Detailed ophthalmologic examination was performed with all participants. CMT was measuredin both groups by Spectral-domain optical coherence tomography. CCT measurements were made with anEchoscan US-500 ultrasonic pachymeter. Blood biochemical tests for glycated hemoglobin (HbA1c) and fastingplasma glucose levels were run on all patients.Results: The results of the study showed that the mean CCT was significantly thicker in type 2 DM patients563.84 33.25 ?m than in the controls 550.13 28.41 ?m (p 0.039). The mean of CMT was 231.27 37.74?m in the study group and 225.38 38.33 ?m in the control group (p 0.05). No relationship was foundbetween CCT and CMT and HbA1c level in the study and control groups.Conclusions: The mean CCT was significantly thicker in type 2 DM patients without diabetic retinopathy thanin the controls. The mean CMT is thicker in type 2 DM patients without diabetic retinopathy patients than inthe controls, but this difference was not statistically significant. Optical coherence tomography can be a perfectdetector for early detection of DME.Öğe Compare of optic coherence tomography parameters in recreational synthetic tetrahydrocannabinol use and healthy control(Taylor & Francis Ltd, 2023) Eski, Mehmet Tahir; Teberik, Kuddusi; Taha, Sezer; Buken, Bora; Sonmez, Feruza TuranPurposeTo evaluate retinal thickness (RT), retinal nerve fiber layer thickness (RNFLT), and choroidal thickness (CT) changes in synthetic cannabinoid (SC) users.MethodsThis prospective study evaluated the RT, RNFLT, and CT values of 56 SC users and 58 healthy controls. The individuals using SCs were referred to us by our hospital's forensic medicine department. Retinal and choroidal images were obtained using spectral-domain optical coherence tomography (OCT). Measurements (one subfoveal, three temporals, three nasal) were taken at 500 & mu;m intervals up to 1500 & mu;m using the caliper system. Only the right eye was used for subsequent analysis.ResultsMean ages were 27.7 & PLUSMN; 5.7 years in the SC-user group and 25.4 & PLUSMN; 6.7 in the control group. Subfoveal Global RNFLT was in the SCs group 102.3 & PLUSMN; 10.5 & mu;m and 105.6 & PLUSMN; 20.2 & mu;m in the control group (p = 0.271). Subfoveal CT was in the SC group mean of 316.1 & PLUSMN; 100.2 & mu;m and in the control group mean 346.4 & PLUSMN; 81.8 & mu;m (p = 0.065). RT, T500 (283.3 & PLUSMN; 36.7 & mu;m, 296.6 & PLUSMN; 20.5 & mu;m, p = 0.011) and N1500 (355.1 & PLUSMN; 14.3 & mu;m, 349.3 & PLUSMN; 18.1 & mu;m, p = 0.049) were significantly higher in the SC group than in the control group, respectively.ConclusionAnalysis of OCT findings of individuals who had been using SC for more than one year revealed no statistically significant difference between RNFLT and CT, although N1500 was significantly higher in RT. Further studies in the field of OCT are important to explore the pathology of SCÖğe Comparison of Anterior Segment Measurements in Obese Children and Healthy Control Group(Duzce Univ, Fac Medicine, 2023) Eski, Mehmet Tahir; Teberik, Kuddusi; Sezer, Taha; Arslanoglu, IlknurOphthalmology, Objective: To evaluate anterior segment parameters in obese children. Methods: Fifty-five obese and 30 control group children subjects participated. All participants and the control group were examined and anthropometric measurements were made. The measurements of fasting blood glucose (FBG), systolic blood pressure (SBP) triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), and insulin values were performed. The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Each participant underwent a detailed ophthalmic examination and intraocular pressure (IOP), central corneal thickness (CCT), anterior chamber depth (ACD) and lens thickness (LT) were measured. Results: The gender distribution of the groups was similar (p=0.893). The mean of CCT and LT were significantly higher in the obese group (572.9 & PLUSMN; 14.5 vs. 559.5 & PLUSMN; 10.1 & mu;m, p=0.001; 3.6 & PLUSMN; 0.14 vs. 3.48 & PLUSMN; 0.25 mm, p=0.007). No significant difference was found between the obese and control groups in terms of other parameters. Body mass index (BMI) and waist circumference (WC) had a significant negative correlation with LT control groups. The obese group showed a significant positive correlation between IOP and TG (r=0.276, p=0.042), and a significant negative correlation with HDL-C (r=-0.273, p=0.043). In the control group, there was a significant positive correlation between IOP and BMI (r=0.389, p=0.034), WC (r=0.497, p=0.005), HOMA-IR (r=0.384, p=0.036), Insulin (r=0.407, p=0.026), and a significant negative correlation with TC (r=-0.511, p=0.004). A significantly positive correlation between ACD and LDL-C (r=0.371, p=0.043) and a significantly negative correlation between HOMA-IR in the control group were detected (r=-0.682, p=0.000). Conclusions: The obese group had higher CCT and LT than the control groups.