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Öğe Absence of the epiglottis in an infant with pierre robin sequence(Elsevier Ireland Ltd, 2011) Güven, Damla Güçlü; Şenses, Dursun Ali; Subaşı, Buğra; Yaman, HüseyinEpiglottis anomaly associated with Pierre Robin sequence (PRS) is a rare occurrence. Most infants with PRS have presented life-threatening symptoms of respiratory distress and severe feeding problems that usually end with death. To the knowledge of the authors, this is the first reported case of epiglottis agenesis associated with PRS. The clinician must be aware of this unusual presentation in a PRS, and the presented case reveals the challenges in the treatment of the respiratory and feeding problems. This case is discussed with a review of the literature. © 2010 Elsevier Ireland Ltd. All rights reserved.Öğe Batı karadeniz bölgesinde çocukluk çağı zehirlenmelerinin retrospektif değerlendirilmesi(2007) Uzun, Hakan; Mindan, Gültekin; Şenses, Dursun Ali; Şimşek, Enver; Kocabay, KenanZehirlenmeye yol açan etkenler yaşanılan bölgeye, toplumun gelenek ve göreneklerine, ailenin eğitim düzeyine ve mevsimlere göre değişkenlik gösterebilir. Bu çalışmanın amacı, hastanemizde son iki yıl içinde yatırılarak tedavi edilen zehirlenme vakalarını gözden geçirmektir. Yöntem: Ocak 2003-aralık 2005 tarihleri arasında hastanemizde entoksikasyon tanısı alan yüz on dört hasta retrospektif olarak değerlendirildi. Bulgular: Zehirlenmeler en çok 1-5 yaş grubunda (% 78.9) gözlendi. Erkek/kız oranı 1.23’tü. Zehirlenmelerin en fazla sonbahar mevsiminde (% 28.1) olduğu görüldü. Zehirlenmeye neden olan etkenler sıklıkla ilaçlardı (% 50.9). En sık antipsikotikler ve analjezik-antipretik ilaçların alımı söz konusuydu. Sonuç: Zehirlenmelerin tedavisinde önemli gelişmeler olmakla birlikte, bu sorunun çözümünde en etkin yöntem koruyucu önlemlerin alınmasıdır.Öğe CONGENITAL IMPERFORATE HYMEN WITH BILATERAL HYDRONEPHROSIS, POLYDACTYLY AND LARYNGOCELE: A Rare Neonatal Presentation(Taylor & Francis Inc, 2010) Öztürk, Hülya; Yazıcı, Burhan; Küçük, Adem; Şenses, Dursun AliImperforate hymen is a rare congenital malformation to present with symptoms in the neonatal period. We present a case of a 5-day-old neonate with a marked interlabial swelling causing urinary retention. Imaging revealed hydrometrocolpos, hydrosalpinx, and bilateral hydronephrosis. Additionally, our patient had polydactyly of both feet and hands, and laryngocele that have not been previously described in literature. Hymenectomy is the mainstay of management to prevent the development of hematocolpos, pain, and possible retrograde menstruation.Öğe Deli bal zehirlenmesine bağlı bradikardi ve hipotansiyon gelişen çocuk olgusu(2013) Uzun, Hakan; Sarı, İlyas; Güneş, Cemalettin; Kocabay, Kenan; Şenses, Dursun Ali; Kandiş, HayatiDeli bal zehirlenmesi Türkiyenin Karadeniz Bölgesinde görülen bir durumdur. Bu zehirlenmenin nedeni, bölgedeki dağlarda doğal olarak yetişen Rhododendron ponticum bitki türünün nektarından elde edilen balda bulunan, grayanotoksin diye bilinen toksinden kaynaklanır. Burada, bal yedikten sonra kan basıncı düşüklüğü ve bradikardi nedeniyle gelişen halsizlik ve baş dönmesi yakınmaları ile acil servise getirilen 15 yaşındaki bir erkek çocuk sunuldu. (Türk Ped Arfl 2013; 48: 53-4)Öğe Do gastrointestinal and respiratory signs and symptoms correlate with the severity of gastroesophageal reflux?