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    A Case That Was Not Detected Reflux Flow With Leech Therapy For 6 Months Follow-Up İn Venous İnsufficiency
    (Düzce Üniversitesi, 2020) Kaya, Abdulkadir; Sarı, Tarık; Yakişan, Rabia
    Cronic venous insufficiency is an important and frequent disease, characterized by the retrograde flow of blood in the lower extremity, is a common, debilitating disorder that is increasing in prevalence. Leech therapy is a traditional healing method for centuries and it has taken its place in modern medicine because of application areas with broad spectrum. Leech therapy is also used in the treatment of venous congestion. İn this study a case had a high level venous insufficiency and cured nearly complete with leech therapy was presented.
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    An Investigation of the Knowledge and Attitudes of Medical Faculty Students on Traditional and Complementary Medicine
    (Düzce Üniversitesi, 2021) Kaya, Abdulkadir; Günel, Mehmet Göktuğ; Nurullazade, Yashar
    Purpose: Traditional and complementary medicine, which is being used more and more all over the world, has also become widespread in our country. However, the medical school could not find enough place in the curriculum. In this study, it was aimed to show the level of knowledge and awareness of medical faculty students about traditional and complementary medicine.Method: In the study, an e-questionnaire was delivered to the 1st and 6th grade students of the medical faculty with the help of "Google Forms". A 24-question survey consisting of GETAT application methods and some descriptive questions was applied to the participants. Analyzes were analyzed by SPSS.Results: A total of 166 medical faculty students participated in the study. Most of the students were female students (% 62). Students from all classes participated in the study. The students stated that they knew the most about acupuncture and the least about plorotherapy. Nearly half of the students (46.4%) thought that GETAT applications should be included in the medical school curriculum. It was observed that towards upper grades, students stated their GETAT knowledge level more.Results and Discussion: It was observed that medical faculty students were frequently interested in GETAT applications, but they did not find their knowledge sufficient on this subject. In this sense, new education models and curriculum arrangements are needed.
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    Burnout, Intention to Resign and Related Factors among Health Professionals
    (Düzce Üniversitesi, 2024) Kaya, Abdulkadir; Kuday Kaykısız, Eylem; Öntürk Akyüz, Hatice; Köseoğlu, Mehmet
    Aim: The purpose of this study was to put forth the exhaustion state of healthcare professionals providing healthcare services in the city of Bitlis located in eastern Turkey and to compare the states of exhaustion of the healthcare professionals providing pre-hospital, first level and second level services. Additionally, determining the ratio of the intention to resign and the factors affect their intentions are among the aims of this study.Material and Methods: The study's target population comprised of all healthcare professionals working in Bitlis between 01.11.2018-01.01.2019. Age, gender, place of work, duty, marital status, number of children, smoking status, years of experience and whether they intend to resign or not of all participants were asked and Maslach burnout inventory (MBI) were filled after their consent. Data were analyzed with SPSS. P values
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    Clinical Characteristics of Cases Developing Neonatal Pneumothorax: 10 Years of Experience
    (Tıbbi Kayıtlar Derneği, 2025) Kurt, Fatih; Kaya, Abdulkadir; Kocabay, Kenan; Kaya, Murat
    Aim: Pneumothorax is a serious emergency condition that increases mortality and morbidity due to the accumulation of air between the visceral and parietal pleura layers. Neonatal pneumothorax is more frequently encountered in neonates admitted to neonatal intensive care units. It is known that the most important risk factors are prematurity and ventilation with a bag mask. Material and Method: Forty-two pneumothorax cases followed in the neonatal intensive care unit (NICU) were included in our study. The characteristics, risk factors, treatment methods and prognoses of the cases were retrospectively analyzed. Results: Twenty eight of the cases (66.67%) were male, and Pneumothorax developed within the first 3 days of life in 41 cases (97.61%). Nineteen cases (45.24%) were premature, 16 cases (38.10%) underwent resuscitation at birth, and 15 cases (35.71%) received surfactant therapy. An intercostal chest tube was placed for treatment in 34 cases (80.95%), and invasive mechanical ventilation was required in 33 cases (78.57%). Thirty six cases (85.71%) were regained the health, while those who passed away were found to be more premature. Conclusion: In our study, prematurity, resuscitation at birth, and surfactant therapy were identified as risk factors for neonatal pneumothorax. Newborns with these risk factors should be closely monitored, and neonatal pneumothorax should be kept in mind if respiratory distress develops.
