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    Fetal nuchal translucency: is there an association with birthweight and neonatal wellbeing?
    (Galenos Yayincilik, 2019) Kalem, Ziya; Kaya, Aşkı Ellibeş; Bakırarar, Batuhan; Kalem, Müberra Namlı
    Objective: To evaluate the relationship between nuchal translucency (NT) values with birthweight and the wellbeing of the newborn. Materials and Methods: This retrospective cohort study that included 508 patients made use of data on healthy full-term, singleton, live birth newborns in a university hospital between 2016 and 2018. The relationship between the NT multiple of the median (MoM) value and maternal body mass index, birthweight, sex, need for neonatal intensive care unit (NICU), and APGAR scores was evaluated. Similarly, the relationship between birthweight and NT MoM, and biochemical data in the first trimester was also evaluated. Results: There was a positive correlation between NT and birthweight (p<0.001). The need for NICU admission increased (p=0.001), and APGAR 1st minute scores decreased (p=0.001) with increasing NT, and APGAR 5th minute scores remained unchanged (p=0.057). Conclusion: The present study identified a positive correlation between first trimester NT and birthweight, and a negative correlation with the wellbeing of the neonate.
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    An Optimal Uterine Closure Technique for Better Scar Healing and Avoiding Isthmocele in Cesarean Section: A Randomized Controlled Study
    (Taylor & Francis Inc, 2019) Kalem, Ziya; Kaya, Aşkı Ellibeş; Bakırarar, Batuhan; Başbuğ, Alper; Kalem, Müberra Namlı
    Objective: The aim of this study is to compare the effects of two different uterine closure techniques, used during cesarean section (CS) operations on isthmocele formation. Material and Methods: This prospective, randomized, controlled study was performed on 138 patients in a university hospital between the dates December 2016 and August 2017. Uterine closures were performed using the double-layer, far-far-near-near (FFNN) unlocked technique, in the study group (n = 70) and using a single-layer continuous locked (SLL) technique in the control group (n = 68). The presence of isthmocele, residual myometrial thickness (RMT), postmenstrual spotting, dysmenorrhea, chronic pelvic pain and uterus position were evaluated in postoperative sixth month. Results: Isthmocele formation was less frequent and RMT was greater in the study group when compared to the control group (p < 0.001 and p < 0.001, respectively). Duration of operation, amount of blood loss and additional hemostatic suture requirement were not significantly different between the two groups (p = 0.221, p = 0.520 and p = 0.930, respectively). Postmenstrual spotting was less common in FFNN group, while the rates of chronic pelvic pain and dysmenorrhea were not significantly different between the groups (p = 0.002, p = 0.205 and p = 0.490, respectively). Conclusion: The findings of the present study demonstrate that uterine closure using the FFNN technique is beneficial in terms of providing protection from isthmocele formation and ensuring sufficient RMT. This method has the potential to become the optimal uterine closure technique, but the findings of the present study should be supported by large-scale studies in the future.
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    The relationship between the levels of anti-Mullerian hormone, vaspin, visfatin, and the patterns of nutrition and menstruation in non-polycystic ovary syndrome and non-obese young women
    (7847050 Canada Inc, 2019) Kalem, Ziya; Kalem, Müberra Namlı; Akgün, Nilüfer; Kaya, Aşkı Ellibeş; Bakırarar, Batuhan; Aydın, S.
    Purpose of Investigation: The aim of this study was to investigate the relationship between the levels of anti-Mullerian hormone (AMH), vaspin, visfatin, and the patterns of nutrition and menstruation in healthy non-polycystic ovary syndrome (PCOS) and non-obese young women. Materials and Methods: A total of 77 medical faculty students aged between 18 and 28 years were included in the study. Blood levels of AMH, vaspin, and visfatin of individuals were examined by the enzyme-linked immunosorbent assay (ELISA) method. Results: There was no statistically significant relationship between the AMH vaspin, and visfatin (p = 0.712), a statistically significant positive correlation was found between the vaspin and visfatin (p <0,001), There was no relationship of AMH, vaspin, and visfatin with age, body mass index (BNI), and anthropometric body measurements. The levels of vaspin and visfatin increased (P < 0.001 and p < 0.001, respectively), as the nutritional quality decreased, in the group with regular exercise. The AMH levels were lower in the smokers and also in the group with irregular menstrual cycle (p = 0.048 and p = 0.001, respectively). Conclusion: Based on the present study results, the authors conclude that there is an interactive relation among the reproductive system, adipose tissue, and daily life habits of young individuals.