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    Clinical and Magnetic Resonance Imaging Findings of Patients with Acute Carbon Monoxide Poisoning
    (2020) Kavaka, Nezih; Sultanoğlu, Hasan; Kavak, Rasime Pelin; Özdemir, Meltem
    Objective: We aim to evaluate the demographic and clinical characteristics of patients withacute carbon monoxide (CO) poisoning, who had a Glasgow Coma Score (GCS) below 15,and who had cerebral lesions detected in magnetic resonance imaging (MRI).Methods: The age, gender, causes of CO intoxication, clinical signs, neurological findings,GCS, blood carboxyhemoglobin level (COHb), serum pH, lactate, creatine kinase (CK),creatinine kinase-myocardial band MB (CK-MB), troponin-I level, brain MRI (T1-weighted, T2-weighted, FLAIR and diffusion-weighted imaging), treatment, and mortalitystatus of 327 patients were evaluated retrospectively.Results: The median age of patients was 31.5 years (IQR=19.5 years), 72.2% of the patientswere women. Neurological findings were detected in 34 (10.4%) of the patients. Thefrequency of dyspnea was significantly higher in patients with neurological findings(p<0.05). The COHb and lactate levels of patients with neurological findings were found tobe significantly high, the pH level was significantly lower (p<0.05). There was nosignificant relationship between the presence of neurological findings and CK, CK-MB, andtroponin-I levels (p>0.05). Patients with neurological findings were found to have asignificantly longer follow-up period, more frequently received hyperbaric oxygen therapy(p<0.05). The rate of hospitalization was 10.7%, the mortality rate was 0.9%.Hospitalization and mortality rates were significantly high in patients with neurologicalfindings (p <0.05). Pathological findings were detected in 13 (40.6%) of 32 of patients(except for 2 patients who did not respond to the resuscitation) who had an MRI.Conclusions: It was determined that acute CO poisoning may lead to acute brain damage,40.6% would be detected in brain MRIs taken in patients during the acute phase.