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Öğe Bilateral Pathological Intracerebral Calcifications: Neurological and Psychiatric Evaluation(Düzce Üniversitesi, 2008) Gül, H Levent; Koçer, Emel; Çağrıcı, Sultan; Tutkan, Hava; Börü, Ülkü TürkBilateral, symmetric, calcium and other mineral deposits occur in basal ganglia, thalamus, cerebellum, and white matter off cerebral hemisphere are rare disorders. Hypoparathyroidism and Fahr’s disease (progressive idiopathic strio-pallidodentat calsinozis) are the most common two pathologies in etiology of bilateral calcifications. Extrapyramidal problems are the most commonly seen clinical finding in these patients. In this article in which neurological and psychiatric disorders in relation to calcifications were discussed, seizures and headache problems were more prominent in our patientsÖğe Higher P-wave dispersion in migraine patients with a higher number of attacks(Wiley-Blackwell, 2010) Koçer, Abdulkadir; Eryılmaz, Mehmet; Tutkan, Hava; Ercan, Nurten; Küçükbayrak, Zeynep Seçkin…Öğe Higher P-Wave Dispersion in Migraine Patients with Higher Number of Attacks(Hindawi Publishing Corporation, 2012) Koçer, Abdulkadir; Eryılmaz, Mehmet; Tutkan, Hava; Ercan, Nurten; Küçükbayrak, Zeynep SeçkinObjective and Aim. An imbalance of the sympathetic system may explain many of the clinical manifestations of the migraine. We aimed to evaluate P-waves as a reveal of sympathetic system function in migraine patients and healthy controls. Materials and Methods. Thirty-five episodic type of migraine patients (complained of migraine during 5 years or more, BMI < 30 kg/m(2)) and 30 controls were included in our study. We measured P-wave durations (minimum, maximum, and dispersion) from 12-lead ECG recording during pain-free periods. ECGs were transferred to a personal computer via a scanner and then used for magnification of x400 by Adobe Photoshop software. Results. P-wave durations were found to be similar between migraine patients and controls. Although P WD (P-wave dispersion) was similar, the mean value was higher in migraine subjects. P WD was positively correlated with P max (P < 0.01). Attacks number per month and male gender were the factors related to the P WD (P < 0.01). Conclusions. Many previous studies suggested that increased sympathetic activity may cause an increase in P WD. We found that P WD of migraine patients was higher than controls, and P WD was related to attacks number per month and male gender. Further studies are needed to explain the chronic effects of migraine.Öğe İnme hastalarında lezyon lokalizasyonu ve depresyon ilişkisi(2008) Koçer, Emel; Bilge, Cevdet; Çağrıcı, Sultan; Tutkan, Hava; Koçer, AbdulkadirAmaç: Bu çalışmanın amacı inme hastalarında lezyon lokalizasyonu ile depresyon arasındaki ilişkiyi araştırmaktır. Yöntem: Daha önce hiç inme öyküsü olmayan ve çalışmaya alınma kriterlerini karşılayan 40 hasta 6 ay süreyle prospektif olarak değerlendirildi. Depresyon varlığı bir uzman psikiyatrist tarafından DSM-IV tanı kriterleri ve Hamilton depresyon skalası kullanılarak değerlendirildi. Kraniyal görüntülemelerle elde edilen lezyon lokalizasyonuna ait veriler standart bir metodoloji kullanılarak ön, orta veya arka / sağ veya sol hemisfer yerleşimli lezyonlar şeklinde sınıflandırıldı. Takip sürecinde depresyon gelişen olgular ile depresyon gelişmeyen olgular arasındaki lezyon farklılıkları araştırıldı. Bulgular: Çalışma grubumuz 13’ü kadın (%32.5) ve 27’si erkek (%67.5) 40 hastadan oluşmaktaydı. Depresyon ile hemisfer farklılığı arasında farklılık saptanmamasına karşın, ön taraf tutulumu ile depresyon arasında istatistiksel olarak anlamlı fark olduğu tespit edildi. Sonuç: Daha önce birçok yapısal görüntüleme çalışmalarının aktardığı, nöropsikolojik değerlendirmeler ve fonksiyonel çalışmalar depresyon ile sol taraf ve ön bölge lezyonları arasında bir ilişkiyi gösteren verilere benzer olarak bu çalışmada da depresyon ile ön bölge tutulumu arasında bir ilişki bulunabileceği saptanmıştırÖğe Patolojik iki taraflı intraserebral kalsifikasyonlar: Nörolojik