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Öğe The accuracy and validity of a weekly point-prevalence survey for evaluating the trend of hospital-acquired infections in a university hospital in Turkey(Elsevier Sci Ltd, 2011) Üstün, Cemal; Hoşoğlu, Salih; Geyik, Mehmet Faruk; Parlak, Zafer; Ayaz, CelalObjective: To evaluate the validity of a weekly point-prevalence survey (WPS) by comparing it with a prospective-active incidence survey (PIS). Methods: WPS and PIS were conducted at a tertiary referral hospital between January and December 2006. Each Wednesday, an infection control team reviewed all clinical records of patients with hospital-acquired infections (HAIs) by WPS. Routine PIS was conducted with daily visits by the same team. The Rhame and Sudderth formula was used for converting the data between WPS and PIS. Results: During the study period, 1287 HAIs were detected in 37 466 patients by WPS. The mean observed prevalence and calculated prevalence were 5.42% and 5.45%, respectively. The reanimation intensive care unit (ICU) (49.4%) and burns unit (27.6%) had the highest prevalence rates. Pneumonia (0.94%) and urinary tract infections (0.37%) were the most frequent infections. Overall 602 HAIs were detected in 545 patients by PIS. The mean observed incidence and calculated incidence were 2.42/1000-admissions and 2.41/1000-admissions, respectively. The Critical care ICU (37.0/1000-admissions) and burns unit (24.8/1000-admissions) had the highest incidences of HAI. Pneumonia (0.64/1000-admissions) and urinary tract infections (0.37/1000-admissions) were the most frequent infections. Conclusions: This study confirms a close relationship between prevalence and incidence data. WPS may be a useful method for following HAIs when PIS cannot be performed. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.Öğe Acute hepatitis: a rare complication of Epstein-Barr virus (EBV) infection(J Infection Developing Countries, 2010) Uluğ, Mehmet; Çelen, Mustafa Kemal; Ayaz, Celal; Geyik, Mehmet Faruk; Hoşoğlu, SalihInfectious Mononucleosis (IM), a benign lymphoproliferative disease, is the best known clinical syndrome caused by Epstein-Barr Virus (EBV). It usually resolves over a period of weeks or months without sequelae but may occasionally be complicated by a wide variety of neurologic, hematologic, hepatic, respiratory, and psychological complications. In this report we describe a patient with acute hepatitis following EBV-IM in a previously healthy woman. A 26-year-old woman who presented with fever, generalized weakness, nausea, sore throat, yellowing of skin, and a generalized skin rash was admitted to our clinic. Tonsillar enlargement, pharyngeal erythema, palatal petechiae, lymphadenopathy, and jaundice were noted. Significant atypical lymphocytes (> 10%) were seen on the peripheral blood smear. Liver function tests such as ALT: 303 U/L, AST: 172 U/L, ALP: 193 U/L and total bilirubin: 7.3 mg/dl were elevated. Serological tests for EBV infection were consistent with acute infection (EBV virus capsid antigen was reactive with IgM and IgG antibodies). The Monospot test was also positive. On the seventh day, liver function tests and bilirubin had risen to peak level and platelets were decreased. The patient was managed supportively and her critical condition improved and was finally stabilized. Although the prognosis for IM is very favorable, a variety of acute complications may occur.Öğe Alterations of Serum Copper and Zinc Levels, and Copper/Zinc Ratios Among Patients with Brucellosis(Ortadogu Ad Pres & Publ Co, 2012) Üstün, Cemal; Teğin, İbrahim; Geyik, Mehmet FarukObjective: To determine the alterations of serum copper (Cu) and zinc (Zn) levels and Cu/Zn ratio in patients with brucellosis. Material and Methods: A total of 170 individuals were included in the study. Of these, 45 (26.5%) currently had acute or sub-acute brucellosis, 35 (20.6%) were previously diagnosed with acute or sub-acute brucellosis and successfully treated, and 90 (52.9%) were healthy volunteers. After fasting overnight for 10 hours, 5 ml of venous blood was taken from all subjects. Serum Cu and Zn levels were measured using a Unicam 929 Atomic Absorption Spectrophotometer. SPSS 16.0 was used for data analysis. Results: Mean serum Cu levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with acute or sub-acute brucellosis and 90 healthy volunteers were 88.6 +/- 26, 58.7 +/- 13 and 56.7 +/- 16 mu g/dL, respectively. Mean serum Zn levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with and treated successfully for acute or sub-acute brucellosis and 90 healthy volunteers were 38.3 +/- 12, 58.5 +/- 14, and 55.8 +/- 13 mu g/dL, respectively. Serum Cu levels (p<0.001) and Cu/Zn ratios (p<0.001) were statistically significantly higher while serum Zn levels (p<0.001) were lower in patients with acute or sub-acute brucellosis when compared to the individuals who previously diagnosed with acute or sub-acute brucellosis and the healthy volunteers. Conclusion: This study revealed significant alterations of serum Cu and Zn levels, and Cu/Zn ratios in patients with acute or sub-acute brucellosis. Serum Cu, Zn, and Cu/Zn ratios may be available biomarkers in the course of acute or sub-acute brucellosis.Öğe Are sinus-track cultures reliable for identifying the causative agent in chronic osteomyelitis?(Springer, 2009) Uluğ, Mehmet; Ayaz, Celal; Çelen, Mustafa Kemal; Geyik, Mehmet Faruk; Hoşoğlu, Salih; Necmioğlu, SerdarThe infection of bone that contains bone marrow called osteomyelitis, and is caused by different microorganisms. In this study, we aimed to determine the diagnostic value and accuracy of cultures of material from a sinus track compared with those of cultures of bone specimens that have been controversial. Prospective study was conducted at Hospital University of Dicle, a 1,090-bed university-based hospital located in DiyarbakA +/- r, Turkey. Between May 2005 and September 2006, sinus-track cultures were compared with those of bone cultures from 43 patients with chronic osteomyelitis. The patients' mean age was 30.6 +/- A 3.6 years, and 29 (67%) male and 14 (33%) female. Organisms isolated from bone cultures were Staphylococcus 69% (29/42), Escherichia coli 9.5% (4/42), Pseudomonas aeruginosa 9.5% (4/42), Proteus mirabilis 7% (3/42), respectively. Cultures of sinus track and bone specimens gave identical results in 38% of patients. The value of bone culture in the therapy of osteomyelitis must be emphasized; it is the only reliable means of determining the responsible agent, up on which the antibiotic therapy is based. The correlation between sinus track and bone cultures was 38%, i.e., failure in the treatment for 6 patients out of 10.Öğe Associated Factor For Occupational Bloodborne Exposures At A Small General Hospital(Düzce Üniversitesi, 2013) Akpınar, Mehtap; Geyik, Mehmet Faruk; Gülenç, MustafaObjective: To evaluate epidemiology of percutaneous injury or mucous exposures (PMEs) withblood or body fluids that leads serious risks for health care workers (HCWs) at a secondary carenon-teaching general hospital.Methods: An analytic, cross-sectional, hospital-wide survey study was conducted to describethe extent and associated factors of PMEs among HCWs at the hospital.Results: The total of 118 HCWs was the participants that were represented 43.7% of totalhospital workers. The participants were 66 nurses/midwives (55.9%), 12 doctors (29.0%), 22laboratory workers (9.3%), and 18 paramedics/cleaners (20.3%). The mean age of participantswas 31.8 year (SD ± 8.0 year), and mean of working time of occupation was 9.0 year (SD ± 6.6year). The study concluded that 26 of the participants (22.0%) were reported at least oneoccupational PME in the last year. The exposure rate was reported significantly higher amongthe paramedics/cleaners (8 persons, 38.9%, p=0.19) according to the others and the mean numberof exposures was 0.94/person-year. In the multivariate analysis; short time working at theoccupation was found significant factor for high occupational exposures (p=0.040).Conclusion: Beside the other well-known associated factors, short time working at theoccupation was found as predictive factor for occupational exposures among HCWs at asecondary care non-teaching general hospitalÖğe Brain abscess due to proteus mirabilis meningitis as a complication of mastoiditis: Case report(2010) Önen, Mehmet Reşit; Üstün, Cemal; Geyik, Mehmet FarukMeningitis and intracranial abscess due to Proteus mirabilis is seen