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    Alopecia areata in Turkey: demographic and clinical features
    (Wiley, 2008) Kavak, Ayşe; Yeşildal, Nuray; Parlak, Ali Haydar; Gökdemir, Gonca; Aydoğan, I.; Anul, H.; Baykal, Can
    Background Alopecia areata is a complex genetic disease with still many unknown aspects, and many studies have been tried to find some clues about it. Objective We aimed to investigate the demographic and clinical characteristics of alopecia areata in Turkish patients. Methods Demographic data, localization, attack number in addition to some parameters such as disease duration, severity, age of onset, family history and ophiasis pattern were evaluated in 539 alopecia areata patients. Results The male to female ratio was 1.6 : 1. Occipital and beard-moustache areas were mostly affected. Positive family history was noticed in 24.1% of the patients. The age of onset was earlier in women than in men (P = 0.04). Severe forms showed more persistent (>= 1 year) disease duration (P = 0.00). Ophiasis was more common in severe, long duration (>= 1 year) and early onset (<= 18 years) disease (P = 0.00 for all parameters). Childhood alopecia areata (<= 18 years) was also associated with long duration of the disease (P = 0.016) and positive family history (P = 0.008) when compared with adult onset (> 18 years) alopecia areata.
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    Dyskeratosis congenita associated with three malignancies
    (European Acad Dermatology & Venereology, 2003) Baykal, Can; Kavak, Ayşe; Gülcan, P.; Büyükbabani, Nesimi
    Dyskeratosis congenita is a rare inheritable disorder characterized by abnormalities of the skin, nails and oral mucosa. Aplastic anaemia resulting from bone marrow hypoplasia is a frequent cause of death. Squamous cell carcinoma developing from leukoplakia and visceral malignancies are other complications of the disease. We report here a case of dyskeratosis congenita in a man who developed three neoplasias of different systems over a period of many years. Squamous cell carcinoma and gastric adenocarcinoma manifested 17 years after the man was diagnosed with Hodgkin's disease.
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    Lipedematous scalp: A rare entity
    (Wiley, 2008) Kavak, Ayşe; Yüceer, Deniz; Yıldırım, Ümran; Baykal, Can; Sarısoy, Hasan Tahsin
    Lipedematous scalp is characterized by increased subcutaneous thickness of the scalp without any hair change. A 50-year-old female presented with thickening of the scalp without alopecia. She had no disorder other than hypertension. Monthly sonographic measurements without any treatment showed a resolution tendency in some areas and an increased thickness in others. We discuss the characteristics of this rare and possibly underestimated entity, including differential diagnoses.
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    Nevoid hyperkeratosis of the nipple and areola: A distinct entity
    (Mosby, Inc, 2002) Baykal, Can; Büyükbabani, Nesimi; Kavak, Ayşe; Alper, Murat
    Although nevoid hyperkeratosis of the nipple and areola was initially described in 1923, there are only case reports or reviews, about it; no large series have been documented to date. The clinical features of the reported cases in the literature are not uniform, and it is questioned whether nevoid hyperkeratosis of the nipple and areola is a distinct clinicopathologic entity or a clinical presentation of various dermatoses. We describe 7 cases with hyperkeratotic nevoid lesions localized on the nipple and areola with different clinical features. None of them had any other associated dermatologic or systemic disease. Histopathologic examination was performed in 6 patients. Four of them had common histopathologic features suggesting a distinct entity, namely, nevoid hyperkeratosis of the nipple and areola; 2 of them had histopathologic features consistent with seborrheic keratosis. Seborrheic keratosis presents as sharply demarcated papules or plaques, whereas nevoid hyperkeratosis of the nipple or areola presents as a plaque diffusely involving the nipple or the areola.
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    Palmoplantar keratoderma and oral leucoplakia with cutaneous horn of the lips
    (Blackwell Publishing Ltd, 2002) Baykal, Can; Savcı, N.; Kavak, Ayşe; Kurul, Semra
    The inherited palmoplantar keratodermas (PPK) may be associated with a wide variety of other ectodermal abnormalities. The coexistence of PPK and leucoplakia may indicate the increased risk of oesophageal carcinoma in adult life. Cutaneous horn may develop over benign, precancerous, as well as malignant lesions, and frequently may be associated with actinic keratoses and Bowen's disease. On the other hand, the relationship of cutaneous horn and leucoplakia has been the subject of only a single case report. We present a case of PPK and diffuse oral leucokeratosis associated with relapsing cutaneous horn of the lips.