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  • Küçük Resim
    Öğe
    Does Saccharin Have Effect on Appetite, Energy Intake, and Serum Ghrelin? A Randomized, Controlled, Cross-Over Study in Healthy Males
    (Düzce Üniversitesi, 2022) Bayındır Gümüş, Aylin; Keser, Alev; Tunçer, Esra; Altuntaş Yıldız, Tuğba; Kepenekci Bayram, İlknur
    Objective: Instead of sugar, artificial sweeteners that do not contain energy are widely used. However, contrary to popular belief, artificial sweeteners are thought to affect metabolism. Thus, purpose of this present study was to evaluate effects of saccharin on serum ghrelin, appetite, and food consumption.Method: Nine healthy males aged 20-29 participated in the randomized, controlled, and cross-over study. Each participant received 300 ml water, and 300 ml water containing 75 grams sucrose and 240 milligrams saccharin. At baseline, 30th, 60th, 90th, 120th, and 180th min, Visual Analog Scale was applied to evaluate appetite, and blood samples were taken to analyze ghrelin. After 180th min, participants consumed ad libitum diet, and kept 24-hours dietary food intake records until the end of this day. Results: At 60th and 120th min, mean ghrelin level was higher in drinks containing only water and saccharin compared to drink containing sucrose (p
  • Küçük Resim
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    Evaluation of Nutritional Situations according to Anxiety Score of Students Prepared for Exam
    (Düzce Üniversitesi, 2018) Bayındır Gümüş, Aylin; Yardımcı, Hülya; Keser, Alev
    Aim: It was aimed to evaluate and interpret the relationship between anxiety score and nutritional status and some anthropometric measurements of students preparing for university admission exam in this research.Material and Methods: The study included 450 volunteers who were studying in Ankara and preparing for university admission exam, and the age range of individuals (16-19 years) was determined by the duration of research. State Trait Anxiety Inventory was used to determine anxiety levels of individuals and data were collected by researchers using a questionnaire form. SPSS statistical package program was used to evaluate data and appropriate statistical tests were used to determine relationship between variables.Results: While mean state anxiety score was not statistically significant between gender (p gt;0.05), trait anxiety score was found higher in females (p=0.004). As age increases, state anxiety scores of individuals increase (p=0.006). As number of daily consumed meals increased, state anxiety score decreases (p=0.030). State anxiety scores of those had to eat breakfast outside home were found higher than those had to eat lunch outside home (p=0.003). State anxiety score of those preferring school/course canteen when eating outside home were found lower than those preferring restaurant (p=0.026). However, when relation between daily food intake and anthropometric measurements and anxiety scores was examined, no significant relation was found except for relationships between protein intake and state anxiety score, and between male body mass index and trait anxiety score (p gt;0.05).Conclusion: The research shows that university exam increases the level of anxiety in students and there are significant relationships between anxiety scores and some nutritional habits and anthropometric measures.
  • Küçük Resim
    Öğe
    Fazla Kilolu ve Obeziteli Çocuklarda D Vitamini Düzeyi ile İnsülin Direnci Arasındaki Korelasyonunun Değerlendirilmesi
    (Düzce Üniversitesi, 2023) Tunçer, Esra; Keser, Alev; Ünsal, Emine Nüket; Odabaşı Güneş, Sevinç; Akın, Onur
    Amaç: Bu çalışmada fazla kilo ve obezitesi olan çocuklarda D vitamini düzeyleri ile insülin direnci parametreleri arasındaki ilişkinin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntemler: Çalışmaya 6-17 yaş aralığında, %64,4% (n=112) kız ve %35,6 (n=62) erkek, toplam 174 çocuk dahil edilmiştir. Katılımcılar, Dünya Sağlık Örgütü beden kitle indeksi (BKİ) sınıflaması kriterlerine göre normal (%29,9; n=52), fazla kilolu (%23,6; n=41) ve obezite (%46,5; n=81) olmak üzere üç gruba ayrılmıştır. Katılımcıların insülin direnci durumları, insülin direncinin homeostatik model değerlendirmesi (homeostatic model assessment of insulin resistance, HOMA-IR), açlık glikozunun insüline oranı (fasting glucose to insulin ratio, FGIR) ve kantitatif insülin duyarlılığı kontrol indeksi (quantitative insulin sensitivity check index, QUICKI) ile değerlendirilmiştir.Bulgular: HOMA-IR, fazla kilolu (2,2±1,0) ve normal kilolu (1,5±1,0) gruplara göre obezite grubunda (3,2±2,1) yüksek bulunmuştur (p lt;0,001). Fazla kilolu (0,34±0,03) ve obezite (0,33±0,03) gruplarının QUICKI değerlerinin normal kilolu (0,37±0,03) gruptan daha düşük olduğu görülmüştür (p lt;0,001). FGIR, normal kilolu grupta (16,8±10,4), fazla kilolu (10,6±6,0) ve obezite (8,5±5,5) gruplarına göre daha yüksek saptanmıştır (p lt;0,001). Çocuk ve adölesanların ortalama serum 25-hidroksivitamin D [25(OH)D] düzeyi 19,6±10,7 ng/mL olup, gruplar arasında istatistiksel olarak anlamlı bir farklılık bulunmamıştır (p=0,153). Serum 25(OH)D ile HOMA-IR değerleri arasında anlamlı, zayıf negatif (r=-0,170; p=0,025) bir korelasyon bulunmuştur. Buna ek olarak, serum 25(OH)D düzeyi ile QUICKI ve FGIR değerleri arasında zayıf pozitif istatistiksel olarak anlamlı (sırasıyla, r=0,173; p=0,022 ve r=0,173, p=0,023) bir korelasyon bulunmuştur.Sonuç: D vitamini düzeyleri insülin direnci parametrelerini etkileyebilir.