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    Assessment of Central Corneal Thickness, Intraocular Pressure and Retinal Nerve Fiber Layer Thickness at Women with Polycystic Ovary Syndrome
    (Duzce Univ, 2017) Teberik, Kuddusi; Sağlam, Hakan; Başbuğ, Alper; Karaaslan, Musa; Kaya, Murat; Sungur, Mehmet Ali
    Objective: To compare intraocular pressure, central cornea thickness, anterior chamber depth, axial length and thickness of retina nerve fiber layer between women with polycystic ovary syndrome and healthy at the same age segment. Methods: Between August 2015-January 2016, 46 women who have polycystic ovary syndrome and 53 healthy women have been included to the study. After a complete ophthalmologic examination, intraocular pressure, central cornea thickness, anterior chamber depth, axial length and retinal nerve fiber layer thickness were investigated. In the statistical analysis of the data, Independent Samples t test was utilized to compare the groups. Results: While mean age was 23.4 +/- 4.5 (16-35) in the group with polycystic ovary syndrome, average age level was found as 24.0 +/- 6.1 (18-54) among the controls (P=0.549). Intraocular pressure values were measured and determined as 17.7 +/- 2.6 mmHg in the group with polycystic ovary syndrome, while the values were 15.2 +/- 2.4 mmHg in the controls (P <0,001). Although it was 79.4 +/- 10.2 mu m in the group with polycystic ovary syndrome, retinal nerve fiber layer thickness in the nasal quadrant was found to be 73.8 +/- 10.9 mu m among the controls (P <0.001). Conclusion: We found that the increased levels seen in intraocular pressure and retinal nerve fiber layer thickness in the nasal quadrants of the patients with polycystic ovary syndrome were statistically significance. Hence, we recommend that the patients with polycystic ovary syndrome should be specially analyzed as to eye assessment.
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    Evaluation of Anterior Segment Parameters and Retinal Nerve Fiber Layer Thickness According to Pregnancy Trimester
    (Duzce Univ, 2018) Teberik, Kuddusi; Başbuğ, Alper; Sağlam, Hakan; Karaaslan, Musa; Kaya, Murat
    Objective: To analyze the effects of pregnancy on anterior segment parameters and retinal nerve fiber layer (RNFL) thickness. Methods: The study designed prospectively conducted among 122 singleton pregnant women and 49 non-pregnant women. Intraocular pressure (IOP) was measured via the Goldman applanation tonometry. Central corneal thickness (CCT), axial lenght (AxL) and anterior chamber depth (ACD) measurement were performed with Echoscan US 500. For investigating the thickness of RNFL in detail, the optical coherence tomography was used. One Way ANOVA test was used to make a comparison between normal distribution groups. Results: There was no statistically significant difference regarding age. The IOP were 16.0 mmHg in the 1st trimester, 14.6 mmHg in the 2nd trimester, 13.6 mmHg in the 3rd trimester and 15.56 mmHg in the non-pregnant. Statistically, the findings of the 2nd and the 3rd trimester were significantly different from that of the 1st trimester (p = 0.033, p = 0.001, respectively). CCT averages were 554 mu m, 564 mu m and 552 mu m, respectively, according to the trimester, while it was 542 mu m in non-pregnant women. The difference between CCT averages between pregnancies in the 2nd and 3rd trimesters and non-pregnant women was statistically significant (p = 0.022, p = 0.041, respectively). The comparison of average thickness of four RNFL showed no difference between the pregnant and non-pregnant. Conclusions: During gestation, there was an increase in CCT with a decrease in IOP. We also determined that the ACD, AxL, and RNFL thickness measurements do not change with pregnancy.
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    Polikistik Over Sendromlu Kadınlarda Santral Kornea Kalınlığı, Göz İçi Basıncı ve Retinal Sinir LifiTabakası Kalınlığının Değerlendirilmesi
    (2017) Teberik, Kuddusi; Sağlam, Hakan; Başbuğ, Alper; Karaaslan, Musa; Kaya, Murat; Sungur, Mehmet Ali
    Amaç: Aynı yaş segmentinde polikistik over sendromlu ve sağlıklı kadınlar arasındaki göz içi basıncı, santral kornea kalınlığı, ön kamara derinliği, aksiyel uzunluk ve retina sinir lifi tabakası kalınlığını karşılaştırmak. Yöntem: Ağustos 2015-Ocak 2016 tarihleri arasında 46 polikistik over sendromlu ve 53 sağlıklı olmak üzere toplam 99 kadın çalışmaya dahil edildi. Tam bir oftalmolojik muayeneden sonra göziçi basıncı, santral kornea kalınlığı, ön kamara derinliği, aksiyel uzunluk ve retina sinir lifi tabakası kalınlığı ölçümleri yapıldı. Verilerin istatistiksel olarak değerlendirilmesinde grupların karşılaştırılması amacıyla Independent Samples t test kullanıldı. Bulgular: Polikistik over sendromlu grupta yaş ortalaması 23.4 4.5 iken, kontrol grubunda 24.0 6.1 (18.54) olarak bulundu (p 0.549). Polikistik over sendromlu grupta ortalama göz içi basıncı değeri 17.7 2.6 mmHg ve kontrol grubunda 15.2 2.4 mmHg olarak bulundu (P 0.001). Nazal kadrandaki retina sinir lifi kalınlığı polikistik over sendromlu grupta 79.4 10.2 mikron iken kontrol grubunda 73.8 10.9 mikrondu (P 0.001). Sonuç: Polikistik over sendromlu hastaların nazal kadrandaki retina sinir lifi tabakası kalınlığı ve göz içi basıncında görülen artmış düzeylerin istatistiksel olarak anlamlı olduğu bulundu. Bu nedenle, polikistik over sendromlu hastaların göz muayenesi açısından yakından değerlendirilmesini önermekteyiz.