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Öğe A Case of Bronchogenic Cyst Mimicking Foreign Body Aspiration(Lippincott Williams & Wilkins, 2013) Özkan, Aybars; Okur, Mesut; Kaya, Murat; Küçük, AdemBronchogenic cysts (BCs) can be life threatening if they compress vital structures in infants and small children. In particular, subcarinal cysts can be life-threatening and compromise the airways. In infants, the initial presentation may be respiratory distress. We report a case of mediastinal cystic mass compressing the main left bronchus. The case was an 18-month-old boy who had been admitted with acute respiratory distress. Chest x-ray showed overdistension of the left lung and a mediastinal shift. Foreign body aspiration was diagnosed. Magnetic resonance imaging was performed, which has shown a mediastinal cystic mass; therefore, the patient underwent thoracotomy. Surgical intervention revealed a subcarinal extrapulmonary BC that compresses the left main bronchus. The diagnosis of BC was confirmed with pathological investigation. In this report, we present a case of BC with the emphasis on the differential diagnosis with foreign body aspiration.Öğe A case of isolated thrombocytopenia due to cobalamin deficiency(Springer Japan Kk, 2011) Okur, Mesut; Özkan, Aybars; Güneş, Cemalettin; Kaya, Murat; Kocabay, KenanThe most common form of isolated thrombocytopenia is idiopathic thrombocytopenic purpura (ITP) in childhood. Hence, pediatricians consider a possible diagnosis of ITP in patients with isolated thrombocytopenia who are admitted to hospital with complaints of skin findings such as petechiae, purpura, and ecchymosis. It is well known that cobalamin deficiency may also cause thrombocytopenia together with anemia and leukopenia in children. However, isolated thrombocytopenia due to cobalamin deficiency has rarely been reported in literature. In this case report, we present a 7-year-old female patient with isolated thrombocytopenia that was improved by cyanocobalamin therapy.Öğe A child with deep face burn caused by chafing fuel(Kare Publishing, 2013) Özkan, Aybars; Katrancı, Ali Osman; Okur, Mesut; Kaya, Murat; Küçük, Adem[No abstract available]Öğe Çocuklarda yabancı cisim aspirasyonu: Anket tabanlı bir çalışma(Balıkesir Üniversitesi, 2021) Kiliçaslan, Önder; Türen, Betül; Özkan, Aybars; Ak, Gülden; Temizkan, Ramazan Cahit; Kocabay, KenanÖz Amaç: Yabancı cisim aspirasyonları (YCA); hava yollarının tıkanıklığı ile birlikte ortaya çıkan hayatı tehdit eden acil bir durumdur. Bu çalışma ile çocukların sürekli bakımlarını üstlenen annelerin çocukluk yaş grubunda ciddi sonuçlar doğurabilen YCA konusundaki bilgi düzeylerini ölçmeyi ve cevaplardan bağımsız olarak anneleri bilgilendirmeyi amaçladık. Gereç ve Yöntemler: Çalışmaya 6 ay ile 5 yaş arasında çocuğu olan 1034 anne dahil edildi. Katılımcılara sosyodemografik özellikleri, YCA ile ilgili bilgileri soruldu. Bulgular: Çoğunlukla anneler; 21-30 yaş arasında (%48.94), ilköğretim mezunu (%34.62), ev hanımı (%66.05) idi. Aileler genelde 2-3 çocuğa sahip idi. Annelerin çoğu (%65.73) hayatlarında hiç YCA olan çocuk görmemişlerdi. Eğitim düzeylerine bağlı tüm gruplarda, en sık YCA görünen yaş grubu için 1-3 yaş seçeneği, en fazla üniversite mezunu katılımcılar (%66.19) tarafından işaretlenmişti. Eğitim düzeyi arttıkça YCA’nın ölümcül olabileceği, koruyucu önlemlerin bütünlüğü, ilk müdahalenin önemi ve müdahalede doğru bilginin kaynağı konularında farkındalığın arttığı gözlendi. Katılımcıların çoğu (%72.74) YCA ile karşılaştıklarında acil servise başvuracaklarını belirtmişti. Sonuç: YCA’nın yol açacağı morbidite ve mortalitenin engellemesinde en önemli basamak önlenmesidir. Önlemenin de en kolay yolu toplumun bilinçlendirilmesi ve eğitilmesinden geçer.Öğe An easy technique for removal of knotted catheter in the bladder: percutaneous suprapubic cystoscopic intervention(E-Century Publishing Corp, 2013) Özkan, Aybars; Okur, Mesut; Kaya, Murat; Büyükkaya, Ramazan; Katrancı, Ali Osman; Küçük, AdemUncontaminated urine samples are indispensable to precisely diagnose urinary tract infections in newborns or infants. Among many clinical interventions for urine collection are described, the most common noninvasive practice is using sterile bags, associated with significant contamination of samples. In children, however, invasive methods i.e. catheterization, are generally needed for reliable urine specimens. Almost always all the inserted catheters are easily drawn back, nevertheless, might not work as expected, and lead to considerable problems that cannot be overcome. Herein, a case of a female newborn treated with a successful percutaneous suprapubic cystoscopic procedure for extracting knotted urinary catheter in the bladder is presented. The least invasive and easiest technic is suggested to be used when catheter is knotted in the bladder, as elaborately stated.