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Öğe Alopecia areata in Turkey: demographic and clinical features(Wiley, 2008) Kavak, Ayşe; Yeşildal, Nuray; Parlak, Ali Haydar; Gökdemir, Gonca; Aydoğan, I.; Anul, H.; Baykal, CanBackground Alopecia areata is a complex genetic disease with still many unknown aspects, and many studies have been tried to find some clues about it. Objective We aimed to investigate the demographic and clinical characteristics of alopecia areata in Turkish patients. Methods Demographic data, localization, attack number in addition to some parameters such as disease duration, severity, age of onset, family history and ophiasis pattern were evaluated in 539 alopecia areata patients. Results The male to female ratio was 1.6 : 1. Occipital and beard-moustache areas were mostly affected. Positive family history was noticed in 24.1% of the patients. The age of onset was earlier in women than in men (P = 0.04). Severe forms showed more persistent (>= 1 year) disease duration (P = 0.00). Ophiasis was more common in severe, long duration (>= 1 year) and early onset (<= 18 years) disease (P = 0.00 for all parameters). Childhood alopecia areata (<= 18 years) was also associated with long duration of the disease (P = 0.016) and positive family history (P = 0.008) when compared with adult onset (> 18 years) alopecia areata.Öğe Dermatophytoses in forestry workers and farmers(Blackwell Verlag Gmbh, 2005) Şahin, İdris; Kaya, Demet; Parlak, Ali Haydar; Öksüz, Şükrü; Behçet, MustafaTo assess the frequency of superficial mycoses in forestry workers and farmers in the rural region of Duzce, a total of 467 residents of the rural region were examined for dermatomycosis infection. Of these, 349 were forestry workers and 118 farmers. All specimens collected were analysed by direct microscopy and culture. Tinea pedis et manus was found in 23 (19.4%), and onycomycosis in 21 (17.7%) farmers. Tinea pedis et manus was found in 50 (14.3%), and onycomycosis in 28 (8%) forestry workers. One tinea corporis, two tinea inguinalis and two erosio interdigitalis cases were determined in the farmer group but no cases of tinea corporis, tinea inguinalis, or erosio interdigitalis were found in the forestry group. In total, five tinea versicolor cases were found in the two groups on clinical examination but no agent positivity was yielded in mycological cultures. The most frequently isolated agent in the two groups was Trichophyton rubrum. The frequencies of superficial mycosis and onychomycosis were found to be higher in the farmer group than in the forestry group, although similar aetiological agents were isolated in both groups. The farmers had greater rates of contact with pathogenic fungi present in soil as well as from infected farm animals than the foresters; furthermore, animal husbandry, and the wearing of rubber shoes and nylon socks were more frequent in the farmer group. These results suggest that habits such as the wearing of rubber shoes and nylon socks, and the practice of animal husbandry may be the most important factors in determining the frequency of superficial mycoses and aetiological agents in forestry workers and farmers. To our knowledge, there is no previous report about dermatophytoses in forestry workers.Öğe Is a case of sweet's syndrome associated with Behçet's disease?(2003) Parlak, Ali Haydar; Kavak, Ayşe; Alper, Murat; Tunç, MuratOral aphthae, genital ulceration, uveitis, positive pathergy test and cutaneous vasculitis are diagnostic criteria of Behçet's disease. Similar symptoms may also appear in Sweet's syndrome. We report here a case of Sweet's syndrome associated with oral aphthae, erythema nodosum, episcleritis and positive pathergy test, with a history of upper respiratory tract infection and drug administration. She did not have any symptoms of Behçet's disease except for recurrent oral aphthae and arthralgia previously. Whether she has Sweet's sydrome in Behçet's disease or an isolated entity has been also discussed.Öğe Measurement of epidermal thickness in a patient with psoriasis by computer-supported image analysis(Associacao Brasileira de Divulgacao Cientifica, 2004) Alper, Murat; Kavak, Ayşe; Parlak, Ali Haydar; Demirci, Recep; Belenli, İbrahim; Yeşildal, NurayThe aim of the present study was to measure full epidermal thickness, stratum corneum thickness, rete length, dermal papilla widening and suprapapillary epidermal thickness in psoriasis patients using a light microscope and computer-supported image analysis. The data obtained were analyzed in terms of patient age, type of psoriasis, total body surface area involvement, scalp and nail involvement, duration of psoriasis, and family history of the disease. The study was conducted on 64 patients and 57 controls whose skin biopsies were examined by light microscopy. The acquired microscopic images were transferred to a computer and measurements were made using image analysis. The skin biopsies, taken from different body areas, were examined for different parameters such as epidermal, corneal and suprapapillary epidermal thickness. The most prominent increase in thickness was detected in the palmar region. Corneal thickness was more pronounced in patients with scalp involvement than in patients without scalp involvement (t = -2.651, P = 0.008). The most prominent increase in rete length was observed in the knees (median: 491 ?m, t = 10.117, P = 0.000). The difference in rete length between patients with a positive and a negative family history was significant (t = -3.334, P = 0.03), being 27% greater in psoriasis patients without a family history. The differences in dermal papilla distances among patients were very small. We conclude that microscope-supported thickness measurements provide objective results.