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    The frequency of osteoporosis in hemodialysis and continuous ambulatory peritoneal dialysis patients according to PTH levels after active vitamin D therapy during the two years period
    (2010) Kadiroğlu, Ali Kemal; Turgutalp, Kenan; Yılmaz, Zahid Selim; Şit, Dede; Kara, İsmail Hamdi; Kayabaşı, Hasan; Yılmaz, Mehmet Emin
    Aim: Osteoporosis is a skeletal disorder that is characterized by low bone mass, micro-structural degeneration of bone and high risk of fracture. In this study our aim was to detect the frequency of osteoporosis in hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) patients according to Parathyroid Hormone (PTH) after vitamin D therapy during the two years period. Materials and method: 18 HD patients (12 male, 6 female) and 12 CAPD patients (8 male, 4 female) undergoing to dialysis therapy in dialysis center of Medicine Faculty Hospital in Dicle University were enrolled to the study. The patients were evaluated with bone mineral density which was measured by left heel quantitative ultrasound before and after the active vitamin D therapy. The blood samples were collected for biochemical analysis in the morning after 12 hours fasting period before and after the active vitamin D therapy. Results: After the therapy T and Z scores bone mineral density and ALP values were increased in the group that PTH values were between 120-250 pg/ml and more than 250 pg/ml. But these parameters were decreased in the group that PTH were lower than 120 pg/ml. Osteoporosis percentage were 23 % in PTH value <120 pg/ml, %20 in PTH value between 120-250 pg/ml and 20 % in PTH >250 pg/ml in the initial measurement. After the therapy these were 30 %, 0 % and 20 % relatively. Conclusion: Before the treatment there was not a statistical difference between T score of 3 groups. After the treatment there was a statistically significant difference. Especially T score was better after the therapy in the second group that PTH values were between 120-250 pg/ml. © 2010 Düzce Medical Journal.
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    THE LONGITUDINAL EVOLUTION OF COVID-19 OUTCOMES AMONG HEMODIALYSIS PATIENTS: A NATIONWIDE MULTICENTRE CONTROLLED STUDY
    (Oxford Univ Press, 2022) Öztürk, Savaş; Turgutalp, Kenan; Arıcı, Mustafa; Görgülü, Numan; Tonbul, Halil Zeki; Eren, Necmi; Gençer, Vedat
    [Bastract Not Available]
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    The Longitudinal Evolution of Post-COVID-19 Outcomes Among Hemodialysis Patients in Turkey
    (Elsevier Science Inc, 2022) Öztürk, Savaş; Turgutalp, Kenan; Arıcı, Mustafa; Görgülü, Numan; Tonbul, Halil Zeki; Eren, Necmi; Gençer, Vedat
    Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A control HD group without COVID-19 was selected from patients in the same center. We investigated the characteristics and outcomes in the follow-up of HD patients and compare them with the non-COVID-19 group.Results: A total of 1223 patients (635 patients in COVID-19 group, 588 patients in non-COVID-19 group) from 47 centers were included in the study. The patients' baseline and HD characteristics were almost similar. The 28th-day mortality and mortality between 28th day and 90th day were higher in the COVID-19 group than non-COVID-19 group (19 [3.0%] patients vs. none [0%]; 15 [2.4%] patients vs. 4 [0.7%] patients, respectively). The presence of respiratory symptoms, rehospitalization, need for home oxygen therapy, lower respiratory tract infection, and arteriovenous (AV) fistula thrombosis was significantly higher in the COVID-19 group in both the first 28 days and between 28 and 90 days. In the multivariable analysis, age (odds ratio [OR] [95% CI]: 1.029 [1.004-1.056]), group (COVID-19 group vs. non-COVID-19 group) (OR [95% CI]: 7.258 [2.538-20.751]), and vascular access type (tunneled catheter/AV fistula) (OR [95% CI]: 2.512 [1.249-5.051]) were found as independent parameters related to 90-day mortality.Conclusion: In the post-COVID-19 period, maintenance HD patients who have had COVID-19 have increased rehospitalization, respiratory problems, vascular access problems, and high mortality compared with the non-COVID-19 HD patients.
  • Küçük Resim
    Öğe
    The Frequency of Osteoporosis in Hemodialysis and Continuous Ambulatory Peritoneal Dialysis Patients According to PTH Levels after Active Vitamin D Therapy during the Two Years Period
    (Düzce Üniversitesi, 2010) Kadiroglu, Ali Kemal; Turgutalp, Kenan; Yılmaz, Zulfikar; Şıt, Dede; Kara, İsmail Hamdi; Kayabaşı, Hasan; Yılmaz, Mehmet Emin
    Aim: Osteoporosis is a skeletal disorder that is characterized by low bone mass, micro-structuraldegeneration of bone and high risk of fracture. In this study our aim was to detect the frequencyof osteoporosis in hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD)patients according to Parathyroid Hormone (PTH) after vitamin D therapy during the two yearsperiod.Materials and method: 18 HD patients (12 male, 6 female) and 12 CAPD patients (8 male, 4female) undergoing to dialysis therapy in dialysis center of Medicine Faculty Hospital in DicleUniversity were enrolled to the study. The patients were evaluated with bone mineral densitywhich was measured by left heel quantitative ultrasound before and after the active vitamin Dtherapy. The blood samples were collected for biochemical analysis in the morning after 12hours fasting period before and after the active vitamin D therapy. Results: After the therapy T and Z scores bone mineral density and ALP values were increasedin the group that PTH values were between 120-250 pg/ml and more than 250 pg/ml. But theseparameters were decreased in the group that PTH were lower than 120 pg/ml. Osteoporosispercentage were 23 % in PTH value 250 pg/ml in the initial measurement. After the therapy these were 30 %, 0% and 20 % relatively.Conclusion: Before the treatment there was not a statistical difference between T score of 3groups. After the treatment there was a statistically significant difference. Especially T scorewas better after the therapy in the second group that PTH values were between 120-250 pg/ml