Yazar "Karadağ, Mehmet" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Acil Pandemi Polikliniğine Başvuran ve COVID-19 Şüphesiyle Değerlendirilen Hastaların Retrospektif Analizi(2021) Altınsoy, Hasan Baki; Naldemir, İbrahim Feyyaz; Çalışkan, Emel; Şahin, İbrahim Ethem; Karadağ, Mehmet; Boğan, MustafaAmaç: SARS-CoV-2 olarak adlandırılan yeni tip korona virüsün neden olduğu COVID-19 pandemisi halen tüm dünyada etkisini sürdürmektedir. COVID-19 etkeninin neden olduğu semptomlar diğer solunum yolu etkenlerine benzese de toplumsal etkileri oldukça şiddetli ve farklı seyretmektedir. Bu çalışma hastanemizin acil servis girişinde oluşturulan acil pandemi polikliniğine başvuran ve COVID-19 ön tanısıyla tetkik edilen hastaların analizinin yapılması amacıyla planlanmıştır.Gereç ve Yöntemler: Acil pandemi polikliniğine başvurmuş 16 yaş ve üzeri hastalardan, ateş, öksürük, nefes darlığı şikayetleri olup COVID-19 şüphesiyle polimeraz zincir reaksiyonu (PZR) testi için üst solunum yolundan sürüntü örneği alınmış ve Toraks bilgisayarlı tomografisi (TBT) yapılmış olanlar dahil edilmiştir. Bulgular: PZR testi pozitif ve negatif olan hastaların geliş şikayetleri karşılaştırıldığında, iki grubun da benzer şikayetlere sahip olduğu görülmüştür. PZR testi pozitif hastaların WBC sayıları (5748,39 ± 1547,01), nötrofil sayıları (3650,32 ± 1355,58), lenfosit sayıları (1467,74 ± 472,3) ve platelet sayıları (224,65 ± 76,01); PZR testi negatif olan hastalardan daha düşük bulunmuştur.Sonuç: COVID-19 PZR testi pozitif hastalarda daha düşük WBC, nötrofil ve lenfosit sayısı tespit edilmiştir. Toraks bilgisayarlı tomografi bulguları olan PZR pozitif vakalarda platelet sayısı daha düşük ve CRP değeri daha yüksek izlenmiştir. Bu verilerin özellikle ileri tanı testlerinin olmadığı veya geç sonuçlandığı sağlık kuruluşları için hastalıktan şüphelenme ve erken izolasyon için yol gösterici olabileceğini düşünmekteyiz.Öğe Analysis of publications related to Triage in the Web of Science database(2022) Karadağ, Mehmet; Boğan, MustafaObjective The aim of this study is to make a bibliometric analysis of the publications made about the increasing triage in recent years. Materials and Methods The review of the articles to be included in this study was conducted on June 8, 2021 using the database of Web of Science Core Collection. Triage was written in the subject section and a search was made in the form. “Web of Science Categories: (All); Document Types: (All); Languages: (English); Timespan: (All); Indexes: (All)”. During the search, no restrictions were entered regarding the dates of the publications. The data were transferred to VOSviewer software and analyzed systematically. Results A total of 22653 publications were descripted between 1980 and 2021. It was found that the most publications were made in the field of emergency medicine (EM) (n=3798; 16,76%). It has been observed that the most publications have been made from the United States. (n=10049; 44,36%). When Turkey's place in all fields and EM is examined; it was seen that it was in the 26th rank (n=225; 0,99%) in the all fields, and 18th in the EM field (n=50; 1,32%). Conclusion Studies and publications on triage have been conducted most often in the field of emergency medicine. However, Turkey's place in the current literature is far behind compared to the risks it poses. It is recommended to increase the work on this area in our country.Öğe Comparison of GAM and DLNM Methods for Disease Modeling in Environmental Epidemiology(2021) Al, Behçet; Kul, Seval; Yoloğlu, Saim; Boğan, Mustafa; Karadağ, MehmetABSTRACT Objective: In this study, it was aimed to compare the performance results of the methods modeled by using generalized additive models (GAM) and distributed lag non-linear models (DLNM) methods from real data of three different outcome variables of three separate diseases related to air pollution. Material and Methods: The data were retrospectively obtained from three hospitals under the General Secretariat of Gaziantep province public hospitals for a total of 1,916 days between 01 January 2009 and 31 March 2014. Response variables were number of the emergency unit admission, hospitalization and mortality due to asthma, chronic obstructive pulmonary disease (COPD) and pneumonia. The response variables were estimated by GAM and DLNM methods by building four different models and the performances of the models were compared. Results: When the estimation performances of GAM and DLNM methods are compared for each of the dependent variables in the prediction of hospitalizations due to asthma, GAM model IV [Akaike Information Criteria (AIC) (4,280.63)] values were found to perform the best. It was observed that DLNM method performed better than GAM in models established for the prediction of almost all other dependent variables. For when compare the odds ratio (OR) plot estimated on particulate matter (PM10); it was seen that GAM method made predictions with lower standard error compared to DLNM methods. Conclusion: When the models created with each dependent variable were compared; it was generally observed that superior performance was obtained from the DLNM method. However, the lowest standard error in the OR charts were observed in the models using the GAM method.Öğe Novel inflammatory targets for immunotherapies in pediatric patients with trichotillomania(Elsevier GmbH, 2020) Kütük, Meryem Özlem; Tufan, Ali Evren; Kılıçaslan, Fethiye; Mutluer, Tuba; Gökçen, Cem; Karadağ, Mehmet; Kütük, ÖzgürImmune dysregulation may be important in the etiology of obsessive-compulsive and related disordersandbody-focusedrepetitivebehaviors, such as Trichotillomania (TTM). The role of inflammation and inflammatory markers in TTM has received relatively little attention. This study was aimed to determine the expression levels of inflammatory markers (i.e. IL-1?, IL-1?, IL-4, IL-6, IL-17, TNF-? and TGF-?) in peripheral blood mononuclear cells of children with TTM and healthy controls and to evaluate their association with clinical variables. Seventy-seven patients with TTM and 107 healthy controls were enrolled in the study. Peripheral blood was collected in standardized conditions. The mean age of patients and controls did not differ significantly (10.8 ± 4.4 and 12.0 ± 3.2 years; respectively). The majority of patients with TTM and controls were females (n = 55, 71.4 % and n = 55, 51.4 %; respectively); with a greater preponderance of females among TTM. Patients with TTM had significantly elevated expression levels of TNF-?, IL-6 and IL-17 compared to controls. However, the expression level of IL-4 was significantly reduced in TTM patients compared to controls. Accordingly, we found a pro-inflammatory state in TTM and those findings may suggest novel treatment options for TTM and further, cross-disciplinary studies focusing on neuro- inflammation in TTM conducted on larger samples are needed. © 2020 Elsevier GmbH