Öğe Comparison of central corneal thickness and intraocular pressure measured with two different tono/pachymeter devices in non-glaucomatouse children(Sage Publications Ltd, 2021) Teberik, Kuddusi; Eski, Mehmet Tahir; Ankarali, HandanPurpose: The goal of this research is to compare the intraocular pressure (IOP) and the mean central corneal thickness (CCT) values obtained from the measurements with Nidek NT-530P and Canon TX-20P devices with the values obtained by ultrasound pachymetry (UP) and Goldmann applanation tonometry (GAT) in children. Methods: This prospective study was conducted with 119 healthy children. The measurements were repeated three times for each eye. The intraclass correlation coefficient (ICC) was used to assess the correlation between the measurements obtained from different devices. The Bland-Altman plot was used to analyze the agreement between two different devices graphically. The measurements were taken in the same order in all subjects: TX-20P, NT-530P, UP, and GAT. Results: The mean age of the children was 10.1 +/- 3.2 (6-17) years. The mean CCT values for the eyes were 568.90 and 569.68 (TX-20P), 571.44 and 566.37 (NT-530P), 564.77 and 564.67 mu m UP, (right and left, respectively). The highest correspondence observed for CCT was between UP and NT-530P devices (ICC, 0.982, the left eye). The mean IOP measurements for Canon TX-20P, NT-530P, and GAT were 16.5 +/- 3.2, 16.3 +/- 3.2, and 16.8 +/- 3.6 mmHg for the right eyes, respectively, while those for the left eyes were 16.6 +/- 3.1, 16.2 +/- 3.3, and 16.8 +/- 3.7 mmHg. The highest correspondence was noted between measurements obtained using GAT and Nidek NT-530P devices (ICC, 0.945, in the left eye). Conclusion: Tono/pachymetry devices in the healthy children are provides significant agreements with the gold standard methods for IOP and CCT measurements. Clinical Trial Registration number: 2016-94Öğe Comparison of central corneal thickness with four different optical devices(Springer, 2018) Teberik, Kuddusi; Eski, Mehmet Tahir; Kaya, Murat; Ankaralı, HandanBackgroundTo compare the consistency between the average scores of the contact central corneal thickness measurements from ultrasound pachymetry devices still gold standard, such as iPac((R)) and Echoscan US-500, and noncontact measurements via Pentacam HR and Sirius topography.MethodsThis prospective study, subsequently admitted to the ophthalmology department, 76 healthy individuals were performed. The measurements were repeated three times for each eye, and average scores were statistically analyzed on the same day and almost at the same time. While measuring the eyes, Pentacam HR, Sirius topography, iPac((R)), and Echoscan US-500 were used, respectively. The inter-rater agreement of measurements from the devices was assessed with intraclass correlation coefficient, and 95% Confidence Interval and p values demonstrating statistically significance were also presented. In the graphical assessment of the agreement, the Bland-Altman graph was used.ResultsAmong 76 study participants, 43 (56.6%) were composed of women, and age level was 38.612.5years, ranging between 18 and 69. It was observed that the highest agreement was between the measurements obtained from Echoscan US-500 and iPac((R)) devices, but the agreement between the measurements of different devices was higher than 0.90. Bland-Altman graphics were also investigated; the results of four different devices were seen to be consistent with one another.ConclusionsTherefore, the devices we compared in the study can be used as alternatives to one another due to the higher consistency between CCT measurements provided with through UP devices of Echoscan US-500 and iPac((R)), and Pentacam HR and Sirius topography devices. p id= Par5 Clinical Trial Registration number: 2016/112Öğe Comparison of the effects of 3 different anti-VEGF drugs on cornea thickness, lens thickness and anterior chamber depth: Case-Control Study(2023) Eski, Mehmet Tahir; Teberik, Kuddusi; Sezer, TahaTo compare the long-term effects of 3 different anti-VEGF molecules on the lens, cornea and anterior chamber in phakic patients who have received consecutive intravitreal injections. 