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    Differences in Choroidal Vascularity Index Between Migraine Patients in the Attack-free Period and Normal Individuals
    (Gazi Eye Foundation, 2023) Sezer, T.; Ayaslı, A.A.H.; Meydan, B.
    Purpose: Migraine is a neurovascular disorder characterized by recurrent headaches. The relationship between migraine disease and the choroid, has been examined in an attempt to elucidate the underlying pathophysiological mechanisms. This study evaluated CT (choroidal thickness) and choroidal vascularity index (CVI) in chronic migraine patients. Materials and Methods: In this prospective study, we compared CT and CVI values of 36 chronic migraine patients (30 women and 6 men) during an attack-free period with those of 36 healthy individuals (30 women and 6 men) with no systemic or ocular disease, including headache. All patients underwent a detailed eye examination. Migraine patients were grouped as those with and without aura and were asked to rate their headache severity on visual analog scale (VAS; range 1-10) and estimate their monthly migraine frequency. Results: The mean subfoveal CT (SFCT) was 300.52 ± 88.30 µm in the migraine group and 262.85 ± 70.68 µm in the control group. The mean CVI was 71.8% ± 6.2% in the migraine group and 70.7% ± 5.3% in the control group. SFCT and CVI did not differ significantly between the migraine and control groups (p>0.05). VAS pain score was 8.17 ± 0.33 in the migraine group and was not correlated with SFCT (r=0, p=0.998) or CVI (r=-0.06, p=0.731). The monthly migraine frequency was 5.60 ± 3.60 and was not correlated with SFCT (r=-0.17, p=0.328) or CVI (r=-0.06, p=0.731). Conclusion: CT and CVI showed no significant differences from controls in chronic migraine patients during an attack-free period. © 2023 Gazi Eye Foundation. All rights reserved.