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Öğe Evaluation of pain scores during intravitreal injection in systemic conditions and in conjunction with medications(Sage Publications Ltd, 2025) Sezer, Taha; Altikardesler, Emir; Erdogan, Kubra; Arslan, Betul; Colak, KubraBackground: Intravitreal injection (IVI) is a common practice in today's ophthalmology clinics. The pain that patients will experience after the application may be important in compliance with the treatment. Objectives: This study aimed to investigate the correlation between various clinical characteristics of patients receiving IVI and corresponding visual analogue scale (VAS) scores (0: no pain to 10: severe pain). Design: Single-centre, Prospective study. Methods: A total of 313 participants (168 females, 145 males) with a mean age of 66.91 +/- 9.67 years underwent IVI for diabetic retinopathy (DRP), retinal vein occlusion (RVO), or age-related macular degeneration (AMD). Eye examinations, including visual acuity and intraocular pressure measurements, were also conducted, and injection indications were determined based on dilated fundus examinations and spectral domain optical coherence tomography images. Following the injections, the researchers solicited VAS scores ranging from 0 to 10 (no pain to severe pain). The study explored the relationships between clinical characteristics, headache frequency, joint and muscle pain, analgesic use, surgical history, antidepressant use, vasovagal syncope, previous injections, and VAS score. Results: The mean VAS score was 4.77 +/- 2.90. While DRP and RVO had similar VAS scores (4.95 +/- 2.98 and 5.22 +/- 2.70, respectively), the AMD group had significantly lower scores (4.09 +/- 2.64). Compared with nonusers, antidepressant users had significantly greater VAS scores (5.79 +/- 3.43) (4.52 +/- 2.70) (p < 0.05). Patients with a history of syncope had significantly greater VAS scores (p < 0.05). In patients reporting monthly headaches, a positive correlation was found between headache frequency and VAS score (r = 0.23, p < 0.01). Conclusion: For individuals experiencing daily headaches, inquiries about vasovagal syncope and antidepressant use may be beneficial, considering the potential association of these symptoms with higher VAS scores after IVIs.Öğe Evaluation of peripapillary choroidal vascularity index in young smokers(Taylor & Francis Ltd, 2023) Eski, Mehmet Tahir; Sezer, Taha; Bayraktar, Havvanur; Altikardesler, EmirPurpose: This retrospective study aimed to compare the peripapillary choroidal vascularity index (CVI) between young smokers who smoked less than 5 packs/year and non-smokers. Methods: The study included 52 smokers and 67 non-smokers, and comprehensive eye examinations were performed on all participants. Axial lengths (AL) were measured, and peripapillary enhanced depth imaging optical coherence tomography (EDI-OCT) images were obtained and evaluated using the Open Source ImageJ software. The CVI, total choroidal area ( TCA), luminal area (LA), stromal area (SA), and retinal nerve fibre layer (RNFL) quadrants were compared between the two groups. Results: The mean age of the smokers was 23.76 +/- 1.84 years, and for non-smokers, it was 23.98 +/- 2.18 years. The mean peripapillary CVI for smokers was 0.65 +/- 0.08, and for non-smokers, it was 0.67 +/- 0.03. No statistically significant difference in CVI was observed between the two groups. However, statistically significant differences were found in the temporal inferior (TI), temporal superior (TS), nasal inferior (NI), and nasal superior (NS) quadrants of the RNFL between the two groups (p < 0.05). There was no correlation between the number of packs/year and CVI values in the smoking group (r = 0.031, p = 0.826). Conclusion: The study revealed no significant difference in CVI among young smokers who smoked less than 5 packs/year compared to non-smokers. However, there was a statistically significant decrease in the TI, TS, NI, and NS quadrants of the RNFL in early-age smokers.