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Öğe Clinical importance of preoperative fine needle aspiration biopsy and computed tomography in parotid gland masses(2016) Şahin, Ender; Ünlü, İlhan; Ünlü, Elif Nisa; Kaptan, Zeynep; Uzunkulaoğlu, Hakkı; Samim, Ethem Erdal; Karadavut, YunusObjectives. To determine the diagnostic value of fine needle aspiration biopsy (FNAB) and computedtomography (CT) in parotid masses in the basis of postoperative histopathological results. Methods. The recordsof 68 patients diagnosed with a parotid mass and undergone parotis surgery between November 2004 andFebruary 2011 were evaluated retrospectively. Preoperative FNAB and the CT findings were compared withpostoperative histopathological findings. Results. The study included 36 (58%) female and 26 (42%) malepatients. The mean age of the patients was 43.9 years. No statistically significant difference was detected withregards to the performances of both FNAB and the CT (p0.797). When it was evaluated in a detail, theperformance of parotid CT(81.82%) to diagnose a mass in parotid gland was relatively better than FNAB(72.73%). The performance of FNAB (94.12%) to detect healthy ones was also greater than parotid CT (90.2%).Conclusion. We emphasize that preoperative FNAB and parotid CT should be performed to the patients witha parotid mass. The use of these two tests together can minimize the risk rate have been proved.Öğe Comparison of effect ofvaccination against polysaccharide streptococcus pneumoniae and haemophilus influenzae and ventilation tube ino titis media with effusion(Turkiye Klinikleri, 2014) Ünlü, İlhan; Samim, Ethem ErdalObjective: Otitis media with effusion (OME) is a common childhood infection. Streptococcus pneumoniae and Haemophilus influenzae are very common bacterial pathogens in the etiology of OME. The purpose of the study is providing immunization against these pathogens and to see how it affects the course and recurrence of OME according to insert ventilation tube. Material and Methods: Ventilation tube was performed to 45 patients with OME between the ages of 2 to 13.H. influenzae type b conjugate vaccine and Pneumococcal polysaccharide vaccine containing 23 serotypes were applied together with an interval of 1 week to 35 patients between the ages of 2 to 13 who did not accept the application of ventilation tube. Patients with systemic diseases, immunodeficiency, allergy history, craniofacial malformations (for example, cleft palate, retrognathia, choanal atresia), previously application of the tube or history of ear surgery were excluded from the study. All patients were evaluated with pneumotoscopy and tympanometry at first week and at 1, 3, 6, 9, 12th months after the therapy and the findings were recorded. Results: The best results of vaccination group (VG) were obtained at the end of 12th month. Complete remission was observed in 24 (68.6%) patients and partial remission was observed in one patient at the end of 12th month. Also complete remission in 28 (62.2%) patients and partial remission in 3 (6.7%) patients was observed at the tube group (TG). Statistical analysis showed no significant difference between AT and TG in terms of healing rates (p?0.05). Conclusion: Vaccination of the patients with OME against S. pneumoniae and H. influenzae reduces the progression and recurrence of OME, but it's not more effective than ventilation tube. © 2014 by Türki ye Klinikleri.Öğe The effect of 2100 MHz radiofrequency radiation of a 3G mobile phone on the parotid gland of rats(W B Saunders Co-Elsevier Inc, 2015) Aydoğan, Filiz; Ünlü, İlhan; Aydın, Emine; Yumuşak, Nihat; Devrim, Erdinç; Samim, Ethem Erdal; Seyhan, NesrinPurpose: We aimed to evaluate the effect of 2100 MHz radiofrequency radiation on the parotid gland of rats in short and relatively long terms. Material and methods: Thirty Wistar albino rats were divided into four groups. Groups A and B served as the control groups (for 10 days and 40 days, respectively), and each group included six rats. Groups C and D were composed of nine rats each, and they were the exposure groups. The rats were exposed to 2100 MHz radiofrequency radiation emitted by a generator, simulating a third generation mobile phone for 6 hours/day, 5 days/week, for 10 or 40 days. Following exposure, the rats were sacrificed and parotid glands were removed. Histopathological and biochemical examinations were performed. Results: Although there were no histopathological changes in the control groups except for two animals in group A and three animals in group B, the exposure groups C (10 days) and D (40 days) showed numerous histopathological changes regarding salivary gland damage including acinar epithelial cells, interstitial space, ductal system, vascular system, nucleus, amount of cytoplasm and variations in cell size. The histopathological changes were more prominent in group D compared to group C. There was statistically significant different parameter regarding variation in cell size between the groups B and D (p = 0.036). Conclusion: The parotid gland of rats showed numerous histopathological changes after exposure to 2100 MHz radiofrequency radiation, both in the short and relatively long terms. Increased exposure duration led to an increase in the histopathological changes. (C) 2015 Elsevier Inc. All rights reserved.Öğe The Use of Glass Ionomer Cement in the Reconstruction of the Dorsal L-Strut: An Experimental Study on Rabbits(Wiley-Blackwell, 2014) Aydoğan, Filiz; Tüzüner, Arzu; Ünlü, İlhan; Demirci, Şule; Aydın, Emine; Yumuşak, Nihat; Samim, Ethem ErdalObjectives/Hypothesis: This experimental study in a rabbit model aimed to investigate the use of glass ionomer cement as a tissue adhesive on the dorsal L-strut. Study Design: Sixteen adult male New Zealand White rabbits were used. The rabbits were equally divided into two groups as the control and the study groups. Methods: The nasal septum was exposed through a superior approach. A graft was harvested preserving an L-strut cartilage. In the control group, a vertical incision was performed on the dorsal part of the L-strut to divide it into two cut ends, and the graft was sutured to the cut ends with 5-0 polydioxanone suture. In the study group, the reconstruction of the dorsal L-strut was made by fixing the graft to the cut ends with glass ionomer cement as the tissue adhesive. At 2 months, the rabbits were sacrificed. The nasal septum was removed for histopathological examination. Results: No foreign body giant cells or acute inflammation were determined in the rabbits. The study group had less pronounced chronic inflammation. Comparison of the groups revealed that parameters regarding vascularization, cartilage proliferation, and new cartilage cells were statistically significant different between the two groups (P=.010, P=.010, P=.028, respectively). More vascularization, cartilage proliferation, and new cartilage cells were seen in the study group. Conclusions: Glass ionomer cement was effective for the reconstruction of the dorsal L-strut without any foreign body reaction, cartilage necrosis, or marked inflammation in rabbits, and it may be a potentially beneficial alternative to suture fixation.