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    Combination Therapy of Major Autohemotherapy and Ozonated Bagging in a Case Diagnosed with Buerger's Disease (Thromboangiitis Obliterans)
    (2023) Unal, Safa; Kaya, Abdulkadir; Ayaslı, Alper Aziz Hudai; Tunca, Bekir
    It is well known that ozone therapy provides positive results as a complementary method in peripheral obstructive arterial diseases alongside medical treatment. This article presents a case diagnosed with Buerger's disease, where rapid improvement was observed after a combination of major autohemotherapy (AHT) and ozonated bagging.
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    COVID-19 Course in Patients Receiving Pneumococcal Vaccine
    (Duzce Univ, Fac Medicine, 2021) Kaya, Abdulkadir
    Objective: The coronavirus pandemic emerged at the end of 2019 and still affects the whole world, causing severe deaths. The COVID-19 vaccine is highly anticipated, but the emphasis is also given to other vaccines. In this study, the data of 16 cases known having received a pneumococcal vaccine during the COVID-19 period were examined. Methods: Of the 200 COVID-19 cases aged over 65, data of 16 patients who have had pneumococcal vaccination were accessed using the hospital health registry and the national health system records (https://enabiz.gov.tr/). Prognostic factors and COVID-19-related findings of these patients were given in frequency tables. In addition, all raw data were presented in a detailed table. Results: Most of the cases were PCR positive (68.75%), and in 68.75% of the persons, the CT was compatible with COVID-19. Fourteen of the cases were treated by hospitalization. One patient was followed as an outpatient, and one case had already died when brought to the emergency room. Conclusions: Data on cases known to have received the pneumococcal vaccine, which became important during the COVID-19 outbreak, were presented. This work will motivate researchers to conduct large-scale studies.
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    COVID-19 Hastalarının Kan Gruplarına Göre Hemogram Parametrelerinin Değerlendirilmesi
    (2022) Gamsızkan, Zerrin; Kaya, Abdulkadir; Tuncel, Mert Can; Işık, Abdullah; Davran, Fatih; Şahin, İdris
    Amaç: COVID-19 hastalığı, tüm Dünyada birçok insanın hayatını tehdit ettiğiiçin hastaların laboratuar parametreleri her açıdan incelenmektedir. Kan grupları ve COVID-19 ilişkisi de birçok araştırmada tartışılmıştır. Çalışmamızın amacı, COVID-19 hastalarının kan gruplarına göre hemogram parametrelerini incelemektir. Gereç ve Yöntemler: Çalışmamız, retrospektif olarak tasarlanmış, tanımlayıcı-kesitsel bir çalışmadır. Çalışmada, 01.12.2020-01.02.2021 tarihleri arasında COVID-19 şüphesi ile acil pandemi polikliniğine başvuran hastalar kan grupları ve laboratuar tetkikleri ile değerlendirildi. Bulgular: Çalışmaya toplam 527 hasta dahil edildi. Çalışmaya dahil edilen hastaların %31,1’i (n=164) erkek,%68,9’u (n=363) ise kadındı. Çalışmaya dahil edilen hastaların %51,6’sı (n=272) COVID-19 negatif, %48,4’ü (n=255) ise COVID-19 pozitifti. Hastaların COVID-19 tanıları ile kan grupları arasında anlamlı bir farklılık izlenmedi (p=0,799). Hastaların COVID-19 olma durumu ile Rh faktörü arasında anlamlı bir farklılık izlenmedi (p=0,240). COVID-19 pozitif grupta, lenfosit ve CRP değerlerinde anlamlı farklılık izlenmezken (p>0,05); hemoglobin (p=0,028) ve WBC (p=0,014) değerlerinde anlamlı farklılıklar izlendi. Sonuç: Çalışma sonuçlarında ABO kan grubu ve Rh grubu açısından COVID-19 pozitif ve negatif hastalar açısından anlamlı bir fark olmadığı tespit edildi. Bununla birlikte, AB kan grubu olan PZR pozitif hastaların, WBC ve hemoglobin düzeylerinin diğer kan gruplarına göre anlamlı olarak düşüklük tespit edilmiştir. COVID pozitif hastaların kan grupları ile laboratuvar parametrelerinin ilişkisini açıklayabilmek için ileride yapılacak daha geniş kapsamlı araştırmalara ihtiyaç vardır.
