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Öğe Effect of Different Anesthetic Agents Management on Electrocardiographic Changes of Patients Operated under Regional Intravenous Anesthesia(Oğuz KARABAY, 2020) Yorulmaz, İlknur Suidiye; Akman Köse, Gökçe; Demiraran, Yavuz; Cangür, ŞengülObjective: We compared cardiac effects, electrocardiographic changes by intravenous regional anesthesia (IVRA) with lidocaine and lidocaine + ketamine.Materials and Methods: Prospective, randomised, double blind study was performed in the operating room of Düzce University Hospital. Seventy patients between 18-60 years, ASA I-II and who were undergo IVRA for arm and forearm operations. Patients were divided into two groups randomly. Group 1: 0.5% Lidocaine+Ketamine 0.8 mg/kg; 40 ml. Group 2: 0.5% Lidocaine 40 ml. 20 minutes after injection the distal cuff was inflated, and the proximal cuff deflated with a rate of 50 mmHg in every 3 minutes. Time periods of the recordings were 0, 5, 10, 15, 30, 45, 60th minutes after the beginning of deflation and 10 minutes after the deflation. Non-invasive blood pressure values, heart rate, pulse oximetry values were recorded. Electrocardiographic changes on PR, RR intervals, QT, QTc were recorded.Results: QT basal value measured in Group Lidocaine+Ketamine is significantly lower than QT5th min, QT10th min, QT15th min, QT30th min, QT45th min, QT60th min and QTtur10. QTcbasal values measured in Group Lidocaine+Ketamine were significantly lower than QTc tur10 values (p <0.001). Conclusions: In Group Lidocaine, no significant differences was observed. After the deflation of tourniquet was completed, QT and QTc values and noninvasive blood pressures were significantly higher in Group Lidocaine+Ketamine.Öğe The effect of hypoxic and normoxic cerebral oximetry levels and oxidative stress on cognitive functions after carotid endarterectomy(Lippincott Williams & Wilkins, 2021) Yorulmaz, İlknur Suidiye; Karaca, Okay Guven; Alpay, Merve; Bal, Melih[Bastract Not Available]Öğe Effect of PEEP, Zero PEEP and Intraabdominal Pressure Levels on Cerebral Oxygenation in the Morbidly Obese Undergoing Sleeve Gastrectomy(Mary Ann Liebert, Inc, 2017) Yorulmaz, İlknur Suidiye; Demiraran, Yavuz; Salihoğlu, Ziya; Umutoğlu, Tarık; Özaydın, İsmet; Doğan, SamiThe study is designed to determine the effect of zero end expiratory pressure (ZEEP) and 5mmHg positive end expiratory pressure (5PEEP) on cerebral oxymeter (CO) levels in morbidly obese (MO) patients. Study was performed on 60 morbidly obese patients between 18-60 years old, American Society of Anesthesiology 2-3 status, scheduled to undergo laparoscopic sleeve gastrectomy under general anesthesia. The patients were divided into two groups: those ventilated with no PEEP (group ZEEP, n = 30) and those ventilated with 5 cmH(2)O PEEP levels (group 5PEEP, n = 28). rSO(2) values were measured. Data were recorded as basal, after the induction (A ind) of anesthesia, 5 min before insufflation (BI), 5 min after insufflation (AI), 15, 30, 45, and 60 min after induction, 5 min before desufflation, and 5 min after desufflation (AD). Invasive arterial pressures, CO values, peripheral oxygen saturation, end tidal carbondioxide, and intraabdominal pressure (IAP) were recorded in these time periods in all groups. Arterial blood samples were analyzed in terms of the 5BI, 5AI, and 5AD periods. There was a negative correlation between IAP and left CO on pneumoperitoneum time in group 5PEEP. Correlation was observed between bilateral CO values and ideal body weight (IBW), lean body weight (LBW), body surface area BSA, in group ZEEP. Correlation was observed between IBW, LBW, and right CO values in group 5PEEP. PEEP application may have a protective effect on cerebral oxygenation.