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    The Evaluation of The Prognostic Effect of NT-Pro BNP Levels and Left Ventricular Ejection Fraction in Acute Decompansated Heart Failure During Levosimendan Treatment
    (Düzce Üniversitesi, 2009) Izgu, İbrahim; Tacoy, Gulten; Yazıcı, Guliz Erdem; Tavil, Yusuf; Tımurkaynak, Timur; Demırkan, Deniz
    Aim: To evaluate the prognostic effect of serum NT-proBNP levels and left ventricular ejection fraction in patients who have acute decompansated heart failure and receive levosimendan treatment. Method: Fourteen patients (10 male (71,4 %), 4 female (28,6%)) with heart failure who have low cardiac output findings and unresponsive to intravenous and vasodilator therapy, functional capacity NHYA class IV were enrolled into the study. Clinical status, systolic (SBP) and diastolic blood (DBP) pressures as hemodynamic parameters, measurements of serum NT-proBNP, BUN, Cre, Na+, K+, AST, ALT, Hb, Htc levels; left ventricular end diastolic (LVEDD) and systolic (LVESD) diameters, end diastolic (LVEDV) and end systolic (LVESV) volumes, cardiac output and ejection fraction (LVEF) by echocardiographic evaluation were obtained before and after levosimendan infusion Results: Treatment with levosimendan in decompansated heart failure exerts significantly reduction in LVEDD, LVEDV, LVESV, DBP, serum NT-proBNP levels and increase in LVEF (p