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    COVID-19 Pandemisi Öncesi ve Sonrası Alt Ekstremite Venöz Doppler Ultrasonografi Sonuçlarının Değerlendirilmesi; Retrospektif Bir Çalışma
    (Duzce University, 2024) Boğan, Mustafa; Bal, Melih; Gürdal, Tarık; Selki, Kudret; Kaya, Abdulkadir; Kömürcü, Özkan; Altınsoy, Hasan Baki
    Amaç: COVID-19 testi pozitifliği asemptomatik bireyler arasında bildirilmiştir ve asemptomatik kişilerin de tromboembolik olaylar için risk altında olduğu düşünülmektedir. Bu çalışmanın amacı, COVID-19 testinden bağımsız olarak, pandemi öncesi ve sonrasında derin ven trombozu (DVT) ön tanısıyla alt ekstremite Doppler ultrasonografisi (DUS) yapılan hastaların sonuçlarını karşılaştırmaktır. Yöntem: Toplam 35 aylık süre boyunca (01/08/2018 - 01/07/2021) Radyoloji Bölümünde RDUS yapılan hastalar analiz edildi. Çalışma dönemi boyunca toplam 599 hastaya RDUS yapılmıştır. Bulgular: Pandemi sonrasında daha fazla pozitif DVT bulgusu gözlenmiştir (n=43, %18,3, p=0,005) (bu hastaların yalnızca ikisinde pozitif COVID-19 sonucu vardı). Son üç ay içinde hastaneye yatış öyküsü, D-dimer, platelet (PLT), ortalama platelet hacmi (MPV), (lökosit sayısı) WBC, nötrofil sayısı, lenfosit sayısı, nötrofil/ lenfosit oranı (NLR) değerleri, komorbidite ve antiagregan kullanımı farklı değildi (p>0.05). Sonuç: Pandemi sırasında virüse maruz kalan ancak semptom göstermeyen bireyler (özellikle yaşlı bireyler) bile DVT riski altındadır.
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    Cupping Therapy and Scientific Basics
    (2022) Kaya, Abdulkadir; Tasdemır, Lale; Çayır, Yasemin
    Cupping therapy is a traditional and complementary medicine practice that has a history of 5000 years and is used in many societies. One of the 15 complementary medicine methods accepted in the Regulation on Traditional and Complementary Medicine Practices published by the Ministry of Health in Turkey is cupping. In this article, cupping therapy application and studies on cupping therapy will be presented.
