Yazar "Aliyev, Anar" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • Küçük Resim Yok
    Öğe
    Correlation between 18F FDG Uptake with Pathological Prognostic Factors in Breast Carcinoma
    (Springer, 2012) Ekmekçioğlu, Özgül; Aliyev, Anar; Erkan, Melih Engin; Döner, Zübeyde Rana Kaya; Çalışkan, Fatma; Başkır, B.; Sönmezoğlu, Kerim
    …
  • Küçük Resim
    Öğe
    Correlation of F-18-fluorodeoxyglucose uptake with histopathological prognostic factors in breast carcinoma
    (Lippincott Williams & Wilkins, 2013) Ekmekçioğlu, Özgül; Aliyev, Anar; Aksoy, Sabire Yılmaz; Arslan, Esra; Döner, Zübeyde Rana Kaya; Kocael, Pınar; Sönmezoğlu, Kerim
    ObjectiveThis study investigated the prognostic value of [F-18]-fluorodeoxyglucose (F-18-FDG) uptake in breast carcinomas by comparing F-18-FDG PET/computed tomography (CT) images with histopathological and immunohistochemical prognostic factors.MethodsThis study included 136 women and four men with positive biopsy breast carcinomas who underwent F-18-FDG PET/CT imaging for initial staging. Maximum standardized uptake values (SUVmax) and tumour-to-background SUVmax ratios were calculated and compared with histopathological and immunohistochemical tumour characteristics, patient properties and axillary lymph node involvement. Calculations of SUVmax for men were performed separately.ResultsFor the tumours in women, the mean SUVmax was 10.066.91 and the median SUVmax was 9.05 (0.7-35.0). Primary tumour F-18-FDG uptake and tumour-to-background SUVmax ratios were correlated with tumour size (P<0.001), histological type (P<0.001), histological grade (P=0.004), pleomorphism (P=0.010), mitosis count (P<0.001), lymphatic invasion (P=0.009), necrosis (P=0.005), oestrogen negativity (P=0.004), high Ki-67 level (P<0.001), axillary lymph node involvement (P<0.001) and triple negativity (P=0.002). High Ki-67 level (odds ratio=16; 95% confidence interval=1.6-160; P=0.016) and tumour size (odds ratio=4; 95% confidence interval=1.5-11; P=0.007) were determining factors for high F-18-FDG uptake values. Other clinicopathological and immunohistopathological parameters including progesterone receptor (P=0.211), CerbB2 overexpression (P=0.170), perineural invasion (P=0.053), intratumoural calcification (P=0.438), desmoplasia (P=0.112), tubular formation (P=0.768) and age (P=0.675) were not significantly correlated with F-18-FDG uptake. No significant relationship was observed between the tumour/contralateral breast SUVmax ratio and mitotic count, oestrogen receptor status or triple negativity.Conclusion(18)F-FDG uptake may serve as a prognostic indicator for biological behaviour in breast tumours. (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
  • Küçük Resim
    Öğe
    Pretherapy and posttherapy F-18-FDG PET/CT in isolated nasoseptal diffuse large B-cell lymphoma
    (Elsevier Doyma Sl, 2013) Asa, Sertaç; Aliyev, Anar; Aksoy, Sabire Yılmaz; Erkan, Melih Engin; Sağer, Sait; Halaç, Metin
    …
  • Küçük Resim
    Öğe
    The role of FDG PET/CT in detection of distant metastasis in the initial staging of breast cancer
    (Tubitak Scientific & Technical Research Council Turkey, 2016) Aliyev, Anar; Aksoy, Sabire Yılmaz; Özhan, Meftune; Ekmekçioğlu, Özgül; Vatankulu, Betül; Kocael, Pınar Çiğdem; Halaç, Metin
    Background/aim: We aimed to evaluate the role of FDG PET/CT in the detection of extraaxillary regional nodal/distant metastasis in breast cancer patients and to assess the value of FDG PET/CT for detecting distant metastases in patient subgroups. Materials and methods: A total of 254 patients with breast cancer (248 female, 6 male) who underwent PET/CT for initial staging were enrolled. Patients were divided into four groups: Group 1 consisted of 154 patients diagnosed by tru-cut/core/FNAB, Group 2 comprised 32 patients diagnosed by excisional biopsy, Group 3 included 62 patients who had mastectomy-axillary lymph node dissection, and Group 4 consisted of 6 patients who had axillary lymph node metastasis diagnosed by excisional biopsy. Results: PET/CT detected distant metastasis in 76 of the 254 patients. Of these patients, 21.7% had bone/bone marrow metastasis, 7.1% had lung metastasis, 13% had mediastinal lymph node metastasis, 4.8% had liver metastasis, 9.8% had other organ/system metastasis, and 6% had other lymphadenopathies. According to T staging, the percentages of distant metastasis were as follows: 13.6% of the 66 T1 stage patients, 35.7% of the 129 T2 stage patients, 40% of the 20 T3 stage patients, and 33.3% of the 39 T4 stage patients. Conclusion: FDG-PET/CT led to a change in the stage of disease and the treatment approach in newly diagnosed breast cancer patients due to its superiority in detecting extraaxillary regional lymph node metastases and distant metastases.
  • Küçük Resim
    Öğe
    The role of FDG PET/CT in detection of distant metastasis in theinitial staging of breast cancer
    (2016) Aliyev, Anar; Aksoy, Sabire Yılmaz; Özhan, Meftune; Ekmekçioğlu, Özgül; Vatankulu, Betül; Kocael, Pınar Çiğdem; Halaç, Metin
    Background/aim: We aimed to evaluate the role of FDG PET/CT in the detection of extraaxillary regional nodal/distant metastasis in breast cancer patients and to assess the value of FDG PET/CT for detecting distant metastases in patient subgroups. Materials and methods: A total of 254 patients with breast cancer (248 female, 6 male) who underwent PET/CT for initial staging were enrolled. Patients were divided into four groups: Group 1 consisted of 154 patients diagnosed by tru-cut/core/FNAB, Group 2 comprised 32 patients diagnosed by excisional biopsy, Group 3 included 62 patients who had mastectomy-axillary lymph node dissection, and Group 4 consisted of 6 patients who had axillary lymph node metastasis diagnosed by excisional biopsy. Results: PET/CT detected distant metastasis in 76 of the 254 patients. Of these patients, 21.7% had bone/bone marrow metastasis, 7.1% had lung metastasis, 13% had mediastinal lymph node metastasis, 4.8% had liver metastasis, 9.8% had other organ/system metastasis, and 6% had other lymphadenopathies. According to T staging, the percentages of distant metastasis were as follows: 13.6% of the 66 T1 stage patients, 35.7% of the 129 T2 stage patients, 40% of the 20 T3 stage patients, and 33.3% of the 39 T4 stage patients. Conclusion: FDG-PET/CT led to a change in the stage of disease and the treatment approach in newly diagnosed breast cancer patients due to its superiority in detecting extraaxillary regional lymph node metastases and distant metastases.
  • Küçük Resim Yok
    Öğe
    The role of FDG PET/CT in initial staging of patients with newly diagnosed breast cancer with an emphasis on distant metastasis
    (Springer, 2012) Aliyev, Anar; Halaç, Metin; Yılmaz, Sabire; Erkan, Melih Engin; Asa, S.; Özhan, Meftune; Sönmezoğlu, Kerim
    …