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    Effectiveness of autologous blood injection in the treatment of lateral epicondylitis: randomized clinical study
    (Düzce Üniversitesi, 2016) Gedik, Dilay Eken; Sürücü, Gülseren Dost; Karabiber, Mehmet; Yıldırım, Adem
    Objective: The aim of this study was to investigate the short and long-term effectiveness ofautologous blood injection in the treatment of lateral epicondylitis (LE).Materials-Methods: Seventy patients diagnosed as LE were randomized as control (Group 1,n=35) and injection (Group 2, n=35) groups. In control group, epicondyle bandage and homeexercise program was applied for 4 weeks. In injection group, autologous blood was injectedinto the most tender spot around the lateral epicondyle in addition to bandage and home exerciseprogram. All patients were evaluated by a blinded investigator at baseline, 4 weeks (primaryendpoint), 3 and 6 months. The outcome measurements were algometric sensitivity, pain-freegrip strength, Patient-rated Tennis Elbow Evaluation Questionnaire, and response to treatmentscore. At the end of 4 weeks (primary endpoint), we also applied autologous blood injection topatients who had "moderate" or "poor" response to treatment in Group 1 (21/34 patients, definedas Group 3).Results: At primary endpoint, all above-mentioned parameters improved significantly in Group1 and Group 2. Improvements in Group 2 were more significant when percentage rate of changeswere compared between groups. Moreover, significant improvements continued at 3 and 6months in all groups (13 patients who remained in Group 1 after the primary endpoint; 32patients in Group 2 and 21 patients in Group 3). Conclusion: This study showed that, autologous blood injection is effective in patients with LEand this effectiveness has continued at 6 months. Therefore, autologous blood injection, whichhas relatively less side effects, might be included among long-term treatment options for LE