(2012) Uzun, Hakan; Alagöz, Demet; Okur, Mesut; Dikici, Bünyamin; Kocabay, Kenan; Şenses, Dursun Ali; Kaya, MuratBackground: Gastroesophageal reflux (GER) is a disorder that is common by seen in childhood and may lead to severe complications. In this study, we ascertained the incidence of GER among the children who had typical and atypical complaints of GER and whether there was a difference between two groups comparing the findings of 24-hour pH-meter.Methods: 39 out of 70 patients with typical and atypical GER symptoms were diagnosed as GER by 24-hour pH-meter monitoring. The patients were divided into three groups, those having gastrointestinal complaints, those having respiratory complaints and those having both gastrointestinal and respiratory symptoms.Results: Evaluated the GER prevalence in these groups, it was found to be 60% in the gastrointestinal group, 48.6% in the respiratory group and 75% in the mixed group. When pH-meter measurements of GER positive patients were compared within the clinical groups, the fraction of time that pH was lower than 4 was found to be significantly higher in the mixed group (p = 0.004).Conclusions: The coexistence of gastrointestinal and respiratory symptoms in the patients with GER may be related to the severe reflux. © 2012 Uzun et al; licensee BioMed Central Ltd.Öğe EEC SYNDROME WITH A DE NOVO MUTATION (c.953G > A) ON EXON 7 OF P63 GENE: A CASE REPORT(Medecine Et Hygiene, 2012) Okur, Mesut; Eröz, Recep; Mundlos, Stefan; Şenses, Dursun Ali; Ülgen, E.; İsmailler, Z.B.; Özçelik, DeryaEEC syndrome with a de novo mutation (c.953G>A) on exon 7 of p63 gene: a case report: EEC syndrome is characterized by ectodermal dysplasia, ectrodactyly and cleft lip and/or palate and associated anomalies such as lacrimal duct obstruction, urinary tract anomaly, and hearing loss. This syndrome is a rare autosomal dominant disorder caused by heterozygous mutations in the p63 gene. Herein, a newborn infant with EEC syndrome with secundum atrial septal defect who had a de novo mutation (c.953G>A) on exon 7 of p63 gene is presented.Öğe EEC syndrome with a de novo mutation (c.953G>A) on exon 7 of p63 gene: A case report(2012) Okur, Mesut; Eröz, Recep; Mundlos, Stefan; Şenses, Dursun Ali; Ülgen, E.; İsmailler, Z.B.; Özçelik, DeryaEEC syndrome is characterized by ectodermal dysplasia, ectrodactyly and cleft Hp and/or palate and associated anomalies such as lacrimal duct obstruction, urinary tract anomaly, and hearing loss. This syndrome is a rare autosomal dominant disorder caused by heterozygous mutations in the p63 gene. Herein, a newborn infant with EEC syndrome with secundum atrial septal defect who had a de novo mutation (c.953G>A) on exon 7 of p63 gene is presented.Öğe Lateral facial cleft associated with accessory mandible having teeth, absent parotid gland and peripheral facial weakness(Churchill Livingstone, 2014) Özçelik, Derya; Toplu, Gaye; Türkseven, Arzu; Şenses, Dursun Ali; Yiğit, BüşraTransverse facial cleft is a very rare malformation. The Tessier no. 7 cleft is a lateral facial cleft which emanates from oral cavity and extends towards the tragus, involving both soft tissue and skeletal components. Here, we present a case having transverse facial cleft, accessory mandible having teeth, absent parotid gland and ipsilateral peripheral facial nerve weakness. After surgical repair of the cleft in 2-month of age, improvement of the facial nerve function was detected in 3-year of age. Resection of the accessory mandible was planned in 5-6 years of age. (C) 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.