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    EVALUATION OF DIASTOLIC FUNCTIONS IN PATIENTS WITH BEHCET’S DISEASE: A TISSUE DOPPLER STUDY
    (Düzce Üniversitesi, 2014) Kaya, Hakan; Akçay, Ahmet; Sökmen, Abdullah; Balakan, Ozan; Köroğlu, Sedat; Nacar, Alper Buğra; Süner, Arif
    Objectives: The aim of this study was to evaluate diastolic functions and myocardialperformance index (MPI) in patients with Behcet’s disease (BD).Methods: Thirty-one BD patients (mean age 34.4±10.5 years) and 31 control subjects (meanage 33.2±10.3 years) were enrolled in this study. Left ventricular and right ventricular diastolicfunctions were assessed by conventional Doppler and tissue Doppler (TDI) methods, and MPIwas also calculated. The relationship between these parameters and disease duration wasevaluated. Results: In conventional Doppler echocardiography, Mitral A-wave velocity and decelerationtime were higher, and E/A ratio was lower in patients with BD (p=0.002, p=0.02, and p=0.006,respectively). Mitral E-wave velocity and isovolumetric relaxation time were comparablebetween groups (p gt;0.05). In TDI examination, E?/A? ratio measured from lateral mitral annuluswas lower, and A? velocity measured from lateral tricuspid annulus was higher in patients withBD (p=0.03 and p=0.02, respectively). Other mitral annular TDI (E?, A?, S?, E/E? ratio, and MPI)and tricuspid lateral annular parameters (S?, E?, E?/A? ratio and MPI) were similar between twogroups (p gt;0.05). In correlation analysis, lateral mitral annulus E?/A? ratio were inverselycorrelated with disease duration in patients with BD (r = -0.54, p=0.002). Conclusion: Left and right ventricular diastolic function parameters were significantly differentin patients with BD and controls. Diastolic function parameters were significantly associatedwith disease duration and echocardiographic follow-up may be useful in these patients

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