157 patients who did not have corneal pathology but were treated with 1.25mg/0.05ml intravitreal bevacizumab, 0.5mg/0.5ml ranibizumab or 2mg/0.05ml aflibercept injections due to diabetic macular edema were retrospectively analyzed in our clinic. Patients who received three consecutive monthly injections were included to the study. Corneal thickness, lens thickness and anterior chamber depth measurements which were taken before the injections, 1 month after the first injection, 1 month after the second injection, and 1 month after the third injection were used in the study. There was no statistical difference between the bevacizumab, ranibizumab, aflibercept and control group in terms of preoperative specifications such as number of patients, gender and age average. A statistically significant difference was found between the 4 anterior chamber depth measurements in the control group, Ranibizumab drug group, and Bevacizumab and Aflibercept drug groups (p<0.001, p=0.026; p=0.07, p<0.001, respectively). Anterior chamber depth of the Ranibizumab and Bevacizumab patients decreased in the first month and increased in the second and third months. However, anterior chamber depth of the Aflibercept patients increased over time. As a result of our study; we concluded that three different anti- VEGF drug molecules have an effect on the anterior camera.Öğe A Comparison of Three Different Photoscreeners in Children(Slack Inc, 2018) Teberik, Kuddusi; Eski, Mehmet Tahir; Kaya, Murat; Ankaralı, HandanPurpose: To compare the results obtained from three non-cycloplegic handheld photorefractometers with cycloplegic autorefractometry (Topcon KR-8100; Topcon Corporation, Tokyo, Japan) measurement in children. Methods: The refractive status of 238 eyes in 119 healthy children was assessed. The values acquired using photorefraction with the non-cycloplegic PlusoptiX A12 (Plusoptix GmbH, Nuremberg, Germany), Retinomax K-plus 3 (Righton, Tokyo, Japan), and Spot Vision Screener (Welch Allyn, Skaneateles Falls, NY) devices were compared with those obtained from the cycloplegic Topcon KR-8100. The agreement between the measurements was assessed using the intraclass correlation coefficient. Results: The mean age was 10.1 +/- 3.2 years (range: 6 to 17 years). The mean spherical value for the right eyes was 0.38 diopters (D) (range: -4.50 to 6.25 D) for the Plusoptix A12; 0.45 D (range: -4.50 to 6.25 D) for the Spot Vision Screener; -1.15 D (range: -8.75 to 6.50 D) for the Retinomax K-plus 3; and 0.62 (range: -4.50 to 6.00) for the Topcon KR-8100. The mean spherical equivalent value for the right eyes was 0.41 D (range: -4.50 to 7.90 D) for the Plusoptix A12; 0.18 D (range: -4.75 to 6.13 D) for the Spot Vision Screener; -1.30 D (range: -10.50 to 6.38 D) for the Retinomax K-plus 3; and 0.67 D (range: -4.00 to 6.00 D) for the Topcon KR-8100 (for the right eyes). Conclusions: The photorefractometer method was beneficial in the measurement of refractive errors of school-aged children. The PlusoptiX A12 photorefractometer method may eliminate the need for cycloplegia in the detection of refractive errors in children.