Öğe Neonatal Graves' disease occurring in an infant whose mother had a thyroidectomy due to Graves' disease [Graves hastali?i nedeniyle tiroidektomi olan annenin yenido?an bebe?inde Graves hastali?i: Bir vaka takdimi](Cocuk Sagligi ve Hastaliklan Dergisi, 2015) Bolu, Semih; Karakaşlı, Özlem; Ay, Oğuzhan; Soysal, Zeyneb; Şenses, Dursun Ali; Arslanoğlu, İlknurNeonatal Graves' disease caused by fetal thyroid gland stimulation is the result of transplacental passage of maternal thyroid-stimulating hormone receptor antibodies in the second trimester of pregnancy. A mother with Graves-Basedow disease had a total thyroidectomy operation three months before a pregnancy; maternal TSH receptor antibody (TRAb) were detected at the sixth month of pregnancy. Antithyroid drug therapy was started to the 34 weeks' gestational age infant, who was diagnosed with neonatal hyperthyroidism. The condition improved after five weeks of antithyroid therapy. The pathogenesis was believed to be due to transplacental passage of maternal TRAb. This case is presented to highlight the fact that even mothers who have a total throidectomy for Graves' disease may have infants with rarely seen neonatal Graves' disease due to the presence of maternal TRAb in the circulation.Öğe The prevalence of overweight and obese children aged 6-17 years in the West Black Sea region of Turkey(Wiley, 2008) Şimşek, Enver; Akpınar, S.; Bahçebaşı, Talat; Şenses, Dursun Ali; Kocabay, KenanObjective: To assess the prevalence of overweight and obese Turkish children. Design: Cross-sectional study in school children. Subjects: A total of 6924 children (3281 boys and 3643 girls) aged 6-17 years from the West Black Sea region of Turkey. Measurements: Overweight and obese were defined using international age- and sex-specific cutoff points for body mass index. The data were analysed by age, sex, residence and socioeconomic level. Results: The overall prevalence of overweight and obesity was 10.3% and 6.1% respectively. The overall prevalence of obesity in boys and girls was 7.0% and 5.4%, respectively, and the difference was significant (chi(2) = 8, p = 0.004). The prevalence of obesity in urban and rural areas was 7.7% and 3.9%, respectively, and the difference was significant (chi(2) = 40, p < 0.001). The prevalence of overweight boys and girls in urban areas was 11.6% and 13.2%, respectively, but the difference was not significant (chi(2) = 2, p > 0.05). However, the prevalence of overweight boys and girls in rural areas was 4.8% and 9.4%, respectively, and the difference was significant (chi(2) = 25, p < 0.001). Although the prevalence of obesity differed significantly between boys and girls in urban children (chi(2) = 13, p < 0.001), no significant difference was detected in the prevalence between boys and girls from rural areas (chi(2) = 0.4, p > 0.5). The prevalence of obesity was significantly higher in private schools than in public schools (chi(2) = 48, p < 0.0001). The prevalence of overweight and obese Turkish children aged 6-17 years is considerably lower than in most European countries. The children in urban settings and higher socioeconomic groups had a higher prevalence of overweight and obesity. The Westernisation of the behaviour patterns of children and living in an urban setting in a developing country are risk factors for obesity.