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    Effects of the COVID-19 Pandemic on Smoking
    (Duzce Univ, Fac Medicine, 2021) Gamsızkan, Zerrin; Kaya, Abdulkadir; Sungur, Mehmet Ali; Tuncel, Mertcan; Özdemir, Funda; Baştan, Gizem Gül; Çınar, Alpin Derya
    Objective: The aim of this study is to examine the changes in characteristics of smoking habits during the pandemic period. Methods: This study was conducted on the patients who admitted to Duzce University Medical Faculty Smoking Cessation Outpatient Clinic between June 2020 and January 2021 and a control group with similar age, gender, and educational background characteristics. Results: The study group with 165 patients who quit smoking during the pandemic period and the control group with 163 patients were included in the study. It was detected that patients who quit smoking during the pandemic period had attempted to quit smoking significantly less compared to those who continue smoking (p <0.04). The fagerstrom cigarette addiction scale scores of the patients who quit smoking during the pandemic period were found to be significantly lower than the patients who continued to smoke (p <0.001). A significant difference was found between patients who quit smoking during the pandemic period and patients who continued to smoke, in terms of psychological resilience scale total score and all subgroups (p <0.001). Conclusions: The results of our study show that the rate of efforts to quit smoking increased during the pandemic period, because smokers were affected by the negative relationship between COVID-19 and smoking, and more cessation behavior. We suggest that every patient who admitted to health institutions should be questioned in terms of smoking behavior and the psychological resilience of the patients should be evaluated.
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    Evaluation of Knowledge, Attitudes and Behaviors of Physicians Working in a University Hospital About Smoking Cessation Treatment
    (Tıbbi Kayıtlar Derneği, 2024) Ünal, Safa; Kaya, Abdulkadir
    Aim: Tobacco use is a preventable cause of morbidity and mortality and a global public health problem. It is clear that physicians need to increase their awareness, increase their level of knowledge, and change their negative attitudes and behaviours about smoking, which is a risk factor for many preventable diseases in the world. This study was planned to evaluate the knowledge, attitudes and behaviours of physicians working in a university hospital regarding smoking cessation treatments. Material and Method: This study was a descriptive and cross-sectional study. The study included 203 physicians. A printed questionnaire form was used to collect data. Nicotine dependence of the participants who smoked cigarettes was evaluated by Fagerström nicotine dependence test (FNBT). Data were analyzed using SPSS 23.0 statistical package form. A value of p
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    Evaluation of Training Family Health Center Practice in Family Medicine Residency Education
    (Ataturk University, 2024) Bayhan, Nesibe Derya; Kaya, Abdulkadir
    Objective: Tertiary hospitals offer advanced health services, including chronic disease management, whereas primary health care centers focus on services such as pregnancy follow-up, child care, vaccination, and periodic health screenings. These differing roles highlight the need for Education Family Health Centers (EHC), which are increasingly important in family medicine education. This study assesses the perceived necessity of EFHCs among family medicine specialists and residents. Methods: A descriptive cross-sectional survey was conducted among family physicians via Google Forms between February and April 2022. The survey collected sociodemographic data and assessed knowledge related to primary care. Participants’ work status in EFHCs and their performance on knowledge questions were compared. Results: The study included 263 physicians, 58.2% female and 41.8% male. Among them, 62% were married, 55.1% were full-time family medicine residents, 16.3% were contracted residents, and 28.5% were specialists. EFHC training was part of specialty education for 35% of the participants. Additionally, 18.6% had worked in EFHCs, and 15.6% had a responsible trainer. Those who had a responsible trainer in an EFHC scored significantly higher on knowledge questions (P=.049). However, no significant difference was observed in knowledge levels on the basis of the requirements of EFHC or its inclusion in specialty training. Conclusion: This study highlights the necessity of EFHCs and the crucial role of trainers within these centers. The findings suggest that integrating EFHCs into specialty training could enhance educational outcomes and better prepare family medicine residents. These findings reveal that the EASM has an important role in family medicine speciality education and that training increases the quality of education.
