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    A Post-Treatment Evaluation of Total IgE, CRP and Blood Count Parameters of Children With Asthma
    (Düzce Üniversitesi, 2013) Gürel, Ahmet; Donma, Mustafa Metin; Nalbantoğlu, Burçin; Topçu, Birol; Yıldız, Zeynep Deniz; Tülübaş, Feti
    Objective: We aimed to study if inhaled corticosteroid and inhaled beta 2 agonist treatment to2-18 years old children with asthma resulted in recovery in serum total IgE, CRP, and wholeblood count levels and/or to evaluate the effect of treatment in comparison to healthy children.Methods: Data regarding pre and post treatment serum total IgE, CRP, and hemogram levelsof 2-18 years old, 99 children with asthma, who received inhaled corticosteroid and inhaledbeta 2 agonist treatment and who applied to Namık Kemal University Research and PracticeHospital Pediatrics Clinic, were obtained through file scanning. Data regarding demographicsand serum total IgE, CRP and hemogram levels of 99 healthy children in control group werealso obtained through file scanning.Results: In children with asthma, levels of serum total IgE, lymphocyte, eosinophil and basophilcounts and percentages were significantly increased compared to healthy controls, and theywere significantly decreased after treatment to the levels of healthy controls. Serum CRP levels,neutrophil counts and percentages were significantly decreased compared to healthy controls,and they were significantly increased after treatment.Conclusions: Inhaled steroid and beta 2 antagonist treatment to children with asthma resultedin recovery in levels of IgE, CRP, and some whole blood count parameters through decreasinginflammation with its anti-inflammatory effect