especially in the neonatal period and among the patients with immune deficiency. It was learned that 35 years old male patient who applied to the emergency room with ongoing fever, nausea and vomiting for three days have had their upper left jaw tooth out 10 days ago. As clinical and laboratory to patients with acute bacterial meningitis empirical ceftriaxone 2x2 gr/day parenteral was started. The cranial MR of the patient, that has P. mirabilis producing in their blood and cerebrospinal fluid (CSF) culture, was taken at the seventh day of hospitalization as his complaints started again. In the MR, abscess was detected in the left temporal brain of the patient and a surgical treatment was applied. Complete healing was seen eight week treatment with antibiotics after surgery. During application it was though that meningitis has occurred due to the dental surgery, however after the temporal BT, mastoiditis was detected. It was thought that meningitis and brain abscess developed on the patient was caused by mastoiditis. Even with sensitive antibiotics if no recovery is observed in patients with meningitis, intracranial abscess should be considered, also it should not be forgotten that in adults and patients with no immune deficiency meningitis due to P. mirabilis may develop. © 2010 Düzce Medical Journal.Öğe Braın Abscess Due To Proteus Mirabilis Meningitis As A Complication Of Mastoiditis: Case Report(Düzce Üniversitesi, 2010) Üstün, Cemal; Geyik, Mehmet Faruk; Önen, Mehmet ReşitMeningitis and intracranial abscess due to Proteus mirabilis is seen especially in the neonatalperiod and among the patients with immune deficiency. It was learned that 35 years old malepatient who applied to the emergency room with ongoing fever, nausea and vomiting for threedays have had their upper left jaw tooth out 10 days ago. As clinical and laboratory to patientswith acute bacterial meningitis empirical ceftriaxone 2x2 gr/day parenteral was started. Thecranial MR of the patient, that has P. mirabilis producing in their blood and cerebrospinal fluid(CSF) culture, was taken at the seventh day of hospitalization as his complaints started again.In the MR, abscess was detected in the left temporal brain of the patient and a surgical treatmentwas applied. Complete healing was seen eight week treatment with antibiotics after surgery.During application it was though that meningitis has occurred due to the dental surgery, howeverafter the temporal BT, mastoiditis was detected. It was thought that meningitis and brain abscessdeveloped on the patient was caused by mastoiditis. Even with sensitive antibiotics if norecovery is observed in patients with meningitis, intracranial abscess should be considered, alsoit should not be forgotten that in adults and patients with no immune deficiency meningitis dueto P. mirabilis may developÖğe Brucellar epididymo-orchitis in southeastern part of Turkey: an 8 year experience(Elsevier Brazil, 2010) Çelen, Mustafa Kemal; Uluğ, Mehmet; Ayaz, Celal; Geyik, Mehmet Faruk; Hoşoğlu, SalihObjective: the different clinical and laboratory features and response to treatment of patients with acute brucellar epididymo-orchitis (BEO) reporting to the reference hospital in Southeastern Anatolia of Turkey. Material and methods: in this study, 27 male patients with brucellosis, who presented with epididymitis or epididymo-orchitis (EO) at the university hospital in Diyarbakir from 1998 to 2006, were included. They were compared with the other male patients. Positive blood culture or high agglutination titers of >= 1/160 and positive clinical manifestations of brucellosis were the main criteria for diagnosing brucellosis. Results: fourteen patients had unilateral EO. Leukocytosis was present in 10 patients; all of them had initial agglutination titers of >= 1/160 and 10 patients had a positive blood culture. All patients received combined therapy with streptomycin for the first 21 days (or oral rifampicin for 6-8 weeks) with doxycycline or tetracycline for 6-8 weeks. All showed improvement, fever subsided in 3-7 days, and the scrotal enlargement and tenderness regressed. Only one patient had a relapse within one year. Conclusion: in brucellosis-endemic areas, clinicians encountering EO should consider the likelihood of brucellosis. In this study, young age was the most common risk factor, and leukocytosis and high CRP level were the most common laboratory findings. Most cases were unilateral. All patients responded to medical management very well. Conservative management with combination antibiotic therapy was adequate for managing BEO. Conclusively, brucellosis must be considered as a cause of orchitis, especially in endemic regions like Turkey.