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Öğe Evaluation of Bone Mineral Density in Prepubertal Children with Familial Mediterranean Fever(2021) Atağ, Emine; Öcal, Sevliya; Ergüven, MüferretObjective: Familial Mediterranean Fever (FMF) is a hereditary autosomal recessive chronic periodic inflammatory disease, characterized by recurrent fever polyserositis and skin manifestations. The aim of this study was to investigate the bone mineral density (BMD) in prepubertal children with FMF and to determine the relationship between bone density and demographic, laboratory characteristics of the disease. Material and Method: Thirty two previously diagnosed, attack-free, prepubertal FMF patients who were receiving regular colchicine treatment were included in the study. Demographic and clinical data of patients, acute phase reactants, biochemical parameters of bone turnover, bone age, and L1-L4 vertebral mineral density were evaluated. The results of the patients were compared with values determined for healthy Turkish children. Results: All of the patients had z-scores which were greater than -2. Acute phase values and bone metabolism markers were within normal limits. No correlation was found between the aBMD Z-score and demographic data, acute phase reactants and bone metabolism markers. There was a negative correlation between delay in diagnosis and aBMD Z- score. Conclusion: Although aBMD Z-scores were normal in children with FMF the aBMD Z score was found to be lower in children who had had a delay in treatment. Early initiated colchicine therapy is important for optimal bone health in these patients.Öğe Hepatit B Yüzey Antijeni Pozitif Annelerin Bebeklerinde Bağışıklama Sonrası Hepatit B Serolojisinin Değerlendirilmesi(2021) Tekin, Emine; Ergüven, Müferret; Gondal, Öznur YılmazAmaç: Hepatit B yüzey antijeni (HBsAg) pozitif annelerden doğan bebeklerin bağışıklama sonrası hepatit B serolojilerini değerlendirmek, antiHBs titresinin anne yaşı, doğum şekli, bebeğin kilosu, gestasyon haftası, anne sütü alımı ve sigara maruziyeti ile ilişkisini araştırmaktır. Gereç ve Yöntem: Sağlık Bakanlığı Göztepe Eğitim Araştırma Hastanesi Kadın Doğum Kliniği’ne başvuran HBsAg antijeni pozitif olan annelerden doğan bebekler çalışmaya kabul edildi. Tüm bebeklere ilk 24 saat içinde, rekombinan hepatit B İmmünoglobulin (HBIG) ve rekombinan hepatit B aşısı kas içi yapıldı. Bebekler 0, 1, 6 ay şemasına göre aşılandı, 9-12 aylık olduklarında serum HBsAg ve anti-HBs düzeylerine bakıldı. Anne yaşı, doğum şekli ve kilosu, gestasyon haftası, anne sütü alımı ve sigara maruziyeti sorgulanarak hazırlanmış forma kaydedildi. Bulgular: Çalışmaya 50 bebek alındı. Olguların 26’sı (%52) kız, 24’ü (%48) erkek idi. Üç doz aşılamadan sonra bir bebekte HBsAg pozitif bulundu. Bu bebeğin annesinin Hepatit B e antijeni (HBeAg) de pozitifti. Altı bebek haricinde koruyucu düzeyde anti-HBs pozitifliği (%88) saptandı. Gestasyon yaşı <37 hafta olan (preterm) bebeklerde anti-HBs titresi anlamlı olarak düşük bulundu. (p=0,014) .Erkek bebeklerde, normal vajinal yolla doğanlarda, doğum kilosu >2500 gram olanlarda, 6 aydan az anne sütü alanlarda, sigara maruziyeti olmayanlarda anti-HBs düzeyleri ortalamaları daha yüksekti, ancak bu fark istatistiksel olarak anlamlı değildi. Anne yaşı ile ilişki saptanamadı. Sonuc?: Tüm gebelerde Hepatit B serolojisi taranmalı, HBsAg pozitif olanlara gerekli danışmanlık verilmeli, bebekler etkin bir şekilde bağışıklanmalı, aşı yanıtları yetersiz olduğu için prematürelere 4 doz aşılama yapılmalı ve aşı yanıtı kontrol edilmelidir. Hepatit B’den korunmada en önemli yöntem aşılamadır.Öğe Is complementary and alternative medicine an attitude among type 1 diabetic children?(Karger, 2009) Haliloğlu, Belma; Yıldız, Metin; Arslanoğlu, İlknur; İşgüven, Pınar; Ergüven, Müferret…Öğe Mothers' Knowledge Levels About Fever, Antipyretics, Febrile Illnesses, Antibiotic Use, and Febrile Convulsions(2021) Batu, Utku; Sağer, Güneş; Ergüven, MüferretIntroduction: We aimed to measure the level of knowledge about fever by reaching 300 mothers. If the level of information is found to be inadequate in accordance with the results, by alerting the authorities about the results and ensuring that they reach the public; We thought that it might be useful for many applications to hospitals, unnecessary antibiotic use, antibiotic resistance, reducing the panic level of families and relieving the state budget. As a matter of fact, we thought that the Ministry of Health is a valuable study to help the studies to be done today in order to shed light on how effective these advertisements are due to the fact that they were made before the public awareness activities and we published the information obtained today. Methods: Study was conducted with 300 mothers who applied to Pediatric Clinics between 2009-2010 under the permission of the ethics committee. Aim of correcting existing mistakes and statisticing the information we should provide to mothers. Results: 82% of the mothers who participated in our study had low socioeconomic level. Fever consciousness was low in 57% of our mothers. The rate of antibiotic use was 53%. According to the data of our study, 58% of mothers do not measure fever correctly. There is no fever measuring device in 45%. Discussion and Conclusion: We found that mothers' awareness of fever, their behaviors about febrile convulsions, and their awareness of antibiotic use were insufficient. We determined that the mother being a housewife, the mother's education level being low, socioeconomic level score was low, her husband's occupation, her husband's education was low, and fever awareness and antibiotic use were negatively affected. When we consider the results, we anticipate that mothers should be informed about fever, that they will make unnecessary applications to the child and that they will prevent delayed and inadequate intervention.