Öğe The Effects of Long-term Growth Hormone Treatment on Ocular Findings(Georg Thieme Verlag Kg, 2023) Eski, Mehmet Tahir; Teberik, Kuddusi; Bolu, Semih; Ankarali, Handan; Kaya, Murat; Arslanoglu, IlknurPurpose This study aimed to examine the long-term changes in anterior chamber depth (ACD), central corneal thickness (CCT), axial length (AxL), peripapillary retinal nerve fibre layer thickness (RNFLT), peripapillary ganglion cell layer - inner plexiform layer (GCL-IPL) thickness, and peripapillary choroidal thickness (ChT) after rhGH replacement treatment in paediatric patients with IGHD, compared to healthy controls.Methods Twenty-two children with IGHD including 12 girls and 10 boys were enrolled in the study group, and 30 (16 girls, 14 boys) healthy children composed the control group. A detailed ophthalmological examination was performed for each participant. ACD, CCT, AxL, peripapillary RNFLT, GCL-IPL thickness and ChT measurements were performed before the rhGH replacement treatment and in the 12th month of the post-treatment period, as well as the corresponding visits in the control group. AxL ultrasound pachymetry (CCT), peripapillary RNFL thickness, peripapillary RNFLT, GCL-IPL thickness, and peripapillary ChT parameters were measured by spectral-domain optical coherence tomography.Results The mean age of the groups were similar (p = 0.143). 12-month CCT, ACD, and AxL measurements of the study group showed significantly higher results than the pre-treatment measurements (p = 0.005, p = 0.024, and p = 0.002, respectively). Similarly, the mean RNFLT and ChT measurements of the study group obtained from all sectors were significantly higher in the 12th-month visit (p < 0.001 for both) other than the RNFLT, and GCL-IPL thickness measurements (p > 0.05 for all). However, all these parameters were similar at pre- and post-treatment visits in the control group (p > 0.05 for all). The mean pre-treatment values of all these parameters were significantly lower in the study group compared to the control group (p < 0.05 for all), other than the RNFLT, GCL-IPL thickness measurements (p > 0.05 for all), while the mean post-treatment values of all these parameters in both groups were similar at month 12 (p > 0.05 for all).Conclusion GH replacement treatment in childhood may play an important role in the development of the neural retina and can be effective on the anterior segment, RNFLT and ChT measurements.Öğe The Effects of Nasal Septum Deviation on Ocular Examination Findings: Does Deviated Nasal Septum Cause Impaired Vision?(Duzce University Medical School, 2022) Akcan, Fatih Alper; Teberik, Kuddusi; Belada, Abdullah; Ünlü, İ.; Dündar, Y.Aim: Nasal obstruction due to nasal septum deviation is associated with systemic diseases such as cardiopulmonary disease, neurological and vascular problems. But the effect of pure nasal deviation on the ocular system has not been precisely investigated. The aim of this study was to analyze the association of nasal septal deviation with ocular examination findings. Material and Methods: Twenty-seven adult patients underwent septoplasty and 31 controls were included in the study. The study group was conducted on patients with pure nasal septum deviation which is significantly obstructing the nasal airway (>50%). In ophthalmological examination; peripapillary retinal nerve fiber layer, macular and choroidal thickness measurements were obtained. The examination findings were compared between the study and control groups. Results: The mean macular thicknesses at nasal-500?m were 305.89±32.79 and 287.87±25.00 in the study and control groups, respectively (p=0.021). The mean macular thicknesses at nasal-1000?m were 353.04±21.28 and 341.16±17.97 in the study and control groups, respectively (p=0.025). The mean thickness of choroid was statistically significantly different at central (p=0.036) and peripheral measurements; nasal-500?m (p=0.020); nasal-1000?m (p=0.001); nasal-1500?m (p<0.001); temporal-500?m (p=0.023) and temporal-1000?m (p=0.045). No statistically significant difference was found between the two groups according to ocular tension, thickness of cornea, keratometry, anterior chamber depth, axial length of cornea, and retinal nerve fiber layer thickness. Conclusion: This is one of the pioneer studies evaluating the ocular examination findings in patients with nasal septum deviation. Our results indicate the increased thickness of both macula and choroid in patients with nasal septum deviation. © 2022, Duzce University Medical School. All rights reserved.