Öğe A case of brucellar spondylodiscitis involving the cervical spine(Ios Press, 2009) Nas, Kemal; Bükte, Yaşar; Üstün, Cemal; Çevik, Remzi; Geyik, Mehmet Faruk; Batmaz, İbrahimWe have presented a patient of 71-year-age with brucellar spondylodiscitis, involving the cervical spine, especially the C3-C4 segment. The patient had painful percussion of the cervical spine and passive mobilization of the neck, decreased range of motion, and cervical paravertebral tenderness; but no abnormalities observed on neurological examination. Wright agglutination test for brucella was positive at 1/320. Cervical localization for brucellar spondylodiscitis is an unusual case and should be detected and treated as early as possible. In endemic regions, spinal involvement of brucellosis should be considered in cases with fever, neck and low back pain.Öğe A Case of Mortal Klatskin Tumor with Bacteriemia after ERCP(Duzce Univ, 2015) Geyik, Mehmet Faruk; Kara, İsmail Hamdi; İnce, Nevin; Akkaş, İdris; Şen, ŞeydaDue to the late onset of symptoms, Klatskin tumors or hilar cholangiocarcinoma are usually diagnosed late and long-term life expectancy is very low. In this case, an 83-year-old female patient with diagnosis of obesity and depression was admitted to Family Medicine Outpatient Clinic in Duzce University Medical Faculty because of abdominal pain and nausea ongoing for two days. In hepatobiliary ultrasound examination made in Family Medicine Clinic, gallbladder diameter was 50 mm and bile duct was seen distended to 14 mm. With these findings the patient was assessed by Infectious Diseases and Gastroenterology Clinic. She was directed outside the province for an endoscopic retrograde cholangiopancreatography (ERCP). After ERCP clinical situation is further aggravated by developed bacteremia. Due to the late onset of symptoms of the disease, as in our case, and developing bacteremic infections, the disease has resulted in a rapid mortality. In this case, it has been evaluated that table of bacteremic infection superimposed invasive medical procedures resulted to severe prognosis and increases the mortality in elderly patient with Klatskin tumor.Öğe Critical evaluation of antimicrobial use - A Turkish university hospital example(J Infection Developing Countries, 2013) Hoşoğlu, Salih; Parlak, Zafer; Geyik, Mehmet Faruk; Palancı, YılmazIntroduction: Antimicrobials are being used unnecessarily for different reasons. The aims of this study were: assessment of the quality of antimicrobial use and determination of the factors related to correct use. Method: Antimicrobial practice at Dicle University Hospital (DUH) was evaluated with a point prevalence approach. Using a standardized data collection form, the patients' data (clinic, epidemiology, laboratory and antimicrobial use) was collected. Possible influential factors on antimicrobial use were examined. Results: In the surveillance study 1,350 inpatients were evaluated; 461 (34.1%) of them were using antimicrobials for treatment and 187 (13.9%) for prophylaxis. Antimicrobial indication was found in 355 of 461 patients (77.0%), and the number of antimicrobials was 1.8 per patient in the treatment group. The most common reason for antimicrobial use was community-acquired infection (57.9%). Pneumonia (20.4%), skin and soft tissue infections (9.11%) and urinary tract infections (7.9%) were the most common infectious diseases. Positive culture results were available for 39 patients (8.5.0%) when antimicrobial treatment started. All steps of antimicrobial use were found appropriate in 243 patients (52.7%). In multivariate analyses, clinical manifestation of infection at the beginning (p<0.001), presence of leukocyte counting (p<0.001) and prescription by an infectious disease specialist were found significantly positive factors