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Öğe The 2D and 3D MR arthrographic description of aponeurotic expansion of supraspinatus tendon and biceps tendon anomaly in a large patient cohort(Springer, 2024) Guclu, Derya; Ogul, Hayri; Unlu, Elif Nisa; Tuncer, Kutsi; Kose, Mehmet; Kantarci, Mecit; Eren, SuatObjectiveTo describe the aponeurotic expansion of supraspinatus tendon (AEST) and biceps tendon abnormalities with magnetic resonance (MR) arthrographic examinations and determine their prevalence in patients, we performed a high-resolution 3D direct MR arthrography.Materials and methodsThis was a retrospective study of 700 shoulder MR arthrograms performed between May 2010 and January 2022. Extension in the coronal plane of an AEST on 3D fat-suppressed T1-weighted volumetric interpolated breath-hold examination (VIBE) MR arthrography was identified. Based on its morphology, the AEST on MR arthrography was divided into four subtypes: absence of tendinous thickness in the bicipital synovial surface or intra-synovial tendon-like structure in the bicipital groove, thin and flat tendinous thickness & GE;1 mm of bicipital synovium, oval tendinous structure less than half the size of the adjacent biceps tendon, oval tendinous structure more than half the size of the adjacent biceps tendon, and oval tendinous structure larger than the adjacent biceps tendon. Based on its origin and termination, aponeurotic expansions can be divided into three subtypes: proximal pulley zone, middle humeral neck zone, and distal myotendinous junction zone. Association with the biceps synovium of the AEST was categorized into three types: intra-synovial, extra-synovial, and trans-synovial.ResultsAn AEST in the anterior shoulder joint in 3D VIBE MR arthrography images was identified in 63 (9%) of 700 arthrograms. The most common arthrographic type of AEST was type 1-this was detected in 39 of 63 patients. The most common course type of the AEST was anteriorly midline. The most common distal insertion type was at the tenosynovial sheath of the long head of the biceps tendon (LHBT) in the middle humeral neck zone-this was detected in 31 of 63 patients. There were only 10 MR arthrograms biceps tendon abnormality, including 4 biceps agenesis and 6 split ruptures.ConclusionA 2D and high-resolution 3D MR arthrography can demonstrate the anatomical detail around the bicipital groove and facilitate the differentiation between a biceps tendon anomaly and an AEST. On high-resolution 3D MR arthrographic images, the AEST tends to be in the anterior midline and anteromedial portions of the biceps synovium with intra-synovial, extra-synovial, and trans-synovial courses and its three different insertion types.Öğe The 2D and 3D MR arthrographic description of aponeurotic expansion of supraspinatus tendon and biceps tendon anomaly in a large patient cohort (Jul, 10.1007/s00256-023-04409-1, 2023)(Springer, 2024) Guclu, Derya; Ogul, Hayri; Unlu, Elif Nisa; Tuncer, Kutsi; Kose, Mehmet; Kantarci, Mecit; Eren, Suat[No abstract available]Öğe Assessment of the Effect of Psoriasis and Methotrexate Treatment on Liver Stiffness by ARFI Imaging(Duzce Univ, Fac Medicine, 2023) Guclu, Derya; Karagun, Ebru; Unlu, Elif Nisa; Oktay, Mehtap; Pasin, OzgeObjective: To investigate whether psoriasis and methotrexate used in its treatment cause liver fibrosis and eventually to evaluate the safety of methotrexate in treatment.Methods: 44 cases were included in the study. Methotrexate-using (group 1, n=14) and methotrexate-not-using (group 2, n=13) psoriasis patients were compared retrospectively with a healthy control group (group 3, n=17) according to mean shear wave rates obtainedResults: Mean shear wave velocities were calculated as 2.57 & PLUSMN; 1.13 m/sec in the patients using methotrexate, 2.31 & PLUSMN; 1.16 m/sec in the patients who did not use methotrexate, and 1.56 & PLUSMN; 0.62 m/sec in the healthy control group. While the average shear wave velocity of the 3rd group was found to be significantly lower than that of the 1st and 2nd groups (p=0.032; p=0.012), no significant difference was observed between the 1st and 2nd groups (p=0.755).Conclusions: Shear wave imaging with ARFI quantification findings revealed no evidence that methotrexate therapy is associated with liver fibrosis in psoriasis patients and we think that the increase in liver tissue stiffness in patients using methotrexate for psoriasis is secondary to the inflammatory process caused by psoriasis itself rather than methotrexate.