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  • Küçük Resim
    Öğe
    Effect of Intrapleural Povidone-Iodine Lavage on Thyroid Hormones in Thoracic Surgery
    (Georg Thieme Verlag Kg, 2010) Fındık, Göktürk; Gezer, Suat; Aydoğdu, Koray; Öz, Gürhan; Küçükbayrak, A.; Taştepe, İrfan; Kaya, Sadi
    Objective: Povidone-iodine (PI) is an effective disinfectant used in many surgical operations. It is known that PI is absorbed by the skin after application. Absorption is even greater in infants, as their skin is thinner and more permeable. Iodine absorption in the orbita, neck and during abdominal surgery has been previously investigated, but such a study has not been performed for the pleura, which has a greater area and capacity for absorption. In this study, we investigated the effect of intraoperative povidone-iodine lavage on thyroid hormones during thoracic surgery. Material and Method: Fifty patients without any thyroid pathology scheduled for thoracotomy were divided into 2 groups. Group A (n = 25) was given intraoperative saline lavage, while group B (n = 25) had povidone-iodine lavage. Levels of free T3 (FT3), free T4 (FT4) and thyroid-stimulating hormone (TSH) measured 1 day preoperatively and 1 day postoperatively were analyzed. Results: There was a statistically meaningful change in FT3 levels (p = 0.033) between groups, but the measured changes in FT4 and TSH levels were not statistically significant (p = 0.98 and p = 0.71, respectively). FT3 scores for group A were decreased postoperatively compared to the scores for group B, but all results were in normal ranges. In group A, the changes between preoperative and postoperative levels of FT3 and FT4 were statistically significant, while changes in TSH levels were not. In group B, changes in FT4 levels were statistically significant and changes in FT3 and TSH levels were not. Conclusions: The scores show that the iodine absorbed by the pleura during intraoperative povidone-iodine lavage has an effect on thyroid function. Intrapleural PI lavage results in changes to some thyroid hormone levels due to pleural absorption. Thus, intrapleural PI lavage should be used with care.
  • Küçük Resim
    Öğe
    Evaluatıon of platelet parameters in patıents wıth pulmonary hydatıd cyst
    (Universita Cattolica del Sacro Cuore, 2010) Küçükbayrak, Abdulkadir; Öz, Gürhan; Fındık, Göktürk; Karaoğlanoğlu, Nurettin; Kaya, Sadi; Taştepe, İrfan; Küçükbayrak, Zeynep Seçkin
    Background: Echinococcosis is a near-cosmopolitan zoonosis caused by adult or larval stages of tapeworms (cestodes) into the genus Echinococcus (family Taeniidae). It was demonstrated that platelets were capable of killing parasites independent from leukocytes. Purpose: The aim of our study was to examine mean platelet volume (MPV), platelet mass (PM) and platelet count (PC), which are practical indicators of platelet activity in preoperative and postoperative periods of the patients with hydatid cyst. Methods: In this retrospective study we evaluated 72 patients admitted to clinic of chest surgery with a diagnosis of pulmonary hydatid cyst in our hospital between January, 2006, and October, 2008. The MPV, PC, and PM were evaluated by complete blood count. PM was calculated by multiplying MPV and PLT. Results: Preoperative MPV values of the patients was found to be significantly higher than postoperative MPV values (mean: 8.07±0.83, 7.78±0.87, p= 0.002). Preoperative PM values (median: 2456.75, range: 1013.70-5046.60) was found to be higher when compared to postoperative PM values (median: 2280.80, range: 134.20-4042.60) (p= 0.039). PC values were not significantly different between two periods (Preoperative-postoperative PC mean values: 320.48±98.42, 307.29±96.45, p= 0.286). Conclusion: In this study, we demonstrated that there were no statistical difference in PC for both periods but, MPV and PM were found statistical higher than postoperative period in preoperative period. PM and PM can be used as markers of disease activity in patients who undergo surgical resection of hydatid cyst.