for wholly appropriate antimicrobial use. Hospitalization with a diagnosis other than infection was found a significantly negative factor for appropriate antimicrobial use (p=0.001). Conclusion: The quality of antimicrobial use could be improved with better clinical and laboratory diagnosis and consultation with infectious diseases specialistsÖğe Demographic and Epidemiologic Features of Tick Bite Cases Who Have Applied to Emergency Service in an Endemic Region(Düzce Üniversitesi, 2010) Katırcı, Yavuz; Uzun, Hakan; Güneş, Harun; Kara, İsmail Hamdi; Geyik, Mehmet Faruk; Kandiş, HayatiAim: In this study, demographic and epidemiologic features of patients seen in emergencydepartment due to tick bites that can cause Crimean-Congo Haemorrhagic Fever were discussedwith literature data.Material and Methods: Patients seen in Yozgat State Hospital Emergency Department due totick bites between 03.01.2007 and 09.31.2007 have been included. These cases have beeninvestigated according to age, gender, job, biting part of body by the tick, settlement of patientand month in which patient came to hospital, and RNA positivity in polymerase chain reaction(PCR) or IgM antibody with ELISA were investigated. Results: 641 patients who came to emergency department due to tick bite have been includedin this study. Mean age of the cases was 41.3 ±18.3. Lower extremity bites (25.3%) were themost common type when patients investigated according to site that is bitten by the tick. 44.3%of tick bite cases were young-adults and tick bites were most commonly being seen in monthsMay, June and July. 52.1% of patients were farmer. RNA positivity in PCR and IgM antibodypositivity with ELISA were 29 cases and two cases, respectively.Conclusion: Patients who come to hospital due to tick bite should be examined carefully.Patients without any symptoms should be informed about Crimean-Congo Haemorrhagic Feverand followed until the end of incubation periodÖğe The effects of snake venom on serum copper, zinc and magnesium levels in patients with snake bite(2013) Üstün, Cemal; Teğin, İbrahim; Geyik, Mehmet FarukAmaç: Yılan ısırıkları Türkiye'nin doğu ve güneydoğu bölgelerinde sık görülen önemli bir problemdir. Bu çalışmada yılan ısırığı vakalarında serum bakır (Cu), çinko (Zn) ve magnezyum (Mg) düzeylerindeki değişiklikler araştırıldı.Yöntemler: Çalışmaya 40 yılan ısırıklı hasta ile kontrol amaçlı 80 sağlıklı gönüllü alındı. Yaklaşık 10 ml venöz kan çalışmaya alınan her bir bireyden alındı. Serum eser element düzeyleri Atomik Absorbsiyon Spektormetre cihazı kullanılarak ölçüldü. Bulgular: Çalışmaya alınan 40 yılan ısırıklı hastanın yaş ortalaması 40,1 12 yıl olup, 18'i (% 45) erkek idi. Sağlıklı 80 bireyin yaş ortalaması 40,6 10 yıl olup, 36'sı (% 45) erkek idi. Yılan ısırıklı hastaların serum Cu, Zn, ve Mg düzeyleri sırasıyla 75,8 20,9; 86,9 25,2 ve 1201 562 µg/dL bulundu. Sağlıklı gönüllülerin serum Cu, Zn, and Mg düzeyleri sırasıyla 57,6 17,2; 55,8 12,4 ve 1454 278 µg/dL bulundu. İstatistiksel olarak sağlıklı gönüllüler ile karşılaştırıldığında, yılan ısırıklı hastaların serum Cu ve Zn düzeylerinde anlamlı bir artış (p 0.001) ve serum Mg düzeylerinde anlamlı bir düşüş (p0,001) saptandı.Sonuç: Yılan zehiri, yılan ısırığı olan hastaların serum Cu, Zn ve Mg düzeyleri üzerinde anlamlı değişimler oluşturmaktadır. Yılan zehrinin serum eser element düzeylerinde oluşturduğu bu değişimlerin ileri düzey çalışmalarla araştırılması yılan ısırığı olan hastaların tedavisinde yeni gelişmeler sağlayabilir.Öğe The efficacy of dexamethasone treatment in massive enteric bleeding in typhoid fever(Sage Publications Inc, 2009) Hoşoğlu, Salih; Üstün, Cemal; Geyik, Mehmet Faruk…Öğe Endemik bir bölgede kene ısırığı nedeniyle acil servise başvuran olguların demografik ve epidemiyolojik özellikleri(2010) Kandiş, Hayati; Katırcı, Yavuz; Uzun, Hakan; Güneş, Harun; Kara, İsmail Hamdi; Geyik, Mehmet FarukAmaç: Bu çalışmada Kırım-Kongo Kanamalı Ateşine (KKKA) de neden olabilen kene ısırığı sonucu, acil servise başvuran hastaların demografik ve epidemiyolojik özellikleri, kene ısırıkları ve KKKA ile ilgili bilgiler literatür eşliğinde tartışıldı. Yöntem: Yozgat Devlet Hastane’si acil servisine 01.03.2007 ile 31.09.2007 tarihleri arasında kene ısırması nedeniyle