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    Increased mean platelet volume in patients with vestibular migraine
    (2020) Çavuş, Mehmet Emin; Tanyel, Talip Talha; Akcan, Fatih; Bayır, Ömer; Gökkurt, Didem
    Objectives: The purpose of this study was to investigate relation between mean platelet volume, plateletdistribution width, platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio and vestibular migraine.Methods: This study was planned in prospective manner and conducted in Ankara Polatlı State Hospitalbetween April 2017 and May 2018. Thirty patients diagnosed with vestibular migraine and thirty healthy, ageand sex-matched subjects were enrolled to the study. Mean platelet volume, platelet distribution width, plateletcount, neutrophil count and lymphocyte count in blood samples were measured.Results: The mean age of the patients with vestibular migraine was 39.90 ± 7.16 and the study group consistedof 11 males and 19 females. The mean platelet volume and platelet distribution width values in patients withvestibular migraine were significantly higher than the control group (p < 0.001). There were no difference onmean neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values between patient group and controlgroup.Conclusions: We found a positive relation of increased levels of mean platelet volume and platelet distributionwidth with vestibular migraine. Higher mean platelet volume is associated with atherosclerosis andthromboembolism. Vascular pathologies are blamed for both headache syndromes like migraine and vertiginoussyndromes. This theory supports our study but pathophysiological mechanism is not clear.