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    Fiziksel Tıp ve Rehabilitasyon Polikliniğine Başvuran Hastaların Geleneksel ve Tamamlayıcı Tıp Yöntemlerini Kullanma Durumları: Kesitsel Bir Araştırma
    (2023) Samancı, Rumeysa; Sultanoğlu, Tuba; Kaya, Abdulkadir; Ataoğlu, Sarfinaz
    Amaç: Fiziksel Tıp ve Rehabilitasyon polikliniğine başvuran hastaların geleneksel ve tamamlayıcı tıp (GETAT) uygulamalarını kullanma durumları sorgulamak ve ayrıca ağrı şikayeti veya romatolojik bir hastalığın bu uygulamaları kullanma durumunu etkileyip etkilemeyeceğini araştırmak amaçlandı. Gereç ve Yöntemler: Bu araştırma, Düzce Üniversitesi Tıp Fakültesi Araştırma ve Uygulama Hastanesi, Fiziksel Tıp ve Rehabilitasyon Polikliniğine 2020 yılı Kasım ayı ile 2021 yılı Nisan ayı arasında başvuran ve araştırmaya katılmayı kabul eden 119 hasta ile gerçekleştirildi. Araştırmada veri toplama aracı olarak; literatür taraması sonucunda araştırmacılar tarafından oluşturulan ve toplam 26 sorudan oluşan anket formu yüz yüze görüşme tekniği ile uygulandı. Bulgular: Katılımcıların %63,6’sı herhangi bir GETAT uygulamalarını duymuştu ve %17,8’i de bu uygulamalarından en az birini yaptırmıştı. GETAT uygulamalarını duyan katılımcılar arasında en çok duyulan GETAT uygulamaları akupuntur (%74,7), hiruidoterapi (%73,3) ve kupa terapi (%62,7) iken GETAT uygulamalarını yaptıran katılımcılar arasında en çok yaptırılan GETAT uygulamaları ise kupa terapi (%71,4), hiruidoterapi (%23,8), fitoterapi (%19) idi. Katılımcıların cinsiyet, ekonomik durum, çalışma durumu, eğitim durumu, medeni durum, ağrı şikayeti ve süresi, kronik hastalık, romatizmal hastalıklar ile GETAT yöntemlerini kullanma durumlarının ilişkisi incelendiğinde sadece kronik hastalık ve fibromiyalji ile GETAT yöntemlerini kullanma durumları arasında istatistiksel olarak anlamlı bir fark bulunmuştur (p
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    Hisse Senedi Fiyatları ile Makroekonomik Değişkenlerin Etkileşimi
    (Dokuz Eylül Üniversitesi, 2011) Özer, Ali; Kaya, Abdulkadir; Özer, NEvin
    Bu çalışmanın amacı, Ocak 1996- Aralık 2009 dönemi aylık verileri kullanılarak, İMKB 100 Endeksi ile bazı makroekonomik değişkenler arasında bir ilişki olup olmadığını tespit etmektir. Bağımlı değişken olarak İMKB-100 Endeksi, bağımsız değişkenler olarak da Faiz Oranı, Para Arzı, Dış Ticaret Dengesi, Sanayi Üretim Endeksi, Altın Fiyatları, Döviz Kuru ve Tüketici Fiyat Endeksi kullanılmıştır. Çalışma En Küçük Kareler Tahmin Yöntemi, Johansen-Juselius Eşbütünleşme Testi, Granger Nedensellik Testi ve VEC modelleri uygulanmıştır. Çalışmadan elde edilen sonuçlara göre, hisse senedi fiyatı ile bazı makro ekonomik değişkenler arasında uzun dönemli anlamlı bir ilişki bulunmaktadır.
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    Hypnosis and Anesthesia
    (Düzce Üniversitesi, 2020) Avşar, Murat Tolga; Okudan, Resmiye Nur; Kaya, Abdulkadir
    Hypnosis is the acceptance of a suggestion. Perception, memory, and voluntary movements can be changed with hypnotherapy. Rather than being an alternative to general or regional anesthesia in the field of anesthesia, hypnosis should be used as a complementary method that is integrated with these methods, increases the patient's compliance and comfort, and accelerates the healing process. Hypnosis is an important application in the reduction and control of both acute and chronic pain. In this text, we analyze the subject of hypnoanesthesia and discuss studies on hypnoanesthesia.
