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  • Küçük Resim
    Öğe
    Hastane Biyokimyasal Verilerinden Sağlıklı Alt Grubun Belirlemesi: Bhattacharya Prosedürü
    (Düzce Üniversitesi, 2015) Orekici Temel, Gülhan; Ovla, Havva; Derici Yıldırım, Didem; Kalafat, Hakan
    Since biochemical tests play an important role in the decisions of clinicians, it become necessary for each region andeach laboratory to have different biochemical results. When the reference population is obtained from hospital data, thehealthy and the diseased groups are also mixed. By using Bhattacharya procedure, it is possible to have a healthy subgroup out of the mixed data. The main objective of this study is to introduce Bhattacharya procedure that will providea healthy selection of population while calculating the reference interval by using hospital data, and to have a practicefor Aspartat Transaminase (AST) parameter. Big data set is required in order to use Bhattacharya method (n?8000).Aspartat Transaminase (AST) data of 40.486 registered individuals applying only once to the polyclinic of Health,Research and Application Hospital of Mersin University, Clinic Biochemical Laboratory is used in this study. Referenceinterval is also calculated by using the nonparametric method and the same data. In the nonparametric method, thereference interval is calculated in the range of [12.28-49.00] with 95% confidence. According to Bhattacharya method,it is calculated as [7.10-32.26]. The comparison of the results shows that in Bhattacharya method, the reference intervalis narrower in comparison to the nonparametric method