Yazar "Sonmez, Cemil Isik" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    A NEW MARKER PERILIPINE COUNTERWORK WITH VITAMIN D THROUGH REGULATION LIPID METABOLISM IN OBESES
    (Carbone Editore, 2020) Sahin, Ibrahim Ethem; Alpay, Merve; Sonmez, Cemil Isik
    Introduction: Vitamin D deficiency and obesity are common controversial health problems. Vit D supports lipolysiv from the outside, stimulates lipogenesis. Perilipine protein, which allows the use of lipids in the mitochondria in cell. Our main aim of this research was to control obesity prognosis monitoring Perilipine levels related by WO treatments. Methods: During winter months, patients that have admitted the hospital whose ages ranged from 18 to 65 years at 80 obese and normal BMI individuals were included the study. Blood samples from patients were taken and measured for VitD level. Experimental groups arranged again according to BMI and VitD results. Results: The mean age of the patients was +/- 34(18-65). After organized samples, vitamin D deficiency group which 25-OH D levels were < 20 nglml, were 37.75 +/- 4.79 higher Perilipine levels than normal VItD individuals. However, Perilipine levels were increased in obese patients display positive correlation with BMI. Discussion: These results were indicated that high frequency of vitamin D deficiency drives obesity relatively especially in winter months. The research findings suggest that Perilipine expression has direct correlation by vitamin D alteration. For this purpose, Perilipine can be a novel marker to prevent obesity and should he controlled previously identified obesity groups treated new methods of VitD uptake.
  • Küçük Resim
    Öğe
    THE RELATIONSHIP BETWEEN THE LEVEL OF SERUM FERRITIN AND METABOLIC PARAMETERS IN OBESE PATIENTS
    (Carbone Editore, 2020) Ozbey, Zemze; Sonmez, Cemil Isik; Baser, Duygu Ayhan
    Objective: In this study, we aimed to evaluate the effect of obesity on serum ferritin levels and the relationship between serum ferritin levels and metabolic parameters according to gender-associated differences. Methods: This retrospective and cross-sectional study included 935 pre-obese and obese individuals who applied to the Obesity Policlinic and met the inclusion criteria. Data were obtained from patient files and hospital database. The patients were divided into 4 groups according to WHO's obesity classification and evaluation was made according to gender.The relationship between ferritin and metabolic parameters of all patients were examined. The observational statistical analysis of the data stored was made through a statistical software. Results: 862% of the study consisted of women. There was a significant difference between ferritin and BMI in women (p <0.05), but not in men. In females, ferritin was positive among the obese groups (p <0.05), but there was an increase from group la to group 4a in men, although there was no significance in men. Significance was found between ferritin and APG, uric acid, creatinine, ALT, TC, LDL-C, TG in females and ferritin and ALT in males (p <0.05). Conclusion: Obesity and increased ferritin have been shown to be related to some metabolic parameters in comorbidiries caused by obesity mainly in women. So the anemia should not be ruled out by looking at the ferritin level only in obese patients that we frequently encounter in primary care. And also when evaluated the metabolic parameters of obese and preobese patients, it is very important to pay attention to the gender factor.