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    The Increasing Importance of the e-Health System after the COVID-19 Outbreak with New Healthcare Expectations
    (2021) Gamsızkan, Zerrin; Kaya, Abdulkadir; Sungur, Mehmet Ali
    Aim: The health system is undergoing a rapid transformation with the constantly developing world. The Covid-19 pandemic that threatens humanity seems to change the health system as in every field. The study aimed to determine the use of the e-Health system before and after the pandemic and how health services have changed after the pandemic. Methods: The study was designed with a mixed method that includes analysis of qualitative and quantitative data. The quantitative data of the study were collected with the help of a questionnaire before the pandemic. Qualitative data acquisition and analysis were carried out after the pandemic. Results: According to the results of the study, the rate of participants who did not use the e-Health system before the pandemic was 73.5% (n=155). When asked about the reasons for not using the eHealth system; 43.2% of the participants (n=67) stated that they did not need it, 28.4% (n=44) were not aware of the system and 28.4% (n=44) stated that they did not know how to use the system. According to the qualitative data results, five main themes were obtained after the Covid -19 outbreak. The themes were; getting health information and guidance remotely during the pandemic is the best alternative, creating a sense of trust, compliance with the new situation, expectations from the health system in the new period, and expectations for guidance in accessing e-health information. Conclusion: The most important result of this study, the increase in the use of distance health and ehealth, seems to be the framework of the new health service. When the results are read in this context, it can be predicted that a large share of the investments in the field of health will be shifted to digital health systems.
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    Investigation of incidental findings of temporomandibular joint disorders on brain magnetic resonance imaging in three-dimensional T2-weighted SPACE sequence performed for brain imaging
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2024) Samancı, Rümeysa; Ogul, Hayri; Gökce, Ayşe; Kaya, Abdulkadir; Ataoglu, Safinaz
    Objectives: The study aimed to determine the temporomandibular joint (TMJ) findings, to investigate the prevalence contribution of this sequence on cases in which cranial magnetic resonance examination was performed and three-dimensional (3D) T2-SPACE (T2-weighted sampling perfection with application-optimized contrasts using different flip-angle evolutions) sequence was used by retrospectively scanning the magnetic resonance imaging (MRI) archive of our hospital, and to reveal the advantages of the 3D-T2 SPACE sequence in patients with TMJ disorders. Patients and methods: The cross-sectional retrospective study was conducted with 499 patients (289 females, 210 males; mean age: 50.1 +/- 17.7 years; range, 8 to 92 years) who underwent brain MRI and had 3D-T2 SPACE between March 1, 2021 and March 1, 2022. Two radiologists analyzed the TMJs of the subjects included in the study in 3D-T2 SPACE sequences. Results: At least one incidental finding was detected in the TMJ in 37.1% (n=185) of the patients included in our study. In our study, the most common (13.6%) MRI findings were osteoarthritic changes and synovial cysts. Joint effusion (13.2%) and disc displacement (9%) were less frequent. When the relationship between the age of the patients and the presence of incidental findings, degeneration, effusion, disc displacement, and cyst was examined, the age of the patients with incidental findings (p=0.001) and osteoarthritic changes (p<0.001) was statistically significantly higher. Conclusion: Incidental findings, particularly osteoarthritic changes and synovial cysts, can be seen quite commonly in the TMJ in brain MRI using 3D T2-SPACE sequences in the general population. The 3D T2-SPACE sequence provides valuable information in the recognition of TMJ disorders.
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    Leech Therapy In A Case With Arterial Embolism
    (Düzce Üniversitesi, 2020) Sarı, Tarık; Kaya, Abdulkadir
    Although there have been significant advances in the treatment of cardiovascular diseases, acute peripheral arterial blockage is still important due to limb-threatening ischemia and loss of function it causes in vital organs. Leeches have been used in the treatment of certain diseases since ancient times. US Food and Drug Administration (FDA) permitted the sale of leeches in this country and their use for general purposes, plastic surgery and micro-surgery in 2004. There are studies in the literature reporting leech therapy administration in post-surgical vascular permeability complications. In conclusion, huridotherapy can be used as an alternative treatment in addition to medical treatment of arterial embolism. This article studied a case that had peripheral arterial embolism and recovered through leech treatment.
