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Öğe Assessment of physical function, quality of life, and medication adherence in elderly patients with rheumatic diseases(Springernature, 2021) Erdem Sultanoğlu, Tuba; Ataoğlu, Safinaz; Avşar, Burcu; Merkur, Ömer FarukBackground The proportion of older people in the total population has increased in Turkey as well as worldwide. As life expectancy rises, the increasing prevalence of rheumatic diseases poses major problems in the elderly. Comorbid diseases and the aging-induced changes in the endogenous immune response and the pharmacokinetic properties of therapeutic agents may complicate the decision to use a particular drug and result in a different clinical picture and treatment response. We, therefore, aimed to investigate the characteristics of chronic inflammatory diseases, their impact on physical function and quality of life, the prevalence of comorbid diseases that may complicate treatment planning, and treatment adherence in patients aged 65 years or older. Results One hundred seventy-four patients were included and divided into two age groups: 18-64 years (group 1, n = 85) and 65 years or older (group 2, n = 89). The mean age of all recruited patients was 57.55 +/- 16.98 years. Of 174, 99 (56.9%) were female and 75 (43.1%) were male. The mean duration of rheumatic disease was 7 +/- 4.8 years and age at onset was 51.46 +/- 14.78 years. Gender distribution differed significantly by age group (P = 0.024). The percentage of females in group 1 was 48.2% and 65.2% in group 2. The occupational status also differed significantly by age group (P < 0.001). 48.2% of group 1 were employed and 57.3% of group 2 were housewives. Marital status varied significantly by age (P < 0.001). The percentage of married was 74.1% in group 1 and the percentage of separated/divorced/widowed in group 2 was 28.1%. There was no difference between groups 1 and 2 in terms of place of residence (P = 0.459). The prevalence of comorbid diseases and the rate of use of medications for comorbid diseases (non-rheumatic treatments) were higher in elderly patients. The rate of use of disease-modifying anti-rheumatic drugs (DMARDs) was 30.3% and biological agents 61.8% in the elderly group (>= 65 years) (group 2) (P < 0.001). There were positive correlations between, Health Assessment Questionnaire (HAQ), Bath Ankylosing Spondylitis Functional Index (BASFI) and Nottingham Health Profile (NHP) domains in both groups. There was also a significant negative correlation between Medication Adherence Rating Scale (MARS) and all dimensions. Conclusions Elderly and younger patients with rheumatic diseases have different demographic and clinical characteristics. Physical function and quality of life are more affected by rheumatic diseases and treatment adherence is poorer in the elderly. Our study found a positive correlation between physical function and quality of life in both age groups. The treatment adherence rating scale showed a negative correlation with physical function and quality of life scores, with individuals with poor treatment adherence having worse physical function and quality of life.Öğe Lumbar radiculopathy(Nova Science Publishers Inc., 2025) Erdem Sultanoğlu, TubaLow back pain is one of the most common musculoskeletal complaints in clinical practice. The differential diagnosis of low back pain is broad and should include lumbosacral radiculopathy. Radiculopathy is a term that covers sensory and motor deficits and paresthetic complaints resulting from the pathology of the nerve roots. Lumbar radicular pain is neuropathic pain caused by disc compression of the lumbar spinal nerve root, resulting in radiating pain in a dermatomal pattern. The most common causes of radicular pain are intervertebral disc herniation and lumbar spinal stenosis. Diseases such as neoplasms affecting the nerve roots, epidural abscesses, Herpes zoster, and Lyme disease can also cause radicular pain. The diagnosis of lumbar radicular pain due to disc compression/stenosis can be made by a history and physical examination. However, imaging and electrodiagnostic studies should be performed to exclude other possible causes of radicular symptoms. Urgent imaging and rapid intervention are important if 'red flag' symptoms or signs such as cauda equina syndrome, malignancy, vertebral fracture, vertebral osteomyelitis, and epidural abscess are present. Conservative treatment is the first-line treatment for radicular pain. However, in the presence of progressive neurologic deficit or cauda equina syndrome following radicular pain, surgical planning should be made according to the etiology and the current condition of the patient. © 2025 Elsevier B.V., All rights reserved.Öğe Prognosis and recovery after stroke(Nova Science Publishers, Inc., 2024) Erdem Sultanoğlu, TubaStroke is a cause of disability with controllable risk factors, increasing mortality and morbidity. There are many restorative treatment modalities that focus on supporting plasticity in regions of the brain recovered from acute damage in survivors, where reperfusion is provided by acute treatments after stroke. Although neurological recovery after a stroke occurs mostly in the first three months, recovery continues slowly for the first 1-2 years. Recovery from stroke occurs in different processes. Depending on the initial damage, neurological recovery begins in the first weeks with the disappearance of pathologies such as ischaemia, metabolic damage, oedema, haemorrhage, and compression. Even in patients with extensive damage to the primary motor area, the acquisition of new functions by neighbouring areas or distant brain regions that have not been damaged plays a role in the recovery process. The neuroplastic reorganisation involves the repair of damaged pathways and the involvement of other neurons to perform new functional functions. Spontaneous recovery after a stroke is usually not complete, and recovery rates are variable. Motor recovery is rapid in the early period. Most motor function gains occur in the first 3 months after stroke and continue until the 6th month. © 2024 Elsevier B.V., All rights reserved.Öğe Radiologic abnormalities of pelvic area and clinical outcomes in patients with femoroacetabular ımpingement syndrome(Mersin University, 2021) Erdem Sultanoğlu, Tuba; Ataoğlu, Sarfinaz; Altınsoy, Hasan Baki; Sultanoğlu, HasanAim: In our study, we aimed to examine the clinical outcomes and radiological changes in the pelvic region in patients with femoroacetabular impingement syndrome; to emphasize the importance of femoroacetabular impingement in the etiology of hip pain and conservatif management. Material and Methods: The sociodemographic and clinical characteristics, abdominal and pelvic computed tomography scans, pelvic magnetic resonance imaging of 104 patients diagnosed with femoroacetabular impingement syndrome between August 2016-August 2020 were retrospectively analyzed.Results: 41.3% of the patients were female, 58.7% were male and the mean age was 52.78 ± 13.18. 37.5% of the patients are housewives; 29.8% are not working; 28.8% were working and 3.8% were students. The proportion of patients with hip pain was 76%. 31.7% had pain in the right hip; 22.1% had pain in the left hip and 22.1% in both hip regions. Activity modification and medical therapy for 17.3% of the patients; medical treatment and home exercise program in 32.7%; physiotherapy was applied in 26.0%; no treatment was applied in 24.0%. 54.8% of the patients were diagnosed by tomography and 45.2% of them were diagnosed by magnetic resonance imaging. According to radiological results, 80.8% of them had cam; 5.8% had pincer and 13.5% had mixed type of femoroacetabular impingement. In 53.7% of asymptomatic patients and in 61.8% of the patients with pain complaints had additional radiological changes in the pelvic region. Accompanying radiological changes in the pelvic region were mostly subcortical cysts and sclerosis. Conclusion: Femoroacetabular impingement syndrome, which is one of the important factors in the development of hip osteoarthritis, should be considered when investigating the causes of hip pain. Protection of the hip joint and increasing the patient's quality of life should be aimed with early diagnosis and effective treatment. For these purposes, physiotherapy can be considered as a treatment option in patients with symptomatic femoroacetabular impingement syndrome












