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Öğe Muscle Thickness in Lower Extremity and LocomotorFunctions in Children With Down Syndrome and TypicalDeveloping Peers(Wiley, 2026) Kınacı-Biber, Esra; Soylu, A. R.; Topuz, S.; Mutlu, A.Objectives Children with Down syndrome (DS) have deficits in motor skills that lead to stereotypical changes in the characteristics and adaptations of their movement. The aim of the study was to investigate locomotor characteristics and muscle thickness of the selected muscles in the lower extremity and the relationship between muscle thickness and locomotor parameters in children with DS and typically developing peers. Methods Children with DS (n?=?18; age: 5.36?±?0.60) and typically developing (TD) (n?=?30; age: 5.62?±?0.60) aged 4–7?years participated. Lower limb muscle thickness was assessed through B-mode ultrasound. The GAITRite system evaluated gait and running spatiotemporal parameters, using linear regression to determine the strength of the relationship between muscle thickness and these parameters. Results Compared to the TD group, the DS group had significantly less lower limb muscle thickness and differed significantly in gait and running parameters (p?