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    The predictive role of laboratory parameters in cardiovascular risk assessment in obese
    (Lippincott Williams & Wilkins, 2023) Kaya, Abdulkadir; Gamsizkan, Zerrin; Kaya, Nursel; Davran, Fatih
    The significance of cardiovascular diseases in mortality is indisputable. It is well-established that cardiovascular diseases are more prevalent among individuals with obesity. This study aimed to determine the predictive value of easily accessible hematological and biochemical parameters in assessing cardiovascular risk among obese patients. The study was designed as an observational retrospective. Department of Family Medicine, study was carried out between 25/06/2022 to 30/10/2022. The data of 439 obese patients were analyzed retrospectively. Using the online Heart Score system, the patients were classified into low, medium, high, and very high cardiovascular risk categories. The hemogram and certain biochemistry values of the patients at the time of admission were examined. Receiver operating characteristic (ROC) analyses were conducted to discriminate cardiovascular risk classes based on laboratory values. Markers with high diagnostic value, including a high area under the curve (AUC) value, sensitivity, and specificity, were presented. Significant differences were observed between the groups in terms of age, systolic blood pressure, diastolic blood pressure, total cholesterol, low-density lipoprotein, glucose, HbA1c, hemoglobin, platelet count, neutrophil (NEU) count, and platelet-lymphocyte ratio parameters (P < .05). The white blood cell count and NEU count of patients in the high-risk groups were found to have significantly higher AUC values compared to the moderate-risk group (AUC values of .737 and .779, respectively). The white blood cell and NEU parameters were found to have a positive predictive value in estimating the degree of cardiovascular risk. These parameters can potentially serve as biomarkers in identifying individuals at high risks for cardiovascular diseases.
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    Significance of laboratory parameters in diagnosing acute appendicitis during pregnancy
    (Wiley, 2022) Peksöz, Rıfat; Dişçi, Esra; Kaya, Abdulkadir; Ağırman, Enes; Korkut, Ercan; Aksungur, Nurhak; Altundaş, Necip
    Background Acute appendicitis (AA) is the most frequently seen surgical emergency in pregnant women and the most frequently encountered cause of non-obstetric acute abdomen. Due to the physiological and anatomical changes that occur during pregnancy and the limited use of radiological methods, it is difficult to diagnose AA during pregnancy. These conditions increase the risk of morbidity and mortality; therefore, it is crucial to identify ideal laboratory markers that can be utilized to diagnose disease. Methods One hundred and ten pregnancies that fulfilled the inclusion criteria for AA diagnosis were retrospectively analysed between 2010 and 2021. Markers with high diagnostic values were discussed. Results The patients were divided into three groups as follows; Group I: negative appendectomy (n = 19); Group IIa: uncomplicated appendicitis (n = 59); Group IIb: complicated appendicitis (n = 32). There was no statistically significant difference in mean age or gestational week (P > 0.05). Group IIb had a higher rate of complications and a longer length of hospital stay (P < 0.05). There were significant differences between the groups in terms of white blood cell (WBC), neutrophil, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein, lymphocyte-to- C-reactive protein ratio, total, direct, and indirect bilirubin values (P < 0.05). While platelet and lactate dehydrogenase (LDH) values did not differ substantially between groups, both were found to have a high diagnostic value. Conclusion It was concluded that WBC, neutrophil, NLR, PLR, total, direct and indirect bilirubin levels could be utilized to diagnose AA. Moreover, levels of WBC, neutrophil, NLR, platelet, PLR, LDH, total, direct and indirect bilirubin can be utilized to diagnose complicated appendicitis.
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