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    Association of vitamin D insufficiency/deficiency with thyroid artery Doppler ultrasonography in patients with Hashimoto thyroiditis
    (Professional Medical Publications, 2017) Nalbant, Ahmet; Aydın, Ayhan; Karacan, Alper; Önmez, Attila; Tamer, Ali; Cinemre, Hakan
    Background (sic) Objective: During the course of the autoimmune thyroid diseases, ultrasonography change parallel to histopathology. Vitamin D is associated with autoimmune diseases and thus can affect thyroid blood flow. Our aim was to investigate the relationship between vitamin D insufficiency/deficiency and thyroid hemodynamic indices in patients with Hashimoto thyroiditis. Methods: A total of 93 patients who presented to Sakarya University Endocrinology outpatient clinic from April to September 2016 and diagnosed with Hashimoto thyroiditis were included in this study. Clinical and serologic data, thyroid antibodies and 25(OH)D3 were evaluated. Mean peak systolic velocity(mPSV), mean end-diastolic velocity (EDV), mean resistive index (RI) flows of superior and inferior thyroid arteries were measured with B-mode Doppler ultrasonography. Results: Vitamin D insufficiency/deficiency was detected in 59 (63.4%). TPO Ab and TgAb levels were found higher in patients with vitamin D insufficiency/deficiency. In the normal vitamin D group, superior thyroid artery mPSV (32.21 +/- 6.73cm/s) and EDV(13.27 +/- 2.80 cm/s) were higher than in the low vitamin D group [mPSV (28.32 +/- 8.99cm/s) and EDV(10.67 +/- 3.68 cm/s)] (P=0.034, P=0.001, respectively). Inferior thyroid artery EDV value was higher in the normal compared to the low vitamin D group (0.032). RI measured in all arteries were higher in the vitamin D insufficient/deficient group compared to the Vitamin D normal group (p=0.001). Conclusion: Vitamin-D insufficiency/deficiency has led to reduced parenchymal blood supply and increased micro-vascular resistance in Hashimoto thyroiditis patients.
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    Use of a portable monitoring device (Somnocheck Micro) for the investigation and diagnosis of obstructive sleep apnoea in comparison with polysomnography
    (Professional Medical Publications, 2016) Bilgin, Cahit; Erkorkmaz, Ünal; Uçar, Muhammed Kürşad; Akın, Neşe; Nalbant, Ahmet; Annakkaya, Ali Nihat
    Objective: Polysomnography (PSG) remains the gold standard for the diagnosis of obstructive sleep apnoea syndrome (OSAS). While PSG is essential for OSAS, this technique is not suitable for epidemiological investigation due to its high cost. This study aimed to compare a portable monitoring device with PSG for the measurement of parameters related to the diagnosis of OSAS in rural areas. Methods: We conducted a descriptive study of 155 patients (30 women and 125 men; mean age, 52 +/- 12 years) who visited to the Hendek Government Hospital Sleep Laboratory between February 2011 and January 2013 Apnoea hypopnea index (AHI), mean levels of O-2 (meanO(2)), desaturation index (DI), and minimum oxygen saturation (minO(2)) variations as measured using both PSG and a portable Somnocheck Micro (SM) device were compared. Results: Differences were found between the meanO(2) and DI, but not between AHI and minO(2). Differences between the methods were not desired, but the relationship between the methods was distinct and supported our hypothesis. Conclusions: The results of our study have shown that the SM portable device can be used as an alternative diagnostic tool in this population either at home or in sleep clinic.