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Öğe Evaluation of Nasal Mucociliary Clearance in Recently Diagnosed Covid-19 Patients Before Treatment(Duzce Univ, Fac Medicine, 2023) Koder, Ahmet; Kilicaslan, Saffet; Belada, Abdullah; Habiloglu, Arif Dogan; Ataoglu, Ozlem; Sungur, Mehmet Ali; Atik, DursunObjective: Our study aims to evaluate the nasal mucociliary clearance (NMC) in Covid-19 patients who have been recently diagnosed and not been treated yet and investigate how Covid-19 affects NMC.Methods: A total of 120 participants, who applied to Duzce Ataturk State Hospital between September and November 2020, were included in our study. 60 of them were the participants, diagnosed with Covid-19. And 60 of them were the control group. The age range was 18 to 66. 60 participants, diagnosed with Covid-19 and not yet treated, were included in our study. Those with taste disorders were excluded from the study. The control group consisted of 60 healthy volunteers. NMC was evaluated using a saccharin test. The results were compared in the Statistical Package for Social Sciences (SPSS).Results: The study group, which consisted of 60 Covid-19 participants of whom treatment was not yet started, and the 60-participant healthy control group were evaluated in our study. The average age of the study group was 40,72 +/- 12,96 and 39,16 in the control group. The average NMC was 15,95 +/- 3,37 in the study group, and 8,38 +/- 1,03 in the control group. When evaluated statistically, it was found higher in the study group (p<0,001).Conclusions: NMC acts as a barrier for inhaled foreign bodies. It is a non-specific protection system against airborne pathogens. Consequently, NMC extends in Covid-19 patients.Öğe Identification of Sars-Cov-2 related volatile organic compounds from face masks(Elsevier, 2024) Canbay, Hale Secilmis; Kismali, Gorkem; Emen, Fatih Mehmet; Habiloglu, Arif Dogan; Sareyyupoglu, Baris; Akcay, Aytac; Ozturk, HakanThis study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical sig-nificance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.