Öğe Comparison of conventional MR arthrography and 3D volumetric MR arthrography in detection of cartilage defects accompanying glenoid labrum pathologies(Springer, 2024) Gokce, Ayse; Guclu, Derya; Unlu, Elif Nisa; Kazoglu, Ibrahim; Arican, Mehmet; Ogul, HayriObjectivesIn this study, we aimed to compare conventional and T1-weighted volumetric magnetic resonance arthrography (MRA) in the diagnosis and grading of glenoid cartilage defects that accompany labral pathologies.Materials and methodsA total of 79 patients who were prediagnosed with labrum pathologies based on shoulder magnetic resonance imaging (MRI) had MRA and CTA between December 2021 and May 2022. CTA was regarded as reference standard. CTA images were examined by a radiologist experienced in musculoskeletal radiology, and MRA images were examined by two radiologists independently to determine presence, grade, and localization of any glenoid cartilage defect, if present. Sensitivity, specificity, and accuracy were calculated separately for conventional and T1-weighted volumetric MRA. In addition, at the last stage, two observers examined all MRAs together, and the presence of a cartilage defect was decided by consensus, and the overall sensitivity, specificity, and accuracy were calculated.ResultsCartilage defect was detected on CTAs of 48 (60.75%) cases of among 79 patients with labrum pathology. The sensitivity, specificity, and accuracy of conventional MRA for two examiners were 17-19%, 100-100%, and 49-51%, respectively, while those values were 67-65%, 92-97%, and 84-77%, respectively, for T1-weighted volumetric MRA. Inter-examiner agreement was excellent for diagnosis of cartilage defects on all MRAs. The overall sensitivity, specificity, and accuracy for detection of glenoid cartilage lesions by MRA were 69%, 97%, and 80%, respectively.ConclusionT1-weighted volumetric MRA seems to demonstrate cartilage defects accompanied with labrum pathologies accurately with high sensitivity, specificity, and excellent inter-examiner agreement.Öğe The Demographic Analysis of the Probable COVID-19 Cases in Terms of RT-PCR Results and Age(Clin Lab Publ, 2021) Akpinar, Guleser; Demir, Mehmet C.; Sultanoglu, Hasan; Sonmez, Feruza T.; Karaman, Kivanc; Keskin, Banu H.; Guclu, DeryaBackground: Despite global prevention and quarantine efforts, the incidence of COVID-19 disease continues to increase. As a possible cause, our aim was to investigate which parameters increase the sensitivity or protection against COVID-19 between RT-PCR positive and RT-PCR negative cases in patients admitted to the emergency department. Methods: In the pandemic process, patients admitted to the hospital with suspicion of COVID-19 were evaluated retrospectively. RT-PCR test was divided into + (for Group 1) and - (Group 2). The gender, age, clinical information, application symptoms, and comorbidity data of the patients were evaluated. Results: One hundred and sixty-seven cases were evaluated in the study. Group 1: 88 cases, M/F ratio: 46/42 and average age 48 +/- 17.3 years, Group 2: 79 cases, M/F ratio was approximately 3/2, and the average age was 48.3 +/- 19.4 years. When the groups were compared in terms of symptoms, fever, cough, weakness, and headache were prominent in Group 1, whereas the contact was significantly higher in Group 2 (p < 0.05). Among the comorbid diseases, only COPD showed a significant difference between the groups, and it was found significantly higher in Group 2 (p < 0.05). Conclusions: Cough, headache, and fever were found valuable in the detection of cases. Attention should be paid to contact isolation to circumvent the pandemic process with less damage. Having chronic diseases, especially COPD, increases the risk of infection with SARS-CoV-2. Close monitoring and control of chronic diseases can positively change the course of COVID-19.Öğe Duzce University Faculty of Medicine Radiology Department in the COVID-19 Pandemic Process(Duzce Univ, 2020) Guclu, Derya; Unlu, Elif NisaRadiology plays an important role in the COVID-19 pandemic outbreak. Besides its role in the diagnosis and follow-up of COVID-19, it undertakes important tasks both in the protection of healthcare workers and in avoiding a potential cause of spread. The aim of the present study is to share our experience and approach during the pandemic and to contribute to the management of other probable pandemic processes.Öğe Endogenous Carboxyhemoglobin Concentrations in Predicting Prognosis of Patients with COVID-19 Pneumonia(Clin Lab Publ, 2021) Demir, Mehmet C.; Akpinar, Guleser; Sultanoglu, Hasan; Yildiz-Gulhan, Pinar; Caliskan, Emel; Guclu, Derya; Ince, NevinBackground: The coronavirus disease 2019 (COVID-19) outbreak has caused great difficulties in providing healthcare services worldwide. Accurate and useful indicators are needed for the effective use of resources. Carbon monoxide (CO) is also produced endogenously without exogenous exposure. Studies confirm that endogenous CO increases in conditions such as pneumonia, sepsis, and trauma. This study aimed to compare patients diagnosed with COVID-19 pneumonia and healthy people to reveal whether endogenous carboxyhemoglobin (COHb) levels differ. It was also to determine whether it could be a helpful indicator for the clinician in predicting disease severity in combating the COVID-19 pandemic. Methods: The study included 72 patients admitted to the hospital during the COVID-19 pandemic and diagnosed with COVID-19 pneumonia and a control group of 75 healthy people. The research data was collected retrospectively in a tertiary emergency department. The patients' demographic data, pneumonia severity index (PSI) score, CURB-65 score, 30-day mortality, hospitalization, need for mechanical ventilation (MV), and COHb levels were recorded. Results: While the COHb level was 0.9% (min-max, 0.1 - 4.0) in patients with COVID-19 pneumonia, it was 1% (min-max, 0.1 - 2.6) in the control group. No significant difference was found between the patients and the control group in terms of COHb levels (p = 0.341). Also, there was no correlation between COHb levels and PSI and CURB-65 scores. No significant difference was detected between COHb levels and patients diagnosed with COVID-19 pneumonia in terms of mortality, need for MV, or hospitalization (p > 0.05). Conclusions: We concluded that COHb levels alone could not be used to diagnose COVID-19 pneumonia or predict disease severity. Besides, in COVID-19 pneumonia, the COHb level was not a useful indicator of mortality, need for MV, or hospitalization decision. Further studies are needed to find useful indicators to assist clinicians in their decision-making process in tackling the COVID-19 pandemic.Öğe Evaluation of the Relationship Between Radial Artery Intima Media Thickness and Complications at the Intervention Site After Radial Angiography(Sage Publications Inc, 2024) Naldemir, Ibrahim Feyyaz; Karaman, Ahmet Kursat; Guclu, Derya; Ay, Esra Koc; Kayapinar, Osman; Kaya, Adnan; Sarigedik, EnesThe present study investigated the relationship between pre-procedural radial intima-media thickness (rIMT) and radial artery thrombosis (RAO) in patients undergoing angiography using a transradial approach (TRA). Patients (n = 90) who underwent cerebral or peripheral arterial angiography using TRA were included in the study. Ultrasonographic evaluation was performed before and 12 h after the procedure. Preoperative rIMT measurement was performed at the distal radial artery. Presence of radial artery occlusion was evaluated by ultrasonography after radial catheterization and revealed occlusive thrombus in the radial artery in 13 patients. rIMT was found to be statistically significantly higher in patients with thrombus (P < .05). When it was evaluated whether there was a correlation between age and rIMT, a positive significant correlation was found (P < .01). Our study suggests that increase of rIMT may be a risk factor for RAO in the intervention area. Before the procedure, ultrasound (US) assessment of the radial artery may be useful in determining the risk of occlusion. Thus, RAO-related technical risk factors (procedure time, number of punctures, sheath thickness, etc.) can be managed more carefully in patients having radial angiography.Öğe A rare cause of hearing loss: osteoma of the external auditory canal(Ma Healthcare Ltd, 2023) Guclu, Derya; Unlu, Elif N.; Ogul, Hayri[No abstract available]Öğe Shear wave elastography and T2*mapping in the detection of early-stage trochlear cartilage damage(Sage Publications Ltd, 2023) Kaplan, Meral; Guclu, Derya; Unlu, Elif Nisa; Ogul, Hayri; Onbas, OmerBackground The presence of degenerative changes in joint cartilage is one of the major features in osteoarthritis. Purpose To investigate the contribution of shear wave elastography and T2* mapping to the early diagnosis of femoral trochlear cartilage damage. Material and Methods A total of 30 individuals whose trochlear cartilage structure was evaluated as normal in conventional magnetic resonance imaging (MRI) sequences (control group) were prospectively compared with 30 patients who had early-stage cartilage damage findings on conventional MRI (study group), by performing B-mode ultrasonography, shear wave elastography, and T2* mapping. Cartilage thickness, shear wave, and T2* mapping measurements were recorded. Results After evaluating B-mode ultrasound and conventional MRI sequences, cartilage thickness was found to be significantly higher in the study group on both B-mode ultrasound and MRI. Shear wave velocity values of the study group (medial condyle [MC] 4.65 & PLUSMN; 1.11 m/sn, intercondylar [IC] 4.74 & PLUSMN; 1.20 m/sn, and lateral condyle [LC] 5.42 & PLUSMN; 1.48 m/sn) were observed to be significantly lower than the control group (MC 5.60 & PLUSMN; 0.77 m/sn, IC 5.85 & PLUSMN; 0.96 m/sn, and LC 5.63 & PLUSMN; 1.05 m/sn) (P < 0.05). T2* mapping values were significantly higher in the study group (MC 32.38 & PLUSMN; 4.04 ms, IC 35.78 & PLUSMN; 4.85 ms, and LC 34.04 & PLUSMN; 3.40 ms) than that of the control group (MC 28.07 & PLUSMN; 3.29 ms, IC 30.63 & PLUSMN; 3.45 ms, and LC 29.02 & PLUSMN; 3.24 ms). Conclusion Shear wave elastography and T2* mapping are reliable methods for evaluating early-stage trochlear cartilage damage.
