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    Assessment of the Patients with Migraine Related Vertigo that Admitted to the Emergency Department
    (Düzce Üniversitesi, 2015) Delice, Orhan; Ceylan, Mustafa
    Objective: We aimed to provide additional information in order to prevent the misdiagnosisand malpractice in the emergency department by examining the detailed characteristics ofmigraines associated with dizziness.Material and Methods: This is a prospective and cross-sectional study. A hundred consecutivepatients applied with the complaints of both headache and dizziness to emergency departmentwithin 6 months were examined. The patients were referred to neurology polyclinic after thetreatment in emergency department. For each patient, a form containing questions about thespecific symptom, the history and the clinic characteristics was full-filled. The patients weredivided into two groups according to whether there is aura or not, and migraine in the family ornot; than the differences were examined.Results: Eighty-seven of our patients (87%) were female. Forty-one patients (41%) describedaura. Of headache,66% were unilateral and 32% were bilateral. Of the patients,83% experiencednausea, 48% experienced vomiting and 92% described photophobia and phonophobia. Theduration of headache of the migraine patients having a family history of migraine wassignificantly shorter than others. The monthly migraine frequency was significantly higher inpatients having a family history of migraine than the others.Conclusion: Among the patients having a headache and vertigo who applied to emergencydepartment, migraine associated with vertigo should be considered in the young ladies whoseheadache is unilateral and who describes photophobia and phonophobia
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    The Diagnostic Value of Soluble Urokinase Plasminogen Activator Receptor in Crimean-Congo Hemorrhagic Fever Disease in the Emergency Department
    (2021) Küçükceran, Kadir; Yılmaz, Sibel İba; Karaşahin, Ömer; Batur, Ali; Delice, Orhan; Şebin, Engin; Şenyurt, Mahmut
    Aim: The urokinase-type plasminogen activator (uPA) system consists of a protease, a receptor(urokinase-type plasminogen activator receptor, uPAR), and inhibitors that can be expressed onvarious cell types. Previous literature shows that the amount of soluble urokinase-typeplasminogen activator receptor (suPAR) secreted from affected cells is higher in Crimean-Congohemorrhagic fever (CCHF) patients than in healthy controls. Thus, we aimed to investigate thediagnostic value of suPAR in the differential diagnosis of CCHF in emergency services.Material and Methods: Individuals over 16 years old with a preliminary diagnosis of CCHFdisease were divided into two groups as real time-polymerase chain reaction (RT-PCR) and/orIgM positive (CCHF group) and RT-PCR and/or IgM negative (control group).Results: Eighty patients were included in this study. Forty patients with CCHF virus PCRand/or CCHF virus IgM were identified as CCHF group and 40 patients included as negativecontrol group. The median age of the patients was 45 (range, 16-91) years, and 49 patients(61.3%) were male. Leukocyte, platelet, and fibrinogen levels were significantly lower, whilecreatinine kinase, aPTT, and D-dimer levels were significantly higher in CCHF group. Therewas no statistically significant difference between the control group and CCHF group forSuPAR (p=0.386). In addition, control group patients not diagnosed with CCHF wereexamined, brucellosis, influenza, and pneumonia were found to be the most common.Conclusion: The use of suPAR as a biomarker in the differentiation of patients with similarfindings in emergency services was investigated and found to have no diagnostic value.