Öğe Effect of combined anti-inflammatory and antioxidant therapy on ischemia-reperfusion injury in rat ovary: an experimental study(E-Century Publishing Corp, 2016) Kaya, Murat; Özkan, Aybars; Eröz, Recep; Soyer, Tutku; Kabaklıoğlu, Murat; Oktay, Murat; Küçük, AdemAn experiemental study was performed to evaluate the effect of combined anti-inflammatory and antioxidant theraphy on ischemia-reperfusion injury in rat ovary. Also the results of combined theraphy is aimed to compared with monotherapy. Fifty-four female Wistar rats were randomly divided into 9 equal groups (n=6). In Sham group right ovaries of the rats were sampled without generating ischemia and reperfusion injury via median laparatomy. Ischemia/Reperfusion (I/R) was performed by clamping the vascular supply of right ovary for 3 hours (I/R 1 group) and 6 hours (I/R 2 group), respectively. After one hour reperfusion, rats recieved 20 mg/kg Methylprednisolone (Pred 1; 3 hours ischemia and Pred 2; 6 hours ischemia) and 50 mg/kg Vitamin C (Vit C 1; 3 hours ischemia and Vit C 2; 6 hours ischemia). The combined therapy groups (Pred+Vit C 1 and Pred+Vit C 2) were adminstered same doses of both Methylprednisolone and Vitamin C. Rats were sacrifed after 24 hours of reperfusion and ovarian tissues were sampled for oxidative markers [malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] biochemically. Histopathological findings of inflammation (follicular cell degeneration, vascular congestion, hemorrhage and infiltration by inflammatory cells) were also evaluated with an injury score grading normal findings to severe injury (Grade 0 to 3). The results were compared among groups. Mean levels of antioxidant enzymes and histopathologic grades showed significant difference among groups (P<0.05). MDA and CAT levels were lower in Pred+Vit C 1 than Pred 1, Vit C 1 and I/R 1 (P<0.05). SOD and CAT levels were lower in Pred+Vit C 2 than Pred 2 and I/R 2. Total injury scores were lower in Pred+Vit C 1 and Pred+Vit C 2 than I/R 1 and I/R 2 (P<0.05). The combined treatment of anti-oxidant and anti-inflammatory theraphy reduces the biochemical and histopathologic findings of I/R injury in rat ovary. These results are significantly comparable with the effect of monotheraphy.Öğe The Effect of Maximum Voided Volume on Response to Desmopressin Therapy in Children with Enuresis(Medical Assoc Nippon Medical Sch, 2012) Okur, Mesut; Özen, Semiha Fatma; Kocabay, Kenan; Çam, Kamil; Özkan, Aybars; Uzun, HakanPurpose: This study was aimed to determine the effect of maximum voided volume (MVV) on the efficacy of desmopressin. which is commonly used to treat primary monosymptomatic nocturnal enuresis (PMNE) in children and adolescents. Materials and Methods: Bladder capacity was measured with different methods in 52 patients with PMNE, and the effect of bladder capacity on desmopressin therapy was investigated. Results: Patients with PMNE in whom MVV was 70% or less of estimated bladder capacity were found to be unresponsive to desmopressin therapy. Conclusion: The MVV can be measured before desmopressin therapy in patients with PMNE as a marker to predict treatment success. Our results suggest that desmopressin should not be used in patients with low MVV. (J Nippon Med Sch 2012; 79: 255-258)Öğe An Extremely Rare Cause of Bruising in Children: Autoerythrocyte Sensitization Syndrome(Galenos Yayincilik, 2012) Okur, Mesut; Turan, Hakan; Özkan, Aybars; Güneş, Cemalettin; Kocabay, Kenan…Öğe Huge Abdominal Pseudocyst Following Ventriculoperitoneal Shunt Mimicking Massive Ascites(Düzce Üniversitesi, 2013) Özkan, Aybars; Kaya, Murat; Okur, Mesut; Kocabay, Gönenç; Kocabay, KenanAbdominal cerebrospinal fluid (CSF) pseudocyst is an uncommon complication of ventriculoperitoneal shunts. During the initial surgery a ventriculo-peritoneal catheter was inserted forassociated hydrocephalus in the neonatal period. And then the once revision of the shunt wasapplied. After six years this operations, we present a case of a 6-year-old girl has hugeabdominal CSF pseudocyst. She presented with abdominal distension mimicking ascites for2 weeks. A CT scan of the abdomen revealed a large cystic mass in the abdomen withpseudocyst walls. An exploratory laparotomy was performed and the cyst was extirpated withrevision of the shunt. Histological examination revealed a pseudocyst with endothelial liningand cerebrospinal fluid inside. Sometimes, it becomes very difficult to identify the source ofthese cysts which mimics ascites and misdiagnosed as ascites. We report this uncommon casewith a brief review of the literatureÖğe I Wish, If There Was A Circumcision Pill(Düzce Üniversitesi, 2013) Okur, Mesut; Kaya, Murat; Küçük, Adem; Özkan, Aybars“I wish, if there was a circumcision pill…”This sentence is the wish of a child when his turn forcircumcision comes. Circumcision is a very old, starting with the history of religions, celestial,medical, cultural practice. Of course, yesterday, today, tomorrow will be the most commonlyperformed surgical procedure. I understand that especially in Germany, the prohibition ofcircumcision, again renewed interest in and curiosity about the circumcision. This prohibitionnot only of members of the Muslim and Jewish religious will be at the same time led to effectson circumcision for medical reasons. In our country where a lot of circumcision is performed,a senior research to explain the benefits of circumcision to the whole world, if we had a goodreference work that may be it would not think to ban circumcision. To do this, first and foremostpractitioners of circumcision, universities, health ministry officials and their families haveresponsibility for role. With this review aimed that to expose the complications of circumcisionand following the procedure and to raise awareness in the community about circumcisionÖğe The importance of surgical timing in inguinoscrotal surgical pathologies [İnguinoskrotal cerrahi patolojilerde cerrahi zamanlamanın önemi](Duzce University Medical School, 2019) Kaya, Murat; Özkan, Aybars; Kabaklıoğlu, MuratAim: Various inguinal pathologies can occurred if the processus vaginalis cannot closed fully. The aim of this study was to evaluate all patients who underwent inguinoscrotal surgery operations between 2011 and 2018 in our clinic, in terms of age, gender and accompanying with another operation, retrospectively. Material and Methods: In this study, records of 807 patients who were performed inguinal surgery operations including 558 inguinal hernia repair, 184 orchiopexy and 65 hydroselectomy between 2011 and 2018 at Duzce University, Faculty of Medicine, Pediatric Surgery Department were evaluated retrospectively. Results: Mean age of the 558 patients who underwent inguinal hernia operation was 3.0±3.6 years, and 288 (51.6%) patients were older than 2 years of age. Of the patients who performed inguinal hernia operation, 411 (73.7%) were male and 147 (26.3%) were female. There was a statistically significant difference in terms of inguinal hernia repair side according to gender (p=0.038), and left inguinal hernia repair rate in females was detected higher than in males. Mean age of the 184 patients who performed orchiopexy operation was 4.0±3.4 years old, and only 46 patients (25.0%) who underwent orchiopexy were younger than 2 years of age. Mean age of the 65 patients who performed hydrocele operation was 4.6±4.1 years old. Conclusion: According to the results of this study, it is seen that the community does not have enough information about the right operation time of inguinal hernia and undescended testis, and that the society should be informed about this issue. © 2019, Duzce University Medical School. All rights reserved.Öğe Investigation of Vitamin D Deficiency inPre-School Children During Summer Season(2021) Temel, Esra Ulgen; Kocabay, Kenan; Özkan, AybarsAim:Vitamin D deficiency is an important public health problem, especially affecting children. Theaim of our study is to evaluate the serum 25 (OH) vitamin D levels of children during the summer and to determine some features such as exposure to the sun, oral vitamin D supplementation, and to examine the parameters that affect serum vitamin D levels.Methods:In our study, children aged between 12 and 83 months were included. A questionnaire was answered by families. In this cross-sectional study, serum 25 (OH) vitamin D levels of children and biochemical parameters were examined.Results:The mean serum 25 (OH) vitamin D level was 27.0±12.4 ng/ml. Vitamin D deficiency was found 17%, and vitamin D insufficiency was 6%. The children that taking daycare indoors and body mass index <5th percentile had lower serum 25 (OH) vitamin D levels. Children between the ages of 12-36 months and children with chronic diseases were found to have a shorter time to benefit from sunlight.Conclusion: The rate of vitamin D deficiency and insufficiency (<20 ng/ml) in children were found at 23% in summer season. Families and caregivers should be informed about vitamin D and should be aware of safe sun exposure.Öğe Jel yakıtına bağlı derin yüz yanığı gelişen bir çocuk olgu(2013) Özkan, Aybars; Katrancı, Ali Osman; Okur, Mesut; Kaya, Murat; Küçük, Adem…Öğe Late Presenting Bochdalek Hernia With Gastric Perforation(Lippincott Williams & Wilkins, 2015) Özkan, Aybars; Çil, Asudan Tuğçe Bozkurter; Kaya, Murat; Etçioğlu, Inci; Okur, MesutLate-onset congenital diaphragmatic hernias that give symptoms beyond the neonatal period are rare and are difficult to diagnose. The diagnosis is usually made in case of complications such as intestinal obstruction, strangulation, and perforation, which further necessitate immediate surgical repair. The case of a 5-year-old child presenting with acute respiratory distress with gastric strangulation and perforation secondary to Bochdalek hernia is reported here. Although presentation in the latter ages is less common, congenital diaphragmatic hernia should be included in the differential diagnosis of respiratory distress in children. Symptoms and diagnostic tools should truly be interpreted. Gastrointestinal complications must urgently be recognized, and early surgical intervention must be performed.Öğe Let us save the brain with cerebral oximeter: Two case reports(Wolters Kluwer Medknow Publications, 2017) Şeker, İlknur Suidiye; Özlü, Onur; Özkan, Aybars; Uzun, Hakan; Esbah, Ali Ümit; Çetin, PelinIn the neonates, tracheal atresia and tracheoesophageal fistula (TEF) surgery may result in hemodynamic instabilization, leading to cerebral perfusion insufficiency due to the retraction of the pulmonary vessels and truncus brachiocephalicus. We represented one male and one female neonates which were performed thoracoscopic primary repair of TEF through right thoracotomy at the 3th and 4th postpartum day. Anesthesia was induced using sodium thiopental (5 mg/kg), fentanyl 4 mcg, and rocuronium (0.5 mg/kg) given through intravenous route. Sevoflurane 2% and 50% O2in air were used for the maintenance therapy. During the right lung compression to expose posterior esophagus, no value was observed on the pulse oximeter (PO) probe placed on the right hand, and radial artery was not palpated. At the same time, oxygen saturation was observed as 96%-97% on the left foot probe. As the right cerebral oximeter values (rSO2) were rapidly decreased to 31%, the lung compression was ceased. Right pulse oximeter and right rSO2measurements return to the baseline levels. For the second case - different from the first case -both left and right rSO2was rapidly decreased to 40% levels and return to the baseline levels after was removed the retractors. Right PO and right and left cerebral rSO2values returned to baseline immediately when the retractor compression was ended During the operations involving the great vessels in neonates, cerebral perfusion could be preserved using cerebral oximeter. Cerebral oximeter is more efficient than pulse oximeter for detecting cerebral tissue oxygenation and could be helpful to minimize neuronal damage in the neonates. © 2019 African Journal of Paediatric Surgery | Published by Wolters Kluwer - Medknow.Öğe A Low Cost and Non-Complicated Circumcision; When, How, Where, Who Should Be Made by?(2019) Kaya, Murat; Özkan, Aybars; Kabaklıoğlu, MuratObjective: Circumcision, in Turkey as a Muslim country is one of the most commonly performed operation. The aim of this study is to retrospectively evaluated circumcision datas and discuss about 'a low cost and non-complicated circumcision; when, how, where, who should be made by'. Methods: 4059 patients who were circumcised between 2011-2018 were included in the study. The age of the patient, time of operation, presence of accompanying surgical pathology (inguinal hernia, undescended testis, hydrocele, etc.) and anesthesia type (local only, sedoanalgesia and general) were evaluated. Results: The mean age of 4059 patients was 4.1 years (± 3.29). The number of patients who had circumcised <2year was 1315 (32.40%), aged 2-6 who no recommended by child psychiatrists was 1154 (28.43%) and >6 year was 1590 (39.17%). 422 (10.40%) of patients who underwent circumcision had additional surgical pathology. The most common additional surgical pathologies were inguinal hernia (n=212, 50.24%), undescended testes (n=100, 23.70%) and hydrocele (n=32, 7.58%). Conclusions: Since the circulation of complicated surgical operations is intense, especially in the 3rd level public university hospitals are more appropriate to perform circumcision in patients who require additional operation to reduce the cost and hospitalization. If additional operation is not required, circumcision should be performed by private health institutions or certified 1st level family physicians. In terms of childhood psychology, it is important to take measures to increase the level of knowledge of families at this issue, since a significant number of families still circumcised their children aged 2-6 years.Öğe Malrotation-associated cholecystoduodenal fistula(2014) Özkan, Aybars; Özaydın, İsmet; Kaya, Murat; Küçük, Adem; Katrancı, Ali OsmanBackground: Cholecystoduodenal fistula (CDF) is the most common cholecystenteric fistula. It is a late complication of gallbladder disease with calculus and is mainly encountered in the elderly and females. Case Report: We report the case of a teenage patient with cholecystoduodenal fistula and malrotation. Direct plain abdominal x-ray demonstrated air in the biliary system. Computed tomography revealed CDF-associated with an anomaly of intestinal malrotation. She had gallstones (with a few stones in the gallbladder) and cholecystitis. CDF is caused by malrotation, and cholecystitis has not been reported before. In this regard our patient is the first and youngest reported case. Conclusions: We suggest that CDF is probably a consequence of malrotation. The patient's clinical features and operative management are presented and discussed with current literature. © Am J Case Rep, 2014.Öğe Paradoxal aspects in circumcision(2013) Özkan, Aybars; Kaya, Murat; Okur, Murat; Türker, Y.[No abstract available]Öğe Phosalone Toxicity on Liver and Pancreas: Role of Vitamins E and C(Asian Journal Of Chemistry, 2013) Demirin, Hilmi; Gökalp, Osman; Kaya, Ertuğrul; Büyükvanlı, Bora; Cesur, Gökhan; Özkan, Aybars; Kaya, MuratPhosalone (6-chloro-3-[diethoxyphosphinothioylsulfanylmethyl]-1,3-benzoxazol-2-one) is one of the most commonly used organophosphorus pesticides in the peat control of crops. Subchronic phosalone exposure was evaluated for its effects on the serum activities of some enzymes concerning hepatic and pancreatic damage including aspartate aminotransferase (AST), alanine aminotransferase (ALT), glutamyltransferase (GGT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), cholinesterase (ChE); and finally protective effects of combination of vitamins E and C in 24 wistar-albino rats. Experimental groups were as follows: control group (n = 8); a group treated with 120 mg/kg body weight phosalone (P group, n = 8); and a group treated with 120 mg/kg body weight phosalone + vitamin E + vitamin C (P+V group, n = 8). The P and P+V groups were treated orally with phosalone on 5 days a week for 4 weeks. The serum activities of the above mentioned enzymes were analyzed. In the samples phosalone significantly increased the activities of ALT, LDH and decreased ChE (p < 0.05). However no significant change was detected for the remainder enzymes (p > 0.05). In the P+V group, ALT and LDH activities were significantly increased and ChE decreased (p < 0.05). It is concluded that subchronic phosalone causes rat liver damage to an extent, which is somewhat reflected on the liver enzymes. Furthermore, a combination of vitamins E and C can reduce the toxic effects of phosalone on liver tissue of rats.Öğe Protective effects of ursodeoxycholic acid in experimental corrosive esophagitis injury in rats(Edizioni Luigi Pozzi, 2017) Küçük, Adem; Topaloğlu, Naci; Yıldırım, Şule; Tekin, Mustafa; Erbaş, Mesut; Kiraz, Hasan Ali; Özkan, AybarsAccidental caustic ingestions are serious medical problems especially in childhood. Various treatment modalities are being used for the complications of caustic injuries such as stricture formation. The aim of this study is to establish whether ursodeoxycholic acid (UDCA) has protective effects on experimental corrosive esophagitis in rats. Twenty four Wistar-albino rats, weighing 220-240 g, were used in the study. Experimental animals were divided in three groups randomly: UDCA treatment group (Group 7; n:8), control group (Group K n: 8) and sham group (Group S, n: 8). In group T and S corrosive esophagitis was induced. UDCA (5 mg/kg) was performed to the group T for 10 days orally. All animals were sacrificed at the end of procedures and histopathological changes in esophageal tissue were scored by a single investigator who was blind to the groups. In group T inflammation was present in two rats, muscularis mucosa injury in two rats, grade I collagen deposition in six rats and grade 2 in two rats. In comparison with group S these were statistically significant (p value was 0.003, 0.003 and 0.015, respectively). UDCA has protective effect in experimental corrosive esophagitis.
