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  • Küçük Resim
    Öğe
    Detection of cisplatin-induced ototoxicity with transient evoked otoacoustic emission test before pure tone audiometer
    (Springer, 2010) Yılmaz, Süleyman; Öktem, Fatih; Karaman, Emin
    Our aim was to investigate cisplatin ototoxicity with transient evoked otoacoustic emission (TEOAE) test before it is seen with pure tone audiometer. In our study, we compared the hearing of the patients who are receiving 100 mg/m(2) 4-cycle cisplatin for lung cancer, with pure tone audiometer and transient evoked otoacoustic emission test in 1,000, 2,000 and 4,000 Hz. We found 55% hearing decrease with pure tone audiometer in patients that are receiving 100 mg/m(2) 4-cycle cisplatin for lung cancer. We also established emission amplitude decrease with TEOAE test in 85% of the patients. When we compare the patients' pure tone audiometer in 1,000, 2,000 and 4,000 Hz and TEOAE amplitude changes we did not find statistically significant results (P > 0.05), but when we compare the patients' TEOAE amplitude changes in 1,000, 2,000 and 4,000 Hz with control group we found statistically significant results (P < 0.05). Our results show that cisplatin ototoxicity could be find out with TEOAE test before it is seen with pure tone audiometer.
  • Küçük Resim
    Öğe
    Effects of sevoflurane and TIVA with propofol on middle ear pressure
    (Elsevier Ireland Ltd, 2006) Öztürk, Özcan; Demiraran, Yavuz; İlçe, Zekeriya; Akbay, Buket Kocaman; Güçlü, Ender; Karaman, Emin
    Objective: To evaluate the effects of sevoflurane and TIVA with propofol on middle ear pressure and to show the importance of anesthesia without using any inhalational agents during middle ear surgery. Study design: A prospective, randomized controlled clinical study. Methods: In this study, 25 male children that were scheduled for circumcision were randomised into two groups. Group I (n = 13) received TIVA with propofol and group II (n = 12) received sevoflurane. Baseline tympanometry reading was performed on each ear just before anesthesia. The next tympanometry reading was taken 10 min after applying the laryngeal mask. Data were analysed by Mann-Whitney U (between groups) and Wilcoxon tests (within groups). Results: Mean MEP values in 26 ears of 13 boys in group I did not show any significant difference before and after the anesthesia with propofol (p > 0.05). In group II mean MEP values in 24 ears of 12 boys showed a significant increase after the anesthesia with sevoflurane (p < 0.001). No significant difference was found between the MEP values of the two groups before the anesthesia (p > 0.05), and MEP values measured during the anesthesia were significantly higher in group II (p = 0.007). Conclusion: Sevoflurane may increase the middle ear pressure and TIVA with propofol may be used in middle ear operations more safely than sevoflurane. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
  • Küçük Resim
    Öğe
    Tip 1 timpanoplasti sonuçlarımız
    (2009) Yılmaz, Süleyman; Karaman, Emin; Güçlü, Ender; Yaman, Hüseyin; Akkan, Nermin
    Amaç: Kronik otitis media cerrahisindeki uygulamalarımızdan tip 1 timpanoplastideki başarılarımızın ve başarısızlıklarımızın nedenlerinin araştırılmasıdır. Gereç ve Yöntemler: 2000 ile 2005 yılları arasında kronik otitis media nedeniyle tip 1 timpanoplasti yapılan 68 hasta retrospektif olarak incelendi. Hastaların cinsiyetleri, ameliyat sırasındaki yaşları, kulak zarı perforasyon tipleri (santral, marjinal, subtotal ve total), ameliyat tekniği (overlay, underlay), ameliyat öncesi ve sonrası saf ses odiolojik değerlendirmeleri (500-1000-2000-4000Hz) tespit edildi. İstatistiksel değerlendirmeler Student t test ve Mann-Whitney U testi kullanılarak yapıldı. Bulgular: Çalışmamızda cinsiyet, operasyon yaşı, perforasyon tipi (santral, marjinal, subtotal, total) ve ameliyat tekniği (overlay, underlay) ile timpanoplasti sonrası zarın intaktlığı arasında istatistiksel olarak anlamlı bir ilişki saptanmadı (p0.05). Timpanoplasti sonrası odiogram değerlerimize baktığımızda tip 1 timpanoplastide postoperatif gap kazanç ortalamamızı 8.3 db olarak bulduk. Sonuç: Retrospektif olarak yaptığımız bu çalışmanın sonucunda tip 1 timpanoplasti başarısının yaş, cinsiyet, perforasyon yeri ve ameliyat tekniği (overlay, underlay) gibi faktörlerden etkilenmediğini saptadık. Postoperatif işitme kazancında ise dramatik iyileşmeler saptamasak ta kabul edilebilir sonuçlar alınabileceğini düşünüyoruz.