Öğe The effects of non-invasive mechanic ventilator modes on intraocular pressure in COPD patients with hypercapnic respiratory failure(Wiley, 2020) Aytekin, Fuat; Gulhan, Pinar Yildiz; Teberik, Kuddusi; Balbay, Ege Gulec; Iritas, Ilter; Ercelik, Merve; Balbay, Oner AbidinBackground Chronic obstructive pulmonary disease (COPD) is not fully reversible disease that is characterized by progressive restricting airflow. Non-invasive mechanical ventilation (NIMV) treatment can be used in COPD patients who had type 2 respiratory failure. This study aimed to determine the effect of BPAP S/T and AVAPS modes on intraocular pressure (IOP), central corneal thickness (CCT) in 40 type 2 respiratory failure patients with COPD. Methods Forty patients with type 2 respiratory failure who were hospitalized between June and December 2018 with the diagnosis of COPD exacerbations were included to the study. Patients followed up without NIMV for 12 hours after the end of exacerbations treatments end. After IOP, visual acuity and CCT were measured in all patients at the same time (11.00 am), same NIMV treatment was applied to the patients for 4 hours (AVAPS-BPAP S/T). Then the measurements were repeated. The effects of these NIMV modes on IOP were evaluated. Results After NIMV treatment, it was observed that the mean IOP increased statistically significantly (13.3 vs 12.3 mm Hg; P = 0.001). After treatment with NIMV, there was a decrease for CCT close to statistical significance (P = 0.057) Conclusion As a result; increased IOP and thinning of CCT after NIMV treatment has been shown. The type of NIMV and the level of inspiratory pressure needed in hypercapnic respiratory failure seem to affect IOP and it should be cautiously used to increase IOP.Öğe The effects of subconjunctival bevacizumab, ranibizumab, and aflibercept on corneal neovascularization(Sage Publications Ltd, 2022) Eski, Mehmet Tahir; Teberik, Kuddusi; Oltulu, Pembe; Ankaralı, Handan; Kaya, Murat; Alpay, MervePurpose To investigate the effects of subconjunctival bevacizumab, ranibizumab, and aflibercept in an experimental corneal neovascularization model. Materials and methods The eyes of 24 rats were chemically cauterized and randomly divided into four groups: bevacizumab group (0.05 mL/1.25 mg bevacizumab), ranibizumab group (0.05 mL/0.5 mg ranibizumab), aflibercept group (0.05 mL/1.25 mg aflibercept), and control group (0.05 mL saline solution). Plasma vascular endothelial growth factor (VEGF) levels were among the major measurement outcomes to assess corneal neovascularization. The collected plasmas were analyzed using the SIGMA RAB0511 Rat VEGF Elisa kit. The PCR technique and VEGF amplification procedures were used for molecular analysis. Each cornea was removed and histologically examined on day 21. Corneal images were evaluated by image analyzer software. Results In the post-injection period, the number of major corneal arteries decreased significantly in the injection groups when compared to the control group (p = 0.037), but no statistically significant differences were noted among the injection groups (p > 0.05). The aflibercept group had the lowest area of neovascularization. Immunohistochemical staining revealed substantially lower VEGF percentages in neovascularized arteries of the injection groups than the control group (p = 0.015). In TUNEL staining, the mean TUNEL value (number/1hpf) was substantially greater in the control group than in the injection groups, but the mean TUNEL values were similar between the injection groups (p = 0.019, p > 0.05, respectively). No statistically significant differences were observed between the groups in terms of corneal surface area with increased cellularity, edema, and inflammation (p = 0.263). The mean plasma VEGF concentration in the control group was statistically greater than those in the injection groups (p = 0.001). Conclusion Subconjunctival bevacizumab, ranibizumab, and aflibercept crossed the blood and seemed to be effective in inhibiting corneal neovascularization without causing epitheliopathy in an experimental rat model compared to the controls. However, no significant results were noted between these three anti-VEGF molecules.