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    In Vitro Antimicrobial Susceptibility Pattern Among Stenotrophomonas Maltophilia Strains Isolated From Clinical Specimens
    (Düzce Üniversitesi, 2014) Dal, Tuba; Tekin, Recep; Deveci, Özcan; Demirkaya, Safinaz; Mete, Mahmut; Dayan, Saim; Tekin, Alicem
    Aim: In this study, the determination of in vitro antimicrobial susceptibility rates amongStenotrophomonas maltophilia strains isolated from clinical specimens was aimed.Method: A total of 60 S. maltophilia strains isolated from various clinical specimens sent toDicle University Hospital clinical microbiology laboratory between January 2006 and September2011 were included retrospectively in this study. Urine samples were inoculated onto 5% sheepblood agar and Eosin-Methylene Blue (EMB) agar media, quantitatively; other clinical sampleswere inoculated, qualitatively. Identification of S. maltophilia isolates was performed byconventional methods and fully automated microbiology system. Antimicrobial susceptibilitytests were performed by Kirby-Bauer’s disk diffusion method and by broth dilution.Results: A total of 60 S. maltophilia strains isolated from clinical specimens as 24 urine, 15blood, 11 sputum, four synovial fluids, three cerebrospinal fluids, two wound swabs and onemiddle ear materials. The resistance rates against antibiotics were detected as 85% (n=51) forpiperacillin-tazobactam, 75% (n=45) for levofloxacin, 73% (n=44) for ciprofloxacin, 57%(n=34) for trimethoprim-sulfamethoxazole, 5% (n=3) for meropenem and imipenem, and 0%(n=0) for amikacin.Conclusion: In this study, it was detected that piperacillin-tazobactam can be used as analternative option other than trimethoprim-sulfamethoxazole, for the treatment of infections dueto S. maltophilia at least in our region
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    NASOPHARYNGEAL CARCINOMA IN THE ETIOLOGY OF FEVER OF UNKNOWN ORIGIN
    (Nobel Ilac, 2010) Uluğ, Mehmet; Çelen, Mustafa Kemal; Geyik, Mehmet Faruk; Tekin, Recep; Ayaz, Celal
    Fever of unknown origin is defined as a temperature higher than 38.3 degrees C lasting three weeks or longer and not beind diagnosed even after one week of study in-hospital settings. Infections and malignancies had been the most common causes of fever of unknown origin overall. Nasopharyngeal carcinoma,constituting less than 0.03% of all malignant tumors and only 2% of all head and neck cancer. Ebstein Barr virus infection consumption of smoked and salted fish and vitamin-C deficient diet have been blamed in its etiology. In this study,we present two cases who were admitted to our clinic with fever of unknown origin initially and later diagnosed with nasopharyngeal carcinoma atypically progressing.
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    Surveillance of Nosocomial Infections in General Surgery Unit: Data of Ten Years Period
    (Düzce Üniversitesi, 2010) Geyik, Mehmet Faruk; Aldemir, Mustafa; Tekin, Recep; Çelen, Mustafa Kemal; Girgin, Sadullah; Hosoğlu, Salih; Ayaz, Celal
    Aim: The aim of this study is to evaluate the epidemiologic data of nosocomial infection (NI)occurring in the General Surgery Unit (GSU).Method: This study was performed between January 1997 and December 2006. The surveillancemethod was active, prospective, and based on laboratory and patient. NIs were defined accordingto Centers for Diseases Control and Prevention criteria (CDC).Results: During the ten-year period, 305 NI episodes were detected in 290 patients. The overallincidence rates and incidence densities of NIs were 2.0% and 2.3/1,000 patient-day respectively.The most common NIs by primary site were surgical site infections, urinary tract infections,and pneumonia. The most prevalent microorganisms were Escherichia coli (36.8%),Staphylococcus aureus (17.7%) and Pseudomonas aeruginosa (10.5%). Meticillin resistanceamong S. aureus isolates was 76%. Meropenem and amikacin were the most effective agentsagainst to Gram-negative bacteria. Conclusion: In order to detect of the variation and trends of NIs, the data of surveillanceactivities must be evaluated decisively and regularly with collaboration among infection controlteam, Infectious Disease clinic, and GSU
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    Surveillance of nosocomial infections in general surgery unit: Data of ten years period
    (2010) Üstün, Cemal; Geyik, Mehmet Faruk; Aldemir, Mustafa; Tekin, Recep; Çelen, Mustafa Kemal; Girgin, Sadullah; Ayaz, Celal
    Aim: The aim of this study is to evaluate the epidemiologic data of nosocomial infection (NI) occurring in the General Surgery Unit (GSU). Method: This study was performed between January 1997 and December 2006. The surveillance method was active, prospective, and based on laboratory and patient. NIs were defined according to Centers for Diseases Control and Prevention criteria (CDC). Results: During the ten-year period, 305 NI episodes were detected in 290 patients. The overall incidence rates and incidence densities of NIs were 2.0% and 2.3/1,000 patient-day respectively. The most common NIs by primary site were surgical site infections, urinary tract infections, and pneumonia. The most prevalent microorganisms were Escherichia coli (36.8%), Staphylococcus aureus (17.7%) and Pseudomonas aeruginosa (10.5%). Meticillin resistance among S. aureus isolates was 76%. Meropenem and amikacin were the most effective agents against to Gram-negative bacteria. Conclusion: In order to detect of the variation and trends of NIs, the data of surveillance activities must be evaluated decisively and regularly with collaboration among infection control team, Infectious Disease clinic, and GSU. © 2010 Düzce Medical Journal.