başvuran olgular alındı. Bu olgular yaş, cinsiyet, kenenin ısırdığı bölge, geldiği yer, geldiği ay, meslekleri, polimeraz zincir reaksiyonunda RNA pozitifliği veya ELISA yöntemi ile IgM araştırıldı. Bulgular: Kene ısırması şikayeti ile acil servise başvuran 641 kene ısırığı olgusu çalışmaya alındı. Yaş ortalaması 41.318.3’tü. Kene ısırıkları lokalizasyonuna göre değerlendirildiğinde alt ekstremite ısırıkları %25.3 en sık görüldü. Kene ısırması olguları değerlendirildiğinde %44.3’ünün genç-erişkin olduğu ve en sık Mayıs, Haziran, Temmuz aylarında görüldüğü tespit edildi. Olguların %52.1 mesleği tarım ve hayvancılıktı. Bu olgulardan 29’unda PCR ile RNA pozitif, ikisinde ELISA yöntemi ile IGM pozitif idi. Sonuç: Kene ısırması şikayeti ile hastanelere başvuran olgular detaylı bir şekilde muayene edilmelidir. Semptomsuz olan olgular kene ısırması sonucu gelişebilecek KKKA hakkında bilgilendirilmeli ve takipleri inkubasyon süresi boyunca yapılmalıdır.Öğe ERCP Sonrası Bakteriyemi ile Mortal Seyreden Klatskin Tümörü Olgusu(2015) Geyik, Mehmet Faruk; Kara, İsmail Hamdi; İnce, Nevin; Akkaş, İdris; Şen, ŞeydaKlatskin tümörleri yada hiler kolanjiokarsinoma erken dönemde semptom vermemesi nedeniyle geç tanı almaktadır. Uzun dönem yaşam beklentisi oldukça düşüktür. Daha önceden obesite ve depresyon tanısı olan 83 yaşındaki bayan hasta, iki gün önce başlayan karın ağrısı, bulantı, sarılık şikâyetleriyle Düzce Üniversitesi Tıp Fakültesi Aile Hekimliği polikliniğine başvurdu. Hastanın Aile Hekimliği Polikliniğinde yapılan hepatobiliyer ultrasonografi incelenmesinde safra kesesi çapı 50 mm, koledok 14 mm ile distandü görülmüştür. Hasta Klinik-laboratuvar bulgularıyla Enfeksiyon Hastalıkları ve Gastroenteroloji Polikliniklerinde değerlendirildi. Endoskopik Retrograd Kolanjiografi (ERCP) yapılması için dış merkeze yönlendirildi. ERCP sonrası klinik durumu daha da ağırlaştıran bakteriyemi gelişmiştir. Bu olguda, klatskin tümörlü yaşlı hastada invazif tıbbi girişim üzerine eklenmiş bakteriyemik enfeksiyon tablosunun prognozu kötüleştirip mortaliteyi artırdığı irdelenmiştir.Öğe The evaluation of cultures of endotracheal aspirates and isolated bacteria in the diagnosis of ventilator-associated pneumonia(Duzce University Medical School, 2011) Uluğ, Mehmet; Çelen, Mustafa Kemal; Geyik, Mehmet Faruk; Hoşoğlu, Salih; Ayaz, CelalAim: The aim of this study was to determine the ventilator-associated pneumonia (VAP) agents in isolates from endotracheal aspirate samples obtained from patients in intensive care unit (ICU) on mechanical ventilation and their susceptibility to several antibiotics. Material and Methods: Patients that received mechanical ventilation for longer than 48 hours in the ICU were diagnosed as VAP with the clinical and microbiological criteria, were enrolled in this study. Bacteria isolated from the endotracheal aspiration samples of them were identified by conventional methods and Sceptor systems, and their antibiotic susceptibilities were investigated by the National Committee for Clinical Laboratory Standards (NCCLS). Findings: A total of 72 patients were involved in this study and 84 strains were isolated. Among these patients, 12 (14.3%) had polymicrobial etiologic agent. Most commonly encountered microorganisms were Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter spp., respectively. Most of the Gram-negative bacteria were susceptible to imipenem, amikacin and ciprofloxacin. Although methicillin resistant S. aureus rate was found %100, glycopeptides resistance was not found. It was determined that 58 (92%) of the Gram-negative bacteria produced ESBL. Results: As a result, VAP is an important and frequently seen infection in ICU. High resistance rates for antibiotics suggested that the treatment of the empirical antibiotics recommended for VAP cases should be updated according to the surveillance data. © 2011 Düzce Medical Journal.