Öğe The Effects of Swimming Goggles on Intraocular Pressure in Children(Kamla-Raj Enterprises, 2015) Teberik, Kuddusi; Karacabey, Kürşat; Sağlam, Hakan; Özbar, Nurper; Karadenizli, İnci; Özmerdivenli, Recep; Kaya, MuratThe aim of this study is to evaluate the effects of wearing swimming goggles on intraocular pressure in children. The study comprises of 20 eyes from 10 children, 4 male (40%) and 6 female (60%). The median age was 10.4 with a range of 9 to 11 years (mean age was 10.4). Before the study, the height (cm), weight (kg) and intraocular pressure values of children were measured by using two different appliances. Upon the durations of stay in water, 3 different periods were set at 5 minutes, 10 minutes and 20 minutes. Two different eye doctors measured intraocular pressure values of children with specified appliances after the end of each period and then immediately after the goggles were taken off. The average height of the children was 146.5cm ranging from 140 to 163 cm and the average weight was 42.84kg ranging from 33 to 51.6 kg. Before the goggles were worn, the average intraocular pressure value was measured at 16.5 ranging from 12 to 23 mmHg with a tono-pen and at 16.3 ranging from 11 to 22 mmHg with a non-contact tonometer for the right eye, while it was 16.6 ranging from 11 to 21 mmHg with a tono-pen and 16.2 ranging from 11 to 21mmHg with non-contact tonometer for the left eye. At the end of the first period (after 5 minutes), the average intraocular pressure value of right eye was 17.2 (12-23) mmHg measured with a tono-pen and 16.8 (12-23) mmHg measured with a non-contact tonometer, at the end of second period values were 17.0 (10-23) mmHg and 17.3 mmHg, respectively, at the end of the third period the values were 17.30 (13-24) mmHg and 17.60 (12-24) mmHg, respectively. The average intraocular pressure values of the left eye were 16.7 (11-22) mmHg and 16.3 (10-24) mmHg, respectively, at the end of second period values were 16.7 (1025) mmHg, 16.6 (11-23) mmHg, respectively, and at the end of the third period the values were 17.70 (13-24), 17.10 (12-23) mmHg, respectively. The researchers considered that patients with glaucoma and suspected glaucoma should use well fitting swimming goggles, which do not have overly tightened straps and a small rim diameter.Öğe Effects of topical azithromycin, moxifloxacin, and povidone iodine on conjunctival bacterial flora in patients undergoing intravitreal injection(Consel Brasil Oftalmologia, 2019) Teberik, Kuddusi; Eski, Mehmet Tahir; Çalışkan, Emel; Kılınçel, Özge; Kaya, Murat; Ankaralı, HandanPurpose: To compare effects of 5% topical povidone iodine with prophylactic topical azithromycin and moxifloxacin on bacterial flora in patients undergoing intravitreal injection. Methods: A total of 132 patients were randomly assigned to receive treatment with azithromycin or moxifloxacin, or no treatment (control group). In total, 528 specimens were obtained at the time of admission, 4 days before intravitreal injection, 4 days after intravitreal injection, and 8 days after intravitreal injection. Samples were immediately sent to the microbiology laboratory for incubation. Results: The microorganism observed most frequently was coagulase-negative Staphylococcus (23.8%). When the results of samples obtained on Day 4 before injection were assessed, growth of coagulase-negative Staphylococcus was significantly lower in the moxifloxacin group, compared with controls (p=0.049). Acinetobacter baumannii continued to grow after administration of azithromycin (p=0.033). When the results of four days after intravitreal injection were evaluated, growth of coagulase-negative Staphylococcus was higher in controls, compared with patients who received azithromycin or moxifloxacin (p=0.004). Eradication rate was significantly higher in the moxifloxacin group than in the control group (p=0.001). Samples obtained on Day 8 after intravitreal injection showed similar levels of bacterial growth in all groups (p=0.217). Conclusion: Moxifloxacin was more effective than 5% povidone iodine in controlling the growth of conjunctival bacterial flora. Use of moxifloxacin in combination with 5% povidone iodine resulted in a synergistic effect.