Öğe Psödo Bartter sendromu: Bir olgu sunumu(2011) Okur, Mesut; Otlu, Ayşenur; Şenses, Dursun Aliİki gündür akciğer enfeksiyonu yakınmaları olan 7.5 aylık kız hasta, konvülsiyon nedeniyle acil polikliniğimize getirildi. Yoğun bakım ünitesindeki izlemi sırasında hiponatremi, hipokalemi, hipokloremi ve metabolik alkalozu saptanan hastaya psödo Bartter sendromu tanısı konuldu. İntravenöz sıvı ve uygun defisit tedavileriyle genel durumu, elektrolit bozukluğu ve alkalozu düzeldi. Ter testi sonucu 120 mEq/L bulunan hasta bir kistik fibrozis hastası olarak izleme alındı.Öğe A rare cause of neonatal hypocalcemia: malignant infantile osteopetrosis(Tubitak Scientific & Technical Research Council Turkey, 2009) Uzun, Hakan; Keskin, Ebru Yılmaz; Şenses, Dursun Ali; Erdem, Ayhan; Dikici, Bünyamin; Kocabay, KenanMalignant infantile osteopetrosis (MIOP) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, which results in generalized osteosclerosis. This leads to abnormal bone marrow cavity formation and to the clinical signs and symptoms of bone marrow failure and nerve compression. Symptoms related to early or late hypocalcemia may appear as the first presentation of MIOP in a newborn. We present a 14-day-old boy with neonatal hypocalcaemia due to MIOP.Öğe Supraventriküker taşikardi ile kendini gösteren üç aylık tuberoskleroz olgusu(2009) Uzun, Hakan; Yavuz, Taner; Şenses, Dursun Ali; Arslanoğlu, İlknur; Alagöz, Demet; Kocabay, KenanTuberoskleroz birçok organda hamartomlara neden olan otozomal dominant kalıtımla geçen bir bozukluktur. Çocukluk çağının en sık görülen kalp tümörü olan rabdomyomların tuberoskleroz ile olan ilişkisi iyi bilinmektedir. Kardiyak rabdomyomlara bağlı aritmiler tuberosklerozun başlangıç bulgusu olabilir. Biz burada, ekokardiyografi incelemesinde çok sayıda kardiyak rabdomyom bulunan, supraventriküler taşikardi ile kendini gösteren 3 aylık bir kız olgusunu sunuyoruz.Öğe Vitamin D-resistant rickets, primary hypothyroidism, and diabetes insipidus associated with infantile cystinosis(Karger, 2006) Şimşek, Enver; Şenses, Dursun Ali; Mindan, Gültekin; Kocabay, Kenan…Öğe Yenidoğanlarda pnömotoraks deneyimlerimiz(2006) Ağartan, Aldırmaz Canan; Uzun, Hakan; Mindan, Gültekin; Şenses, Dursun Ali; Kocabay, KenanAmaç: Yenidoğan döneminde solunum sıkıntısı yapan nedenlerden biri de pnömotoraks olup, mekanik ventilasyon tedavisi, mekonyum aspirasyonu sendromu, solunum güçlüğü sendromu ve perinatal asfiksi nedeniyle canlandırma işlemi uygulanan olgularda gelişme riski yüksektir. Hastanemiz yenidoğan bakım ünitesinde semptomatik pnömotoraks saptanarak tedavi edilen olgular geriye dönük olarak incelenmiştir. Gereç ve yöntem: Ocak 2003-Ocak 2006 tarihleri arasındaki 7 pnömotorakslı olguda gestasyonel yaş, ağırlık, aminon sıvısının mekonyumla boyalı olup olmadığı, primer akciğer patolojisi varlığı ve pnömotoraksın tarafı değerlendirildi. Tanıda akciğer grafisi ve bazı olgularda konjenital anomali varlığını araştırmak için bilgisayarlı tomografi yapıldı. Toraks drenaj işlemi için 10 F tüp kullanıldı. Bulgular: 7 olgunun değerlendirilmesinde; pnömotoraks insidansı %1,2 (7/570), erkek kız oranı 1,3, başvuru zamanı 10 saat ile 6 gün idi. 5 hasta (%71,4) prematürdü. Pnömotoraks sağda 3 (%42,9), bilateral 4 (%57,1) vakada mevcuttu. Serimizde mortalite % 57,1 olarak bulunmuştur. Vefat eden olguların büyük bir kısmı (%75) prematüre, solunum güçlüğü sendromlu ve iki taraflı pnömotoraksı olan olgulardı. Sonuç: Yenidoğan pnömotoraks olgularında mortalitenin prematürite, SGS ve iki taraflı pnömotoraks varlığında yüksek olması literatür ile uyumlu bulundu.
