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    In Vitro Antimicrobial Susceptibility Pattern Among Stenotrophomonas Maltophilia Strains Isolated From Clinical Specimens
    (Düzce Üniversitesi, 2014) Dal, Tuba; Tekin, Recep; Deveci, Özcan; Demirkaya, Safinaz; Mete, Mahmut; Dayan, Saim; Tekin, Alicem
    Aim: In this study, the determination of in vitro antimicrobial susceptibility rates amongStenotrophomonas maltophilia strains isolated from clinical specimens was aimed.Method: A total of 60 S. maltophilia strains isolated from various clinical specimens sent toDicle University Hospital clinical microbiology laboratory between January 2006 and September2011 were included retrospectively in this study. Urine samples were inoculated onto 5% sheepblood agar and Eosin-Methylene Blue (EMB) agar media, quantitatively; other clinical sampleswere inoculated, qualitatively. Identification of S. maltophilia isolates was performed byconventional methods and fully automated microbiology system. Antimicrobial susceptibilitytests were performed by Kirby-Bauer’s disk diffusion method and by broth dilution.Results: A total of 60 S. maltophilia strains isolated from clinical specimens as 24 urine, 15blood, 11 sputum, four synovial fluids, three cerebrospinal fluids, two wound swabs and onemiddle ear materials. The resistance rates against antibiotics were detected as 85% (n=51) forpiperacillin-tazobactam, 75% (n=45) for levofloxacin, 73% (n=44) for ciprofloxacin, 57%(n=34) for trimethoprim-sulfamethoxazole, 5% (n=3) for meropenem and imipenem, and 0%(n=0) for amikacin.Conclusion: In this study, it was detected that piperacillin-tazobactam can be used as analternative option other than trimethoprim-sulfamethoxazole, for the treatment of infections dueto S. maltophilia at least in our region