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Öğe Congenital Muscular Torticollis in Children: Analysis of 12 Delayed Cases(Düzce Üniversitesi, 2008) Öztürk, Hayrettin; Okur, Hanifi; Öztürk, Hülya; Çiğdem, Murat Kemal; Duran, Hatun; Önen, Abdurrahman; Dokucu, Ali İhsanPurpose: The aim of this study was to estimate the records of patients treated for congenital muscular torticollis (CMT) in the period between 1986 and 2005. At this point we report our clinical experience with delayed CMT in the light of current literature. Methods: We retrospectively evaluated the records of our patients in terms of age, sex, clinical presentation, localization of the lesion, diagnostic tests, additional abnormalities, findings at operation and surgical procedures. Results: The mean age of the patients (7 girls, 5 boys) was 6.7 years (range: 1.5- 12 years). Most of the lesions were seen on the left aspect of the neck (58%). The most encountered complaint at application was restriction of neck motion (83%). Sternocleidomastoid tumor accounted for only 17% of the patients’ complaints. All patients in this study were treated by surgical intervention. Conclusions: In this study, neck motion and head tilt showed marked improvement with surgical and conservative treatment in majority of children with CMT who admitted to the hospital latelyÖğe Differential Expression of CD34, S100, and c-Kit in Interstitial Cells of Cajal in Infantile Hypertrophic Pyloric Stenosis - Immunochemical Study(Wroclaw Medical Univ, 2009) Öztürk, Hülya; Öztürk, Hayrettin; Yılmaz, Fahri; Okur, Hanifi; Otçu, Selçuk; Dokucu, Ali IhsanBackground. The pathogenesis of infantile hypertrophic pyloric stenosis (IHPS) is poorly understood although many hypotheses have been proposed. Objectives. Assessment whether the differential expression of c-Kit, CD34, and S100 may be involved in the development of IHPS. Material and Methods. Specimens from 14 infants with IHPS and seven control subjects were immunohistochemically stained for c-Kit, CD34, and S100. The numbers of CD34(+), S100(+), and c-Kit(+) cells in five random fields per specimen were compared via light microscopy (x200). Results. In normal pyloric tissue, specific and intense c-Kit immunoreactivity was observed in the muscle layers and moderate staining was observed around the myenteric plexus. In IHPS patients, c-Kit+ cells were either absent or markedly reduced around the myenteric plexus. In control and IHPS patients, CD34(+) cells were not observed around the myenteric plexus. In the vascular endothelium, moderate CD34 staining was observed in specimens from control subjects, whereas intense staining was observed for IHPS patients. In normal pyloric tissue, moderate S100 immunoreactivity was observed in the muscle layers and intense staining was observed in the myenteric plexus. In IHPS patients, few S100(+) cells were observed in the pyloric muscle layers and S100 immunoreactivity decreased markedly around the myenteric plexus. Conclusions. These results suggest that the numbers of c-Kit(+) and S100(+) cells are markedly decreased in the pyloric muscle layers and around the myenteric plexus in IHPS patients. Thus a lack of c-Kit and S100, but not CD34, expression may be a critical factor in the pathogenesis of IHPS and may serve as a useful prognostic tool in the treatment of this disease (Adv Clin Exp Med 2009, 18, 1, 33-39).Öğe Esophageal duplication cyst: Another cause of respiratory distress in children(Düzce Üniversitesi, 2008) Öztürk, Hayrettin; Karaaslan, Kazım; Okur, Hanifi; Öztürk, HülyaEsophageal duplication cysts are rare congenital anomalies of enteric origin found in children. They are considered to be due to abnormal cannulisation of the gastrointestinal tract. Clinical symptoms depend on the size and the localization of the cysts. Respiatory symptoms are the most frequent symptoms seen in children presenting foregut duplication. In this study, we present two patients with foregut cyst was in whom dyspnea evidentÖğe The Use of Glubran 2 in Management of Cleft Palate(Düzce Üniversitesi, 2008) Öztürk, Hülya; Öztürk, Hayrettin; Duran, Hatun; Okur, HanifiAim: Cleft lip and palate are the most common congenital craniofacial anomalies in humans. Delayed complications of palatoplasty include fistulas and delayed midfacial growth disturbances. The purpose of this study is to research the activity of using tissue adhesives in blocking palatal fistula formation. Method: We reviewed 39 cases of cleft palate between January 1995 and May 2005. Clinical data included age, sex, type of cleft palate, operation technique, use of tissue adhesives and complications. Results: Operative treatment included palatoplasty in 24 patients and palatoplasty and Glubran 2 in 15. Fistulas occurred in 7(%29.1) of 24 patients that were only palatoplasty applied but there was only 1(%6.6) fistula in 15 patients that palatoplasty and Glubran 2 applied. Conclusion: Positive results, which we required from the patients with cleft palate, could be either from our clinical experience or Glubran 2 affects