ve psikiyatrik değerlendirme(2008) Gül, H. Levent; Koçer, Emel; Çağrıcı, Sultan; Tutkan, Hava; Börü, Türk ÜlküBazal gangliyonlar, serebral hemisfer beyaz cevherinde ve serebellumun dentat nükleuslarında bilateral kalsifikasyonlar veya diğer minerallerin depolanması nadir bir hastalıktır. Hipoparatiroidizm ve idyopatik strio-pallido-dentat kalsinoz (Fahr hastalığı) patolojik intraserebral kalsifikasyonların en sık rastlanan iki sebebidir. Bu hastalarda hareket bozuklukları en sık rastlanan bulgudur. Kalsifikasyonlara eşlik eden nörolojik ve psikiyatrik bozukluklar tartışıldığı bu makalede, literatürden farklı olarak nöbetlerin ve başağrısı problemlerinin bizim hastalarımızda baskın olması dikkat çekiciydi.Öğe The relationship between depression and lesion localization in first-ever stroke patients(2008) Koçer, Emel; Bilge, Cevdet; Çağrıcı, Sultan; Tutkan, Hava; Koçer, AbdulkadirObjective: There is a need for more systematical and wide-spread studies because of the methodological problems in scientific studies discussing the relationship between depression and localization. Method: Forty patients with first stroke and meeting the inclusion criteria were examined prospectively during 6 month study period. The diagnosis of depression was made by using DSM-IV diagnostic tool and the patients were followed by using Hamilton Depression Scale by a specialist on psychiatry. The findings got from the cranial imaging were evaluated and classified as lesions located in anterior, posterior or medial part / in the left or right hemisphere by using a standard method. The differences of lesions between the patients who developed the depression and the patients without depression were evaluated during follow-up period. Results: The study population consisted of 40 patients - 13 women (32.5%) and 27 men (67.5%). The relationship between depression and lesion localization whether right or left hemisphere was not significant , but the relationship between depression and anteriorly located lesions was statistically significant. Conclusion: Additional to previous structural imaging studies, neuropsychological examinations and functional studies reporting a relation between development of depression and lesions located on the left side and anterior part, our results show that there could be a relationship between depression and anterior lesions in the first ever stroke patients.Öğe The relationship between depression and lesion localization in first-time stroke patients(Kure Iletisim Grubu A S, 2008) Koçer, Emel; Bilge, Cevdet; Cagrici, Sultan; Tutkan, Hava; Koçer, AbdulkadirObjective: There is a need for more systematical and wide-spread studies because of the methodological problems in scientific studies discussing the relationship between depression and localization. Method: Forty patients with first-time stroke were examined prospectively during 6 month study period. The diagnosis of depression was made by using SCID P interviews and the patients were followed by using Hamilton Rating Scale for Depression Scale by a psychiatrist The findings from the brain imaging were evaluated and classified as lesions located in anterior, posterior or medial part of either left or right hemisphere by using a standard method. The differences of lesions between the patients who developed the depression and the patients without depression were evaluated during follow-up period. Results: The study population consisted of 40 patients; 13 women (32.5%) and 27 men (67.5%). The relationship between depression and lesion localization whether right or left hemisphere was not significant, but the relationship between depression and anteriorly located lesions was statistically significant. Conclusion: Although previous structural imaging studies, neuropsychological examinations, and functional studies reported a relationship between development of depression and locations of lesions usually on the left anterior part of the brain, our results showed a significant relationship between depression and anterior lesions in the first-time stroke patients.
