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    Analysis of the effects of hypothalamic-pituitary-adrenal axis activity in menstrual cycle on ankle proprioception, dynamic balance scores and visual-auditory reaction times in healthy young women
    (Jmni, 2021) Senol, Deniz; Ucar, Cihat; Toy, Seyma; Kisaoglu, Aysegul; Ozbag, Davut; Ersoy, Yuksel; Yildiz, Sedat
    Objectives: Menstrual cycle (MC) can affect not only the female reproductive system, but also functions such as neuromuscular performance. For this reason. the aim of this study is to investigate the effect of hypothalamic-pituitary-adrenal axis (HPA) activity in MC on proprioception, balance and reaction times. Methods: For cortisol analysis, saliva samples were taken from the same women (n=43) in the four phases of MC. While State Trait Anxiety Inventory-I (STAI-I) was applied in each phase to support cortisol analysis, pain was measured with visual analogue scale (VAS). Proprioception, dynamic balance, visual and auditory reaction times (VRT-ART) measurements were made in the four phases of MC. Results: Cortisol, STAI-I and VAS scores, angular deviations in proprioception measurements, dynamic balance scores, VRT and ART measurements were found to show statistically significant difference between MC phases (p<0.05). As a result of the post hoc test conducted to find out which MC phase the statistical difference resulted from, it was found that statistically significant difference was caused by the mensturation (M) phase (p<0.05). Conclusions: It was found that neuromuscular performance and postural control was negatively affected by HPA axis activity in M phase of MC and by pain, which is a significant menstrual symptom.
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    Evaluation of early thyroidectomy complications
    (Bayrakol Medical Publisher, 2022) Karatas, Turgay; Selcuk, Engin Burak; Karatas, Mehmet; Yildirim, Atilla; Ozbag, Davut; Cay, Mahmut; Senol, Deniz
    Aim: Our aim in this study is to reveal the relationships between patient findings, surgical methods and early thyroidectomy complications. Material and Methods: The files and operative notes of 308 patients who underwent thyroidectomy within 10 years were reviewed retrospectively. Gender, age, preoperative diagnosis, primary or reoperated cases, the type of thyroidectomy [ bilateral subtotal (BST), bilateral total (BTT), unilateral subtotal (UST) and unilateral total (UTT)] and early postoperative complications (hypocalcemia, bleeding, nervus laryngeus recurrens (NLR) injury, infection and seroma) were recorded. The peculiarity of this study is that NLR neuromonitoring was not used in thyroidectomy operations. Results: Of the 308 patients who underwent thyroidectomy, 287 were females and 21 were males. Two hundred eighty three cases of multinodular goiter, 18 cases of nodular goiter and 7 thyroid cancers were operated; 180 BTT, 100 BST, 17 UTT + UST, 7 UST and 4 UTT were applied. Complications were seen in a total of 20 (6.49%) patients who underwent 19 BTT and 1 BST. The only complication in BST was bleeding. There were 10 (3.24%) hypocalcemia, 4 (1.29%) bleeding, 2 (0.649%) NLR injury, 2 (0.649%) infections and 2 (0.649%) seromas. In terms of the frequency of early thyroidectomy complications, hypocalcemia was the first (P=0.0047). In addition, the rates of hypocalcemia and NLR injury were higher in reoperated patients than in primary patients (P<0.05). Discussion: The most common complication was hypocalcemia. NLR injury and hypocalcemia rates were higher in reoperated cases who underwent BTT.
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    Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography
    (Turkish Neurosurgical Soc, 2023) Ciftci, Rukiye; Cetin, Aymelek; Ulubaba, Hilal Er; Senol, Deniz; Cinarli, Fahri Safa; Ozbag, Davut
    AIM: To examine the morphometric properties of the vessels forming the Willis polygon (WP) in patients with type 2 diabetes mellitus (T2DM) and hypertension (HT) and compare them with healthy individuals.MATERIAL and METHODS: Cranial Tomography Angiography (CTA) of 168 individuals were analyzed retrospectively. The individuals included in the study were divided into four groups according to the diagnosis. Group 1 included 40 individuals who were diagnosed with HT, Group 2 included 43 individuals who were diagnosed with DM, Group 3 included 42 individuals who were diagnosed with DM and HT, and Group 4 was the control group and included 43 individuals. The diameter and length measurements of the vesselsRESULTS: According to the results of the Kruskal Wallis H test, in female patients statistically significant differences were detected in the diameter measurements of the right and left A1 segment of the ACA, the diameter measurement of the left A2 segment, the diameter measurements of the right and left P1 and P2 segments of the ACP, the diameter measurements of the right and left AComP. (p<0.05), in male patients statistically significant differences were found in the diameter of the right A1 segment of the ACA, the diameter and segment length measurements of the right and left P1 segments of the ACP, of the right and left P2 diameter measurements, and segment length measurements of the left AComP (p<0.05).CONCLUSION: We also found that the vessel diameters were similar in the HT, DM and HT+DM groups, and smaller than the control group. In addition, we think that knowing WP morphometric measurements will both guide the radio-anatomical evaluations to be made and increase the level of microanatomical knowledge in surgical treatment.