Öğe Evaluation of false negativity of the Widal test among culture proven typhoid fever cases(J Infection Developing Countries, 2008) Hoşoğlu, Salih; Boşnak, Vuslat; Akalın, Şerife; Geyik, Mehmet Faruk; Ayaz, CelalBackground: The Widal test is the most common, specific and quick diagnostic method available in the world for diagnosis of typhoid fever; however, false negativity is one of the obstructive features of the test. The aim of this study was to evaluate the associated factors with Widal test negativity in an endemic area. Methods: Widal test negativity was retrospectively analyzed among culture-proven typhoid fever cases. The potential features including age, gender, previous antibiotic usage, duration of symptoms, leucopoenia, hematocrit value, and erythrocyte sedimentation rate (ESR) were evaluated for association with Widal test negativity. Results: A total of 166 culture-proven typhoid fever cases (93 or 56.0% males) were included in the study. The mean age +/- SD was 23.3 +/- 10.6 years. Mean time of interval between first symptom and test performance time was 10.6 +/- 7.8 days. The Widal test (STO and/or STH) was found positive in 75 cases (45.2%). The statistical analyses revealed that none of these variables were significant for false negativity of the Widal test. Age was found to be a possible factor for a false negative Widal test (p=0.06). Conclusion: Of existing compatible clinical findings, age should be considered in cases of Widal test negativity.Öğe THE EVALUATION OF GERIATRIC INFECTIONS DICLE EXPERIENCE(Nobel Ilac, 2010) Uluğ, Mehmet; Çelen, Mustafa Kemal; Geyik, Mehmet Faruk; Hoşoğlu, Salih; Ayaz, CelalObjective Although successes have been achieved in the treatment of the infectious diseases with antibiotics in nowadays infectious diseases are still serious problem in the elderly This study was conducted in order to determine the pattern of clinical infectious diseases in hospitalized elderly Patients C. Material and Method In this study the data of all elderly patients aged 65 and older were hospitalized to our clinic between May 2000 and May 2005 were evaluated retrospectively We reviewed 301 patients for diagnostic studies risk factors isolated microorganisms and morbidity and mortality rates Results Infections as a cause of hospitalization were identified as the following frequency sepsis (19 2%) pneumonia (17 9%) acute gastroenteritis (16 9%) acute bacterial meningitis (5 3%) and urinaty tract infection (3 6%) respectively E colt was the most isolated microorganism in these patients Hypertension chronic obstructive pulmonary disease and diabetes were seen as risk factors in our patients Seventy three patients died during hospital stay due to their infection and chronic diseases Conclusion Under diagnosis of the elderly diseases is very common due to many factors related to elderly family members and health workers Prognosis is rather worse especially in sepsis due to pneumonia and urinary tract infectionsÖğe The evaluation of geriatric infections: Dicle experience [Geri?atri?k i?nfeksi?yonlarin de?erlendi?ri? lmesi?: Di?cle deneyi?mi?](2010) Uluğ, Mehmet; Çelen, Mustafa Kemal; Geyik, Mehmet Faruk; Hoşoğlu, Salih; Ayaz, Celal• Objective: Although successes have been achieved in the treatment of the infectious diseases with antibiotics in nowadays, infectious diseases are still serious problem in the elderly. This study was conducted in order to determine the pattern of clinical infectious diseases in hospitalized elderly patients. • Material and Method: In this study, the data of all elderly patients aged 65 and older, were hospitalized to our clinic between May 2000 and May 2005 were evaluated retrospectively. We reviewed 301 patients for diagnostic studies, risk factors, isolated microorganisms and morbidity and mortality rates. • Results: Infections as a cause of hospitalization were identified as the following frequency; sepsis (19.2%), pneumonia (17.9%), acute gastroenteritis (16.9%), acute bacterial meningitis (5.3%) and urinary tract infection (3.6%), respectively. E. coli was the most isolated microorganism in these patients. Hypertension, chronic obstructive pulmonary disease and diabetes were seen as risk factors in our patients. Seventy-three patients died during hospital stay due to their infection and chronic diseases. • Conclusion: Under diagnosis of the elderly diseases is very common due to many factors related to elderly, family members and health workers. Prognosis is rather worse especially in sepsis due to pneumonia and urinary tract infections.
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