Öğe Preliminary study among truck drivers in Turkey: Effects of ultraviolet light on some skin entities(Blackwell Publishing, 2008) Kavak, Ayşe; Parlak, Ali Haydar; Yeşildal, Nuray; Aydoğan, İlker; Anul, HüseyinIn this study, we aimed to compare driver (left) and opposite (right) sides for some skin entities in drivers. We also evaluated the effect of occupational duration, age and skin type among this population. One hundred and fortyeight truck drivers were included in this study. Sun exposed areas were classified. Dermatological entities such as actinic keratosis, solar lentigo, seborrheic keratosis, melanocytic nevus, spider angioma, ephelid, basal cell carcinoma (BCC), squamous cell carcinoma, and melanoma were compared to driver and right sides. In addition, drivers were divided into two subgroups according to: (i) age (subgroups A1, 20-40 years, and A2, >40 years); (ii) occupational duration (subgroups O1, 1-10 years, and 02, >1 0 years); and (iii) skin type (subgroups S1, skin types I and II, and S2, skin types III and IV. Each of the two subgroups were compared with respect to the total prevalence (left and right sides) of lesions excluding the location. Seborrheic keratosis and lentigo solaris were found to be increased on the driver side of the face (P = 0.00) and ear (P = 0.013), respectively. Statistically significant increases of lesions on the driver side were determined according to the subgroups: melanocytic nevi were found to be increased on the driver side in A1 (P = 0.00), A2 (P = 0.00), 02 (P = 0.00), S1 (P = 0.00) and S2 (P = 0.006) groups; actinic keratoses were found to be significantly increased on the driver side in A2 and 02 groups (P = 0.03 for both).Öğe Seroprevalence of Borrelia burgdorferi infection among forestry workers and farmers in Duzce, north-western Turkey(Edizioni Int Srl, 2008) Kaya, Ayşe Demet; Parlak, Ali Haydar; Öztürk, Cihadiye Elif; Behçet, MustafaBorrelia burgdorferi infection is the most frequent tick-transmitted disease worldwide. Our aim was to assess the seroprevalence of B. burgdorferi infection among forestry workers and farmers in Duzce, in the north-west region of Turkey Blood samples from 349 forestry workers and farmers and 193 healthy blood donors were obtained to determine the presence of antibodies to B. burgdorferi. A two-step testing strategy was used; the sera were initially tested by ELISA and then by Western blot (WB) IgG. Demographic data regarding residence, age, gender, profession, tick bite history, contact with animals, and symptoms involving the skin, nervous system, and osteoarticular system were collected by questionnaire. All results were evaluated statistically using the chi(2) test. The seroprevalence of B. burgdorferi was 10.9% (n=38) in forestry workers and farmers and 2.6% (n=5) in blood donors by ELISA, with a statistically significant difference (p < 0.001). Seropositivity rates were related to age, gender, and common risk factors for the disease. IgG seropositivity was confirmed in four (1.1%) sera by WB. In this first seroepiderniological report from the northwest region of Turkey, tick bite exposure was found to be high, whereas B. burgdorferi infection was not common. Preventive measures against tick exposure and further studies to determine the distribution of Lyme disease in Turkey are proposed.Öğe Subepidermal calcified nodule(Univ West Indies Faculty Medical Sciences, 2003) Alper, Murat; Parlak, Ali Haydar; Belenli, Olcay KandemirSubepidermal calcified nodules are rarely seen and are classified under, idiopathic subepidermal calcifications. They commonly affect children. It is most frequently encountered in the face, and it is less common in the extremities. Here, we-present a case where the lesion was, localized on the knees of a 23-year-old female patient.Öğe Subungual osteochondroma - A diagnostic dilemma(Amer Podiatric Med Assn, 2006) Tüzüner, Tolga; Kavak, Ayşe; Parlak, Ali Haydar; Üstündağ, NilOsteochondroma is the most common skeletal neoplasm of all benign bone tumors. However, it rarely occurs subungually. In this location, the lesion may penetrate the skin, causing nail deformity, and can easily be misdiagnosed. We report two cases of subungual osteochondroma of the distal phalanges of the first toes with cutaneous penetration and discuss the clinical, histologic, and radiographic features and the treatment options.Öğe Unilateral linear verrucous epidermal nevus of the face and the oral mucosa(Lippincott Williams & Wilkins, 2005) Özçelik, Derya; Parlak, Ali Haydar; Öztürk, Ayhan; Kavak, Ayşe; Çelikel, Nuran…