Öğe End-tidal carbon dioxide levels under surgical drapes during local eye surgery: Retrospective study(Kuwait Medical Association, 2022) Yorulmaz, İlknur Suidiye; Esbah, A.U.; Ozlu, O.; Teberik, Kuddusi; Sözer, M.U.; Kaya, M.Objectives: To investigate the end tidal carbon dioxide pressure values in order to determine carbon dioxide accumulation under surgical drapes and it’s hemodynamic effects based on anesthetic and surgical records in eye surgeries under local anesthesia Design: Retrospective study Setting: Department of Anesthesiology and Reanimation, Düzce Medical Faculty, Düzce, Turkey Subject: The data were collected from anesthetic records of patients (n=42) who were followed with noninvasive capnography in the operating room at Düzce University Hospital during the period of January 2016 to December 2016. Systolic, diastolic and mean arterial pressure, operation time, heart rate, ST segment analysis, ETCO2 pressure, pulse oximetry values ??were recorded. Time periods were determined as: after the anesthesia and before drape closure (baseline level), at 10t h, 15th, 20th, 45th of the surgery and 5 minutes after drape removal. Intervention: Non-interventional Main outcome measure: C a rbon dioxide accumulation under drapes and it’s hemodynamic effects in eye surgeries under local anesthesia. Results: The comparisons were made with basal status and time periods statistically. No differences were found between mean arterial pressures, heart rates, arrhythmias and pulse oximetry values of pati ents between time periods. We observed significant di fferences for ETCO2 levels between basal and the other ti me periods, except when the drapes were removed (P=0.001). Conclusion: Routine mo nitorisation of ETCO2 with noninvasive capnograph yprovides early detection of CO2 accumulation and CO2 rich air breathing during ophthalmic surgery. © 2022, Kuwait Medical Association. All rights reserved.Öğe End-tidal carbon dioxide levels under surgical drapes during local eye surgery: Retrospective study(Kuwait Medical Assoc, 2022) Yorulmaz, Ilknur Suidiye; Esbah, Ali Umit; Ozlu, Onur; Teberik, Kuddusi; Sozer, Muhammet Uzeyir; Kaya, MuratObjectives: To investigate the end tidal carbon dioxide pressure values in order to determine carbon dioxide accumulation under surgical drapes and it's hemodynamic effects based on anesthetic and surgical records in eye surgeries under local anesthesia Design: Retrospective study Setting: Department of Anesthesiology and Reanimation, Duzce Medical Faculty, Duzce, Turkey Subject: The data were collected from anesthetic records of patients (n=42) who were followed with noninvasive capnography in the operating room at Duzce University Hospital during the period of January 2016 to December 2016. Systolic, diastolic and mean arterial pressure, operation time, heart rate, ST segment analysis, ETCO2 pressure, pulse oximetry values were recorded. Time periods were determined as: after the anesthesia and before drape closure (baseline level), at 10th, 15th, 20th, 45th of the surgery and 5 minutes after drape removal. Intervention: Non-interventional Main outcome measure: Carbon dioxide accumulation under drapes and it's hemodynamic effects in eye surgeries under local anesthesia. Results: The comparisons were made with basal status and time periods statistically. No differences were found between mean arterial pressures, heart rates, arrhythmias and pulse oximetry values of patients between time periods. We observed significant differences for ETCO2 levels between basal and the other time periods, except when the drapes were removed (P=0.001). Conclusion: Routine monitorisation of ETCO2 with noninvasive capnography provides early detection of CO2 accumulation and CO2 rich air breathing during ophthalmic surgery.Öğe Evaluation of Anterior Segment Parameters and Retinal Nerve Fiber Layer Thickness According to Pregnancy Trimester(Duzce Univ, 2018) Teberik, Kuddusi; Başbuğ, Alper; Sağlam, Hakan; Karaaslan, Musa; Kaya, MuratObjective: To analyze the effects of pregnancy on anterior segment parameters and retinal nerve fiber layer (RNFL) thickness. Methods: The study designed prospectively conducted among 122 singleton pregnant women and 49 non-pregnant women. Intraocular pressure (IOP) was measured via the Goldman applanation tonometry. Central corneal thickness (CCT), axial lenght (AxL) and anterior chamber depth (ACD) measurement were performed with Echoscan US 500. For investigating the thickness of RNFL in detail, the optical coherence tomography was used. One Way ANOVA test was used to make a comparison between normal distribution groups. Results: There was no statistically significant difference regarding age. The IOP were 16.0 mmHg in the 1st trimester, 14.6 mmHg in the 2nd trimester, 13.6 mmHg in the 3rd