Öğe The effect of piracetam and hyperbaric oxygen application on return of nerve damage in rats with a model of sciatic nerve damage(Lippincott Williams & Wilkins, 2021) Yorulmaz, İlknur Suidiye; Canoğlu, Umut Caner; Gamsızkan, Mehmet; Iskender, Abdulkadir; Alpay, Merve; Sungur, Mehmet Ali[Bastract Not Available]Öğe Tramadol and levobupivacaine wound infiltration at Cesarean delivery for postoperative analgesia(Springer Japan Kk, 2013) Demiraran, Yavuz; Albayrak, Mustafa; Yorulmaz, İlknur Suidiye; Özdemir, İsmailThe aim of the present study was to investigate whether levobupivacaine and tramadol wound infiltration decreases postoperative pain following Cesarean section and reduces the need for analgesics in the immediate post-delivery period. Ninety patients (aged 18-40 years) scheduled for elective Cesarean section under general anesthesia were randomly allocated to one of the three groups: the placebo group (group P) received 20 mL local wound infiltration with 0.9 % saline solution; the levobupivacaine group (group L) received 20 mL local wound infiltration with levobupivacaine 0.25 %; and the tramadol group (group T) received 20 mL local wound infiltration with 1.5 mg/kg tramadol within 0.9 % saline solution. Following the closure of the uterine incision and the rectus fascia, 20 mL solution was infiltrated subcutaneously along the skin wound edges. The primary outcome was 24-h tramadol consumption. Secondary outcomes were recorded VAS scores, diclofenac requirement, fever, vomiting, and wound infection. At 15 min postoperatively, VAS values were lower in groups T and L than group P (P = 0.0001). The mean 24-h tramadol consumption was lowest in group T (P = 0.0001) and it was lower in the group L compared to group P (P = 0.007) (401.6, 483.3, and 557.5 mg for T, L, and P groups, respectively). There was no difference among groups regarding the need for supplemental analgesia (rescue diclofenac doses) (P > 0.05). We conclude that wound infiltration with tramadol and levobupivacaine in patients having Cesarean section under general anesthesia may be a good choice for postoperative analgesia.Öğe An unexpected challenging airway: Urticaria factitia caused difficult mask ventilation and tracheal intubation(Elsevier Science Inc, 2019) Özlü, Onur; Yorulmaz, İlknur Suidiye; Esbah, Ali Ümit; Er, Uygur…Öğe Yenidoğanlarda farklı anestezik yöntemlerin serum bilirubin düzeyi üzerindeki etki ve sonuçları(Düzce Üniversitesi, 2009) Yorulmaz, İlknur Suidiye; Demiraran, YavuzGiriş: Bu çalışmada, amacımız farklı anestetik yöntemlerin yenidoğan sarılığı üzerine olan etkilerinin araştırılmasıdır.Metod: Fakültemiz etik kurul onayından sonra ASA1-2 statüsünde elektif sezeryan operasyonu planlanan 100 gebe çalışmaya alındı. Hastalar 5 eşit gruba ayrılarak anestetik yöntemler (genel anestezi, spinal anestezi, total intravenöz anestezi, epidural anestezi, normal spontan vajinal doğum) uygulandı. Grup GA'ya indüksiyonda 2 mg/kg propofol,1 mg/kg lystenon, idamede %1-2 MAC sevoflurane ve 0,1µg/kg/dk remifentanil verildi. Grup SA'ya intratekal hiperbarik bupivacaine verildi. Grup TİVA'ya indüksiyonda 2 mg/kg/saat dozunda propofol, 1mg/kg lystenon, idamede 10-8-6-4 mg/ kg/h propofol, 0,1µ /kg/dk remifentanil uygulandı. Postoperatif analjezi için Grup EA'ya epidural, diğer gruplara ise iv yoldan tramadol verildi. Umblikal kord klampe edildikten sonra umblikal kord kan gazı alındı. Postoperatif 1. ve 5. dakikadaki APGAR skorları ile 24. saat ve 5. gündeki yenidoğan serum bilirubin seviyelerine bakıldı.Sonuçlar: 24.saat ve 5. gün yenidoğan bilirubin değerleri açısından incelendiğinde gruplar arasındaki değerlendirmelerde istatistiksel olarak anlamlı fark olmadığı, ama grupların ikili değerlendirilmeleri sonucunda grup TİVA ve grup EA ve grup GA `da 24.saat direk bilirubin değerlerin de istatistiksel olarak anlamlı fark olduğu görüldü (p=0.021). Fototerapi ihtiyacı açısından değerlendirildiğinde grupların kendi aralarında istatistiksel olarak anlamlı fark saptanmamasına rağmen, yüzde olarak bakıldığında en yüksek oranın %25 ile grup TİVA' da olduğu görüldü. Grup GA ve grup EA' da %15 ile ikinci sırada, grup SA' da ise %10 ile 3. sırada, grup NSVD grubunda ise %5 ile en düşük düzeyde olduğu gözlendi. ( Şekil 2) Bupivakain, remifentanil, glikozillenmiş bupivakain, tramadol miktarları ve bilirubin seviyeleri arasında ilaç dozu- bilirubin seviyesi olarak istatistiksel açıdan fark saptanmadı.Tartışma: Vaka sayılarının arttırılmasıyla daha net sonuçların ortaya çıkacağını düşünmekteyiz