trimester and 15.56 mmHg in the non-pregnant. Statistically, the findings of the 2nd and the 3rd trimester were significantly different from that of the 1st trimester (p = 0.033, p = 0.001, respectively). CCT averages were 554 mu m, 564 mu m and 552 mu m, respectively, according to the trimester, while it was 542 mu m in non-pregnant women. The difference between CCT averages between pregnancies in the 2nd and 3rd trimesters and non-pregnant women was statistically significant (p = 0.022, p = 0.041, respectively). The comparison of average thickness of four RNFL showed no difference between the pregnant and non-pregnant. Conclusions: During gestation, there was an increase in CCT with a decrease in IOP. We also determined that the ACD, AxL, and RNFL thickness measurements do not change with pregnancy.Öğe Evaluation of Intraocular pressure, Corneal thickness, and Retinal nerve fiber layer thickness in patients with Obstructive Sleep Apnea Syndrome(Professional Medical Publications, 2018) Teberik, Kuddusi; Eski, Mehmet Tahir; Balbay, Ege Güleç; Kaya, MuratObjective: To evaluate the intraocular pressure (IOP), central corneal thickness (CCT), and peripapillary retinal nerve fiber layer (RNFL) thickness in Patients with Obstructive Sleep Apnea Syndrome. Methods: In this prospective study, 103 patients with OSAS (study group) and 37 healthy subjects were enrolled. All participants underwent comprehensive ophthalmic examinations. Mean outcome measures were intraocular pressure by Goldmann applanation tonometry, CCT measurement using ultrasound pachymeter and peripapillary RNFL thickness measured by spectral-domain optical coherence tomography. Results: The differences between the mean values of RNFL thickness in all quadrants were similar in both groups and were not statistically significant (p=0.274). The IOP and CCT measurement averages of all patients with OSAS were lower than the control group. However, this difference was not statistically significant. There was no correlation between the apnea-hypopnea index, lowest oxygen saturation (LAST) or Body Mass Index (BMI) and the peripapillary RNFL thickness, IOP or CCT when OSAS group was divided by severity. Conclusions: The study results suggest that peripapillary RNFL thickness, IOP or CCT did not differ significantly between OSAS and control groups. We also found no correlation between apnea severity (AHI), lowest oxygen saturation (LAST) and BMI and RNFL, CCT and IOP.Öğe Evaluation of ocular findings in patients with lichen planus(Termedia Publishing House Ltd, 2019) Özlü, Emin; Teberik, KuddusiIntroduction: Lichen planus (LP) is a chronic, inflammatory disease of unknown etiology. Aim: To evaluate the tear functions and the retinal and choroidal thickness (CT) in patients with LP. Material and methods: In total, 33 patients and 30 healthy controls were enrolled. All participants were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer 1 test (with anesthesia), tear break-up time (TBUT) test, intraocular pressure (IOP), axial length (AL), and central corneal thickness (CCT). The measurements of retinal thickness (RT) and CT were obtained by spectral domain optical coherence tomography. Results: No significant difference was observed between the groups in IOP, AL, CCT, or RT (p > 0.05 in each group). There was a significant difference in the Schirmer 1 test, TBUT, and OSDI questionnaire (p < 0.05 in each group). Choroidal thickness in LP patients was thinner than that in the controls (p = 0.001 in each location). There was a moderate negative correlation between the disease duration and Schirmer 1 test, TBUT, and subfoveal CT (r = -0.426, r = -0.555, r = -0.637; p = 0.001, p = 0.001, p = 0.001, respectively). There was a moderate negative correlation between the oral mucosal involvement and Schirmer 1 test, TBUT, and subfoveal CT (r = -0.345, r = -0.392, r = -0.467; p = 0.006, p = 0.001, p = 0.001, respectively). There was a positive correlation between disease duration, oral mucosal involvement and OSDI score (r = 0.717, r = 0.345; p = 0.001, p = 0.006, respectively). Conclusions: Lichen planus may influence tear function tests and may cause dry eye. Patients with LP had lower CT values than healthy controls. Further